Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ken D. Yamaguchi"'
Autor:
Natalie Bruiners, Noton K. Dutta, Valentina Guerrini, Hugh Salamon, Ken D. Yamaguchi, Petros C. Karakousis, Maria L. Gennaro
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1617-1628 (2020)
The rise of drug-resistant tuberculosis poses a major risk to public health. Statins, which inhibit both cholesterol biosynthesis and protein prenylation branches of the mevalonate pathway, increase anti-tubercular antibiotic efficacy in animal model
Externí odkaz:
https://doaj.org/article/75876116b6df464f8fdbaf48363dccfd
Autor:
Donato Tedesco, Jianhuan Zhang, Lan Trinht, Guita Lalehzadeh, Rene Meisner, Ken D. Yamaguchi, Daniel L. Ruderman, Harald Dinter, Deborah A. Zajchowski
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 7, Pp 601-613 (2007)
We identified the ubiquitin-conjugating enzyme E2EPF mRNA as differentially expressed in breast tumors relative to normal tissues and performed studies to elucidate its putative role in cancer. We demonstrated that overexpression of E2-EPF protein co
Externí odkaz:
https://doaj.org/article/9017ae9d1c174fd5bd803faceed9eb13
Autor:
Tiffany Tran, Pedro Paz, Sharlene Velichko, Jill Cifrese, Praveen Belur, Ken D. Yamaguchi, Karin Ku, Parham Mirshahpanah, Anthony T. Reder, Ed Croze
Publikováno v:
International Journal of Cell Biology, Vol 2010 (2010)
We present evidence of a link between interferonβ-1b (IFN-β) and G-protein signaling by demonstrating that IFN-β can induce the expression of the negative regulator of G-protein signaling 1 (RGS1). RGS1 reduces G-protein activation and immune cell
Externí odkaz:
https://doaj.org/article/c334a8a87298419992e46ce8c0e9b067
Autor:
Ashutosh Lal, Christian López-Peña, Gunmeet Bali, Cassandra D Calloway, Hugh Salamon, Katie T. Carlberg, Henry A. Erlich, Shelly Shih, Ken D. Yamaguchi, Reena Das
Publikováno v:
The Journal of Applied Laboratory Medicine. 7:515-531
Background Noninvasive prenatal testing (NIPT) of chromosomal aneuploidies based on next-generation sequencing (NGS) analysis of fetal DNA in maternal plasma is well established, but testing for autosomal recessive disorders remains challenging. NGS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e549f36b7a98769a8348c9174737f88f
https://doi.org/10.1093/jalm/jfab118
https://doi.org/10.1093/jalm/jfab118
Autor:
Maria Laura Gennaro, Petros C. Karakousis, Valentina Guerrini, Hugh Salamon, Natalie Bruiners, Ken D. Yamaguchi, Noton K. Dutta
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 61, Iss 12, Pp 1617-1628 (2020)
Journal of Lipid Research, Vol 61, Iss 12, Pp 1617-1628 (2020)
The rise of drug-resistant tuberculosis poses a major risk to public health. Statins, which inhibit both cholesterol biosynthesis and protein prenylation branches of the mevalonate pathway, increase anti-tubercular antibiotic efficacy in animal model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea347c241b93f33c3bce3f2b688746f
http://europepmc.org/articles/PMC7707180
http://europepmc.org/articles/PMC7707180
Autor:
Petros C. Karakousis, Valentina Guerrini, Maria Laura Gennaro, Noton K. Dutta, Ken D. Yamaguchi, Hugh Salamon, Natalie Bruiners
Statins, which inhibit both cholesterol biosynthesis and protein prenylation branches of the mevalonate pathway, increase anti-tubercular antibiotic efficacy in animal models. We investigated the mechanism of anti-tubercular action of simvastatin in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44971232a7c3be05ed7cf9e760b85913
https://doi.org/10.1101/2020.03.04.977579
https://doi.org/10.1101/2020.03.04.977579
Autor:
Valentina Guerrini, Petros C. Karakousis, Maria Laura Gennaro, Noton K. Dutta, Ken D. Yamaguchi, Hugh Salamon, Natalie Bruiners
Publikováno v:
SSRN Electronic Journal.
Background: Statins, which inhibit both cholesterol biosynthesis and protein prenylation branches of the mevalonate pathway, increase the efficacy of anti-tubercular antibiotics in animal models. A previous report proposed that the anti-tubercular ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14c336964b432297f7fd24321c7c4f9d
https://doi.org/10.2139/ssrn.3552811
https://doi.org/10.2139/ssrn.3552811
Autor:
Ken D. Yamaguchi, Hugh Salamon, Janani Ravi, Lanbo Shi, Richard Pine, Natalie Bruiners, Karim Lakehal, Maria Laura Gennaro
Publikováno v:
The Journal of Immunology. 193:30-34
Vitamin D has long been linked to resistance to tuberculosis, an infectious respiratory disease that is increasingly hard to treat because of multidrug resistance. Previous work established that vitamin D induces macrophage antimicrobial functions ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a75006a7ee3df29a4f5286591cf1cc2d
https://doi.org/10.4049/jimmunol.1400736
https://doi.org/10.4049/jimmunol.1400736
Autor:
Alexander C. Zambon, Patrick H. Campbell, Jeffrey H. Omens, Ken D. Yamaguchi, Darlene Hunt, Karen Vranizan, Andrew D. McCulloch, Hai-Chien Kuo, Sylvia M. Evans
Publikováno v:
Experimental Physiology. 97:102-114
The Murphy Roths Large (MRL) mouse, a strain capable of regenerating right ventricular myocardium, has a high postmyocardial infarction (post-MI) survival rate compared with C57BL/6J (C57) mice. The biological processes responsible for this survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::043a402b0dd9dc7f4f6ad3e8184c7933
https://doi.org/10.1113/expphysiol.2011.060269
https://doi.org/10.1113/expphysiol.2011.060269
Autor:
Johanna Beekman, T. Charis Wagner, Hugh Salamon, Sharlene Velichko, Kemal Hamamcioglu, H. Daniel Perez, Anthony T. Reder, Ken D. Yamaguchi, Karin Ku, Ed Croze
Publikováno v:
Journal of Interferon & Cytokine Research. 28:317-331
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS). Interferon-beta (IFN-beta) therapy for MS is hypothesized to cause short-term and long-term changes in gene expression that shift the inflammation from Th1 to Th2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b3f4804017c0e8cb8602de6c8942a5
https://doi.org/10.1089/jir.2007.0131
https://doi.org/10.1089/jir.2007.0131