Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ken D. Roth"'
Autor:
Timothy P. Burkholder, Sandaruwan Geeganage, Ming-Shang Kuo, Sean Buchanan, Ken D. Roth, Maria-Carmen Fernandez, James R. Gillig, Miriam Del Prado, Shobha Bhattachar, Wenjuan Wu, Robert L. Johnson, Lisa Kays, Xueqian Gong, Bo Tan, Tao Wang, Sucai Dong, Robert Shepard, Lourdes Prieto, Yu-Hua Hui, Colin F. Green, Genshi Zhao
The concentrations of LSN3154567 in the dog plasma samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e6822518f21d94bca7c1d9980cb9dc
https://doi.org/10.1158/1535-7163.22510030.v1
https://doi.org/10.1158/1535-7163.22510030.v1
Autor:
Timothy P. Burkholder, Sandaruwan Geeganage, Ming-Shang Kuo, Sean Buchanan, Ken D. Roth, Maria-Carmen Fernandez, James R. Gillig, Miriam Del Prado, Shobha Bhattachar, Wenjuan Wu, Robert L. Johnson, Lisa Kays, Xueqian Gong, Bo Tan, Tao Wang, Sucai Dong, Robert Shepard, Lourdes Prieto, Yu-Hua Hui, Colin F. Green, Genshi Zhao
NAMPT, an enzyme essential for NAD+ biosynthesis, has been extensively studied as an anticancer target for developing potential novel therapeutics. Several NAMPT inhibitors have been discovered, some of which have been subjected to clinical investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aee608d35f9d18aa0d631046f9435f6
https://doi.org/10.1158/1535-7163.c.6539479
https://doi.org/10.1158/1535-7163.c.6539479
Autor:
Timothy P. Burkholder, Sandaruwan Geeganage, Ming-Shang Kuo, Sean Buchanan, Ken D. Roth, Maria-Carmen Fernandez, James R. Gillig, Miriam Del Prado, Shobha Bhattachar, Wenjuan Wu, Robert L. Johnson, Lisa Kays, Xueqian Gong, Bo Tan, Tao Wang, Sucai Dong, Robert Shepard, Lourdes Prieto, Yu-Hua Hui, Colin F. Green, Genshi Zhao
Table S1: anti-proliferative activity of LSN3154567 against different cancer cell lines; Table S2: effects of NAM on the anti-proliferative activity of LSN3154567
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f70612a84c12c12c5e1209c6248e3b6
https://doi.org/10.1158/1535-7163.22510024
https://doi.org/10.1158/1535-7163.22510024
Autor:
Timothy P. Burkholder, Sandaruwan Geeganage, Ming-Shang Kuo, Sean Buchanan, Ken D. Roth, Maria-Carmen Fernandez, James R. Gillig, Miriam Del Prado, Shobha Bhattachar, Wenjuan Wu, Robert L. Johnson, Lisa Kays, Xueqian Gong, Bo Tan, Tao Wang, Sucai Dong, Robert Shepard, Lourdes Prieto, Yu-Hua Hui, Colin F. Green, Genshi Zhao
Addition of NA rescued the inhibitory activity of LSN3154567.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ceca73088ab401f7f49c9843a276a7
https://doi.org/10.1158/1535-7163.22510042
https://doi.org/10.1158/1535-7163.22510042
Autor:
Timothy P. Burkholder, Sandaruwan Geeganage, Ming-Shang Kuo, Sean Buchanan, Ken D. Roth, Maria-Carmen Fernandez, James R. Gillig, Miriam Del Prado, Shobha Bhattachar, Wenjuan Wu, Robert L. Johnson, Lisa Kays, Xueqian Gong, Bo Tan, Tao Wang, Sucai Dong, Robert Shepard, Lourdes Prieto, Yu-Hua Hui, Colin F. Green, Genshi Zhao
Addition of NAM rescued the inhibitory activity of LSN3154567
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bcb7f006df51f1b22045b2d1feaf1e
https://doi.org/10.1158/1535-7163.22510036
https://doi.org/10.1158/1535-7163.22510036
Autor:
Timothy P. Burkholder, Sandaruwan Geeganage, Ming-Shang Kuo, Sean Buchanan, Ken D. Roth, Maria-Carmen Fernandez, James R. Gillig, Miriam Del Prado, Shobha Bhattachar, Wenjuan Wu, Robert L. Johnson, Lisa Kays, Xueqian Gong, Bo Tan, Tao Wang, Sucai Dong, Robert Shepard, Lourdes Prieto, Yu-Hua Hui, Colin F. Green, Genshi Zhao
Association of NAPRT1 expression level with sensitivity of cancer cells to NAMPT inhibition by LSN3154567 in the presence of NA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de57bd307d5cde24b259e24180abd7b6
https://doi.org/10.1158/1535-7163.22510027.v1
https://doi.org/10.1158/1535-7163.22510027.v1
Autor:
Burkholder Timothy P, Maria-Carmen Fernandez, Gillig James Ronald, Lourdes Prieto, Miriam del Prado, Bo Tan, Genshi Zhao, Tao Wang, Robert L. Johnson, Yu-Hua Hui, Ken D. Roth, Shobha N. Bhattachar, Sean Buchanan, Xueqian Gong, Sandaruwan Geeganage, Robert L. Shepard, Ming-Shang Kuo, Colin F. Green, Lisa Kays, Wenjuan Wu, Sucai Dong
Publikováno v:
Molecular Cancer Therapeutics. 16:2677-2688
NAMPT, an enzyme essential for NAD+ biosynthesis, has been extensively studied as an anticancer target for developing potential novel therapeutics. Several NAMPT inhibitors have been discovered, some of which have been subjected to clinical investiga