Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ken Coleman"'
Autor:
Ken Coleman
¡Vivir desmotivado en el trabajo es una realidad que toca a muchos! No todos estamos donde queremos estar, donde nos sentimos apreciados y útiles y, sobre todo, donde somos felices. Con unos cambios en el panorama mundial tan complicado tanto a niv
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:1931-1934
The novel β-lactamase inhibitor avibactam is a potent inhibitor of class A, class C, and some class D enzymes. The in vitro antibacterial activity of the ceftazidime-avibactam combination was determined for a collection of Enterobacteriaceae clinica
Publikováno v:
Health security. 14(6)
The subject of terrorism risk can be confusing for both the general public and for those responsible for protecting us from attack. Relatively minor terrorist threats are often conflated with much more serious ones, in part because it is hard to quan
Autor:
Ken Coleman
The motivating host of one of the nation's largest leadership conferences offers a collection of inspirational and applicable life lessons through conversations with various high profile people.Albert Einstein once said, “To raise new questions, ne
Autor:
Ken Coleman
Publikováno v:
Drug Discovery Today: Therapeutic Strategies. 3:183-188
The β-lactams have been a major class of antibacterial agents for the past half century, but resistance to the class is widespread. The primary resistance mechanism is a collection of enzymes known as β-lactamases that are capable of hydrolyzing th
Autor:
Ken Coleman
Publikováno v:
Drug Discovery Today: Therapeutic Strategies. 1:455-460
Gram-positive bacteria lack many of the complex permeation and export pathways found in Gram-negative bacteria, making them usually more amenable to antibacterial therapy. Yet, despite this, resistance to antibacterial agents is a widespread and grow
Autor:
Ken Coleman, Premavathy Levasseur, David M. Shlaes, Wright W. Nichols, Anne-Marie Girard, Henri Merdjan, Christine Miossec, Monica Borgonovi, George L. Drusano
Avibactam is a novel non-β-lactam β-lactamase inhibitor that is currently undergoing phase 3 clinical trials in combination with ceftazidime. Ceftazidime is hydrolyzed by a broad range of β-lactamases, but avibactam is able to inhibit the majority
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befa8fcb978238d8e54e7d3e12272d33
https://europepmc.org/articles/PMC4068505/
https://europepmc.org/articles/PMC4068505/
Autor:
David Charnuska, Ekaterina Gavrish, E. Jeffrey North, Ida Lister, Chao Chen, Kim Lewis, Michael D. LaFleur, Richard E. Lee, Binu Shrestha, Lei Yang, Bronwyn Williams, Angel Han, Ken Coleman
A high-throughput screen (HTS) was performed to identify molecules specifically active against Helicobacter pylori , the causative agent of peptic ulcer and gastric carcinoma. Currently, treatment of H. pylori infection is suboptimal, with failure ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da10a578eb4720a8ff2de3b3e0a9874f
https://europepmc.org/articles/PMC4068456/
https://europepmc.org/articles/PMC4068456/
Autor:
Ken Coleman
Talking on Air: A Broadcaster's Life in Sports highlights the 40-year career of Ken Coleman. The book details a broadcasting life seen not only from inside the booth, but also from inside the minds and throughout the experiences of many of sports'gre
Autor:
Joshua N. Adkins, Vincent M. Isabella, Kim Lewis, Laura E. Fleck, Steven N. Leonard, Richard D. Smith, Ken Coleman, Michael D. LaFleur, Brian P. Conlon, Ernesto S. Nakayasu
Publikováno v:
Nature. 503(7476)
Chronic infections are difficult to treat with antibiotics but are caused primarily by drug-sensitive pathogens. Dormant persister cells that are tolerant to killing by antibiotics are responsible for this apparent paradox. Persisters are phenotypic