Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Ken Cadwell"'
Autor:
Shushan Sargsian, Octavio Mondragón-Palomino, Alannah Lejeune, Defne Ercelen, Wen-Bing Jin, Alan Varghese, Yvonne A. L. Lim, Chun-Jun Guo, P’ng Loke, Ken Cadwell
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract Background Parasitic helminths influence the composition of the gut microbiome. However, the microbiomes of individuals living in helminth-endemic regions are understudied. The Orang Asli, an indigenous population in Malaysia with high burde
Externí odkaz:
https://doaj.org/article/acc61c8d0cf043ae85aaf58f97e2fbfd
Autor:
Ashira Lubkin, Lucie Bernard-Raichon, Ashley L. DuMont, Ana Mayela Valero Jimenez, Gregory G. Putzel, Juan Gago, Erin E. Zwack, Olufolakemi Olusanya, Kristina M. Boguslawski, Simone Dallari, Sophie Dyzenhaus, Christin Herrmann, Juliana K. Ilmain, Georgia L. Isom, Miranda Pawline, Andrew I. Perault, Sofya Perelman, William E. Sause, Ifrah Shahi, Amelia St. John, Rebecca Tierce, Xuhui Zheng, Chunyi Zhou, Maria G. Noval, Anna O'Keeffe, Magda Podkowik, Sandra Gonzales, Kenneth Inglima, Ludovic Desvignes, Sarah E. Hochman, Kenneth A. Stapleford, Lorna E. Thorpe, Alejandro Pironti, Bo Shopsin, Ken Cadwell, Meike Dittmann, Victor J. Torres
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Severe COVID-19 has been associated with coinfections with bacterial and fungal pathogens. Notably, patients with COVID-19 who develop Staphylococcus aureus bacteremia exhibit higher rates of mortality than those infected with either pathoge
Externí odkaz:
https://doaj.org/article/623845162cdd4f2baf78452f589aa583
Autor:
Simone Dallari, Vicky Martinez Pazos, Juan Munoz Eusse, Judith Wellens, Craig Thompson, Jean-Frederic Colombel, Jack Satsangi, Ken Cadwell, Serre-Yu Wong, ICARUS-IBD Working Group
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract While differential antibody responses SARS-CoV-2 in patients with inflammatory bowel disease (IBD) receiving infliximab and vedolizumab are well-characterized, the immune pathways underlying these differences remain unknown. Prior to COVID-1
Externí odkaz:
https://doaj.org/article/d097121319674b2b89b25aece89b4326
Autor:
Ghaffar Muharram, Marion Thépaut, Pierre-Emmanuel Lobert, Teddy Grandjean, Olivier Boulard, Myriam Delacre, Emmrich Wakeford, Richard Wheeler, Lionel Franz Poulin, Ivo Gomperts Boneca, Frank Lafont, Marie-Cécile Michallet, Didier Hober, Ken Cadwell, Mathias Chamaillard
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTOver 90% of epidemic non-bacterial gastroenteritis are caused by human noroviruses (NoVs), which persist in a substantial subset of people allowing their spread worldwide. This has led to a significant number of endemic cases and up to 70,000
Externí odkaz:
https://doaj.org/article/82e1ea85018e431fa5bf296b5b136da8
Autor:
Bruno A. Rodriguez-Rodriguez, Grace O. Ciabattoni, Ralf Duerr, Ana M. Valero-Jimenez, Stephen T. Yeung, Keaton M. Crosse, Austin R. Schinlever, Lucie Bernard-Raichon, Joaquin Rodriguez Galvan, Marisa E. McGrath, Sanjay Vashee, Yong Xue, Cynthia A. Loomis, Kamal M. Khanna, Ken Cadwell, Ludovic Desvignes, Matthew B. Frieman, Mila B. Ortigoza, Meike Dittmann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Small animal models have been a challenge for the study of SARS-CoV-2 transmission, with most investigators using golden hamsters or ferrets. Mice have the advantages of low cost, wide availability, less regulatory and husbandry challenges,
Externí odkaz:
https://doaj.org/article/4f82157bf5264550bc33dcd07d963594
Autor:
Amicha Robertson, Joseph Sall, Mericien Venzon, Janet J Olivas, Xuhui Zheng, Michael Cammer, Noelle Antao, Chunyi Zhou, Joseph C Devlin, Rafaela Saes Thur, Jeffrey Bethony, Peter Nejsum, Bo Shopsin, Victor J Torres, Feng-Xia Liang, Ken Cadwell
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011647 (2023)
The bacterial microbiota promotes the life cycle of the intestine-dwelling whipworm Trichuris by mediating hatching of parasite eggs ingested by the mammalian host. Despite the enormous disease burden associated with Trichuris colonization, the mecha
Externí odkaz:
https://doaj.org/article/cc392483bb274eae93333f24cf78f713
Autor:
Aarti Pant, Xiaomin Yao, Aude Lavedrine, Christophe Viret, Jacob Dockterman, Swati Chauhan, Chong-Shan Shi, Ravi Manjithaya, Ken Cadwell, Thomas A. Kufer, John H. Kehrl, Jörn Coers, L. David Sibley, Mathias Faure, Gregory A. Taylor, Santosh Chauhan
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 438-515 (2022)
Autophagy is a highly conserved process that utilizes lysosomes to selectively degrade a variety of intracellular cargo, thus providing quality control over cellular components and maintaining cellular regulatory functions. Autophagy is triggered by
Externí odkaz:
https://doaj.org/article/ededc1436aa54be2b91d4027a2d2bcfe
Autor:
Mian Zi Tee, Yi Xian Er, Alice V. Easton, Nan Jiun Yap, Ii Li Lee, Joseph Devlin, Ze Chen, Kee Seong Ng, Poorani Subramanian, Angelina Angelova, Oyebola Oyesola, Shushan Sargsian, Romano Ngui, Daniel P. Beiting, Christopher Chiong Meng Boey, Kek Heng Chua, Ken Cadwell, Yvonne Ai Lian Lim, P’ng Loke, Soo Ching Lee
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Background While microbiomes in industrialized societies are well characterized, indigenous populations with traditional lifestyles have microbiomes that are more akin to those of ancient humans. However, metagenomic data in these population
Externí odkaz:
https://doaj.org/article/689879fe71ee43f6b8a39ed95e7760c3
Autor:
Lucie Bernard-Raichon, Mericien Venzon, Jon Klein, Jordan E. Axelrad, Chenzhen Zhang, Alexis P. Sullivan, Grant A. Hussey, Arnau Casanovas-Massana, Maria G. Noval, Ana M. Valero-Jimenez, Juan Gago, Gregory Putzel, Alejandro Pironti, Evan Wilder, Yale IMPACT Research Team, Lorna E. Thorpe, Dan R. Littman, Meike Dittmann, Kenneth A. Stapleford, Bo Shopsin, Victor J. Torres, Albert I. Ko, Akiko Iwasaki, Ken Cadwell, Jonas Schluter
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here, the authors show that SARS-CoV-2 infection causes gut microbiome dysbiosis and gut epithelial cell alterations in a mouse model, and correlate dysbiosis observed in COVID-19 patients with blood stream infections, matching reads of bacterial seq
Externí odkaz:
https://doaj.org/article/1e9e329dabff4d05a3ee9e3f9ac67097
Autor:
Dessie Abera, Ayinalem Alemu, Adane Mihret, Abel Abera Negash, Woldaregay Erku Abegaz, Ken Cadwell
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293528 (2023)
BackgroundGut commensal bacteria can mediate resistance against pathogenic bacteria. However, exposure to antibiotics and hospitalization may facilitate the emergence of multidrug resistant bacteria. We aimed to conduct a systematic review and meta-a
Externí odkaz:
https://doaj.org/article/2606d89caa324ac58b6e0af0a386d478