Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Ken B, Waites"'
Autor:
Susanne Paukner, Lisa Goldberg, Elizabeth Alexander, Anita F. Das, Stefanie Heinrich, Pritty Patel, Gregory J. Moran, Christian Sandrock, Thomas M. File, Jr, Jorge E. Vidal, Ken B. Waites, Steven P. Gelone, Jennifer Schranz
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 29, Iss , Pp 434-443 (2022)
ABSTRACT: Objectives: Lefamulin, a pleuromutilin antibiotic approved for community-acquired bacterial pneumonia (CABP), was evaluated for microbiological efficacy in a prespecified pooled analysis of LEAP 1 and 2 phase 3 clinical trial data in patien
Externí odkaz:
https://doaj.org/article/b25260462ba347a2b3d84fe43c453273
Autor:
Fengyuan Huang, Li Xiao, Min Gao, Ethan J. Vallely, Kevin Dybvig, T. Prescott Atkinson, Ken B. Waites, Zechen Chong
Publikováno v:
BMC Genomics, Vol 23, Iss S4, Pp 1-12 (2022)
Abstract Background Accurate bacteria genome de novo assembly is fundamental to understand the evolution and pathogenesis of new bacteria species. The advent and popularity of Third-Generation Sequencing (TGS) enables assembly of bacteria genomes at
Externí odkaz:
https://doaj.org/article/42b6f007995d46e68c29221e654e966f
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Here, we performed in vitro susceptibility testing on 10 Mycoplasma genitalium isolates against omadacycline, minocycline, tetracycline, doxycycline, moxifloxacin, levofloxacin, and azithromycin. Omadacycline was the most potent agent, with
Externí odkaz:
https://doaj.org/article/ddd02f2fadf747c5b02750ca9c7c4141
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Mycoplasma salivarium, an oral commensal organism, can cause severe invasive infections in immunocompromised individuals. Currently there is no treatment guidance for such infections. We performed antimicrobial susceptibility tests on 39 commensal an
Externí odkaz:
https://doaj.org/article/cf7ca7ba98c544d18b7b6c57f6356711
Autor:
Susanne Paukner, David Mariano, Anita F. Das, Gregory J. Moran, Christian Sandrock, Ken B. Waites, Thomas M. File
Publikováno v:
Antibiotics, Vol 10, Iss 12, p 1489 (2021)
Lefamulin was the first systemic pleuromutilin antibiotic approved for intravenous and oral use in adults with community-acquired bacterial pneumonia based on two phase 3 trials (Lefamulin Evaluation Against Pneumonia [LEAP]-1 and LEAP-2). This poole
Externí odkaz:
https://doaj.org/article/76c7e81345964cbda5fd2343e3fce190
Autor:
Steven P Gelone, Susanne Paukner, Christian Sandrock, Jennifer Schranz, Anita Das, Thomas M. File, Lisa Goldberg, Ken B. Waites, Jorge E. Vidal, Stefanie Heinrich, Elizabeth Alexander, Gregory J. Moran, Pritty Patel
Publikováno v:
Journal of Global Antimicrobial Resistance. 29:434-443
Background : Lefamulin, a pleuromutilin antibiotic approved for community-acquired bacterial pneumonia (CABP), was evaluated for microbiological efficacy in a prespecified pooled analysis of LEAP 1 and 2 phase 3 clinical trial data in patients with C
Autor:
Ken B. Waites, Donna M. Crabb, Amy E. Ratliff, William M. Geisler, T. Prescott Atkinson, Li Xiao
Publikováno v:
J Clin Microbiol
Mycoplasma genitalium is an important sexually transmitted pathogen affecting both men and women. Its extremely slow growth in vitro and very demanding culture requirements necessitate the use of molecular-based diagnostic tests for its detection in
Autor:
Patrick C Tam, Barbara D Alexander, Mark J Lee, Rochelle G Hardie, John M Reynolds, John C Haney, Ken B Waites, Arthur W Baker
Publikováno v:
Open Forum Infectious Diseases. 9
Background Mollicutes, such as Mycoplasma hominis and Ureaplasma spp, are fastidious bacteria that can cause invasive donor-derived infections in lung transplant recipients. Best practices for donor screening and recipient surveillance for Mollicute
Autor:
T Prescott Atkinson, Robert M Centor, Li Xiao, Fuchenchu Wang, Xiangqin Cui, William Van Der Pol, Casey D Morrow, Amy E Ratliff, Donna M Crabb, Arthur H Totten, Carlos A Estrada, Michael B Faircloth, Ken B Waites
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0189423 (2018)
Fusobacterium necrophorum (Fn), a gram-negative anaerobe, is increasingly implicated as an etiologic agent in older adolescents and young adults with sore throat. Inadequately treated Fn pharyngitis may result in suppurative complications such as per
Externí odkaz:
https://doaj.org/article/9fb171f15f454b6cbc10c0a14654e16b
Autor:
Trudy H. Grossman, Corey Fyfe, William O’Brien, Meredith Hackel, Mary Beth Minyard, Ken B. Waites, Jacques Dubois, Timothy M. Murphy, Andrew M. Slee, William J. Weiss, Joyce A. Sutcliffe
Publikováno v:
mSphere, Vol 2, Iss 1 (2017)
ABSTRACT TP-271 is a novel, fully synthetic fluorocycline antibiotic in clinical development for the treatment of respiratory infections caused by susceptible and multidrug-resistant pathogens. TP-271 was active in MIC assays against key community re
Externí odkaz:
https://doaj.org/article/fc839a5a5190439892aac4f57b1d746e