Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ken André Olaussen"'
Autor:
Damien Vasseur, Ludovic Bigot, Kristi Beshiri, Juan Flórez-Arango, Francesco Facchinetti, Antoine Hollebecque, Lambros Tselikas, Mihaela Aldea, Felix Blanc-Durand, Anas Gazzah, David Planchard, Ludovic Lacroix, Noémie Pata-Merci, Catline Nobre, Alice Da Silva, Claudio Nicotra, Maud Ngo-Camus, Floriane Braye, Sergey I. Nikolaev, Stefan Michiels, Gérôme Jules-Clement, Ken André Olaussen, Fabrice André, Jean-Yves Scoazec, Fabrice Barlesi, Santiago Ponce, Jean-Charles Soria, Benjamin Besse, Yohann Loriot, Luc Friboulet
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Understanding the resistance mechanisms of tumor is crucial for advancing cancer therapies. The prospective MATCH-R trial (NCT02517892), led by Gustave Roussy, aimed to characterize resistance mechanisms to cancer treatments throu
Externí odkaz:
https://doaj.org/article/e6a5668f34d34175ab097af1e5bb22e4
Autor:
Lorenzo Galluzzi, Ilio Vitale, Laura Senovilla, Ken André Olaussen, Guillaume Pinna, Tobias Eisenberg, Aïcha Goubar, Isabelle Martins, Judith Michels, Gueorgui Kratassiouk, Didac Carmona-Gutierrez, Marie Scoazec, Erika Vacchelli, Frederic Schlemmer, Oliver Kepp, Shensi Shen, Maximilien Tailler, Mireia Niso-Santano, Eugenia Morselli, Alfredo Criollo, Sandy Adjemian, Mohamed Jemaà, Kariman Chaba, Claire Pailleret, Mickaël Michaud, Federico Pietrocola, Nicolas Tajeddine, Thibault de La Motte Rouge, Natalia Araujo, Nadya Morozova, Thomas Robert, Hugues Ripoche, Frederic Commo, Benjamin Besse, Pierre Validire, Pierre Fouret, Angélique Robin, Nicolas Dorvault, Philippe Girard, Sébastien Gouy, Patricia Pautier, Nora Jägemann, Ann-Christin Nickel, Sabrina Marsili, Caroline Paccard, Nicolas Servant, Philippe Hupé, Carmen Behrens, Parviz Behnam-Motlagh, Kimitoshi Kohno, Isabelle Cremer, Diane Damotte, Marco Alifano, Øivind Midttun, Per Magne Ueland, Vladimir Lazar, Philippe Dessen, Hans Zischka, Etienne Chatelut, Maria Castedo, Frank Madeo, Emmanuel Barillot, Juergen Thomale, Ignacio Ivan Wistuba, Catherine Sautès-Fridman, Laurence Zitvogel, Jean-Charles Soria, Annick Harel-Bellan, Guido Kroemer
Publikováno v:
Cell Reports, Vol 2, Iss 2, Pp 257-269 (2012)
Patients with non-small cell lung cancer (NSCLC) are routinely treated with cytotoxic agents such as cisplatin. Through a genome-wide siRNA-based screen, we identified vitamin B6 metabolism as a central regulator of cisplatin responses in vitro and i
Externí odkaz:
https://doaj.org/article/c962346fede94134a0ec7d5f7e6f4ffd
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
PDF file - 81K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35eea7db712006912b959d23558ba756
https://doi.org/10.1158/1078-0432.22442309.v1
https://doi.org/10.1158/1078-0432.22442309.v1
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
XLS file - 15K, Mutations details
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16f7263fade1df2723063489e4d4c73
https://doi.org/10.1158/1078-0432.22442303
https://doi.org/10.1158/1078-0432.22442303
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
PDF file - 171K, Frequencies of gain, or loss, according to ERCC1-IHC status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdb66dd10fdbfa4b2b139ff1ebdcfb8
https://doi.org/10.1158/1078-0432.22442312.v1
https://doi.org/10.1158/1078-0432.22442312.v1
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
XLS file - 14K, List of Top 29 miRNA differentially expressed between the two groups ERCC1 positive / negative used for patients hierarchical clustering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d817e17f708fbba3777e72a3b7db8d3
https://doi.org/10.1158/1078-0432.22442306.v1
https://doi.org/10.1158/1078-0432.22442306.v1
Data from Molecular Characteristics of ERCC1-Negative versus ERCC1-Positive Tumors in Resected NSCLC
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
Purpose: Excision repair cross-complementation group 1 (ERCC1) is a protein involved in repair of DNA platinum adducts and stalled DNA replication forks. We and others have previously shown the influence of ERCC1 expression upon survival rates and be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200a3a66bcaaa0c46e55c241e42f6c42
https://doi.org/10.1158/1078-0432.c.6519074
https://doi.org/10.1158/1078-0432.c.6519074
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
XLS file - 30K, List of 149 significantly differential genes between the two groups ERCC1 positive / negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a36f8ab4c95fc3fe5e31f7116b5b2b5
https://doi.org/10.1158/1078-0432.22442300
https://doi.org/10.1158/1078-0432.22442300
Autor:
Guido Kroemer, Maria Castedo, Jean-Charles Soria, Murat Saparbaev, Philippe Dessen, Catherine Brenner, Gen Sheng Wu, Kimitoshi Kohno, Parviz Behnam-Motlagh, Pauline Garcia, Abdul Qader Sukkurwala, Delphine Lissa, Cédric Oréar, Philippe Girard, Angélique Robin, Monique Talbot, David Pierre Enot, Justine Guegan, Ibtissam Talhaoui, Laura Senovilla, Oliver Kepp, Ken André Olaussen, Julien Adam, Lorenzo Galluzzi, Ilio Vitale, Judith Michels
PDF file - 490K, Supplementary Table S1. Systematic comparison of the effects of CDDP and PARP inhibitors on cancer cell lines used in this study. Supplementary Figure S1. Generation and characterization of CDDP-resistant human NSCLC cell clones. Sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65cc071c79c2ef3428fba45e85da2ba9
https://doi.org/10.1158/0008-5472.22399542.v1
https://doi.org/10.1158/0008-5472.22399542.v1
Autor:
Giorgia Guaitoli, Francesco Facchinetti, Juan David Flórez-Arango, Floriane Braye, Hayato Mizuta, Santiago Ponce-Aix, Damien Vasseur, Ken André Olaussen, Stefan Michiels, Mihaela Aldea, Jordi Remon, Fabrice Barlesi, Benjamin Besse, David Planchard, Luc Friboulet
Publikováno v:
Cancer Research. 83:3418-3418
Introduction: Advent of targeted therapies has deeply changed treatment of advanced oncogene-addicted non-small cell lung cancer (NSCLC), but development of resistance remains a main issue. Given the efficacy of next generation tyrosine kinase inhibi