Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Ken A. Olaussen"'
Autor:
Damien Vasseur, Ludovic Bigot, Kristi Beshiri, Juan Flórez-Arango, Francesco Facchinetti, Antoine Hollebecque, Lambros Tselikas, Mihaela Aldea, Felix Blanc-Durand, Anas Gazzah, David Planchard, Ludovic Lacroix, Noémie Pata-Merci, Catline Nobre, Alice Da Silva, Claudio Nicotra, Maud Ngo-Camus, Floriane Braye, Sergey I. Nikolaev, Stefan Michiels, Gérôme Jules-Clement, Ken André Olaussen, Fabrice André, Jean-Yves Scoazec, Fabrice Barlesi, Santiago Ponce, Jean-Charles Soria, Benjamin Besse, Yohann Loriot, Luc Friboulet
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Understanding the resistance mechanisms of tumor is crucial for advancing cancer therapies. The prospective MATCH-R trial (NCT02517892), led by Gustave Roussy, aimed to characterize resistance mechanisms to cancer treatments throu
Externí odkaz:
https://doaj.org/article/e6a5668f34d34175ab097af1e5bb22e4
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
PDF file - 81K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35eea7db712006912b959d23558ba756
https://doi.org/10.1158/1078-0432.22442309.v1
https://doi.org/10.1158/1078-0432.22442309.v1
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
XLS file - 15K, Mutations details
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16f7263fade1df2723063489e4d4c73
https://doi.org/10.1158/1078-0432.22442303
https://doi.org/10.1158/1078-0432.22442303
Autor:
Luc Friboulet, Christophe Massard, Ken A. Olaussen, Yohann Loriot, Rastislav Bahleda, Antoine Hollebecque, Francesco Facchinetti
Precision oncology relies on the identification of molecular alterations, responsible for tumor initiation and growth, which are suitable targets of specific inhibitors. The development of FGFR inhibitors represents an edifying example of the rapid e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29249be2f2ea25970a8a08725d5f64bb
https://doi.org/10.1158/1078-0432.c.6529607.v1
https://doi.org/10.1158/1078-0432.c.6529607.v1
Autor:
Luc Friboulet, Benjamin Besse, Jean-Charles Soria, Ken A. Olaussen, Christophe Massard, Fabrice Andre, Alexander M. Eggermont, Eric Angevin, Eric Solary, Lambros Tselikas, Thierry De Baere, Nathalie Auger, Catherine Richon, Ludovic Lacroix, Stefan Michiels, Maud Ngo-Camus, Claudio Nicotra, Antoine Hollebecque, Rastilav Bahleda, Gilles Vassal, Aurélie Abou Lovergne, Linda Mahjoubi, Pernelle Lavaud, Charles Naltet, Floriane Braye, Pauline Tesson, Justine Galissant, Dariia Samofalova, Olivier Deas, Karen Howarth, Tony Sourisseau, Jean-Yves Scoazec, Jean Paul Thiery, Rosa L. Frias, Ahsan Z. Rizvi, Ludovic Bigot, Anas Gazzah, David Planchard, Francesco Facchinetti, Laura Mezquita, Gonzalo Recondo
Supplementary Figure 3: NF2 deleterious mutations and sensitivity to lorlatinib (corresponding to main Figure 4).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295ddc322c4e352d2e365e9861f1b33b
https://doi.org/10.1158/1078-0432.22474059
https://doi.org/10.1158/1078-0432.22474059
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
PDF file - 171K, Frequencies of gain, or loss, according to ERCC1-IHC status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdb66dd10fdbfa4b2b139ff1ebdcfb8
https://doi.org/10.1158/1078-0432.22442312.v1
https://doi.org/10.1158/1078-0432.22442312.v1
Autor:
Luc Friboulet, Benjamin Besse, Jean-Charles Soria, Ken A. Olaussen, Christophe Massard, Fabrice Andre, Alexander M. Eggermont, Eric Angevin, Eric Solary, Lambros Tselikas, Thierry De Baere, Nathalie Auger, Catherine Richon, Ludovic Lacroix, Stefan Michiels, Maud Ngo-Camus, Claudio Nicotra, Antoine Hollebecque, Rastilav Bahleda, Gilles Vassal, Aurélie Abou Lovergne, Linda Mahjoubi, Pernelle Lavaud, Charles Naltet, Floriane Braye, Pauline Tesson, Justine Galissant, Dariia Samofalova, Olivier Deas, Karen Howarth, Tony Sourisseau, Jean-Yves Scoazec, Jean Paul Thiery, Rosa L. Frias, Ahsan Z. Rizvi, Ludovic Bigot, Anas Gazzah, David Planchard, Francesco Facchinetti, Laura Mezquita, Gonzalo Recondo
Purpose:Lorlatinib is a third-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor with proven efficacy in patients with ALK-rearranged lung cancer previously treated with first- and second-generation ALK inhibitors. Beside compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497a587b9ae25004327b21a79ff50bad
https://doi.org/10.1158/1078-0432.c.6528672
https://doi.org/10.1158/1078-0432.c.6528672
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
XLS file - 14K, List of Top 29 miRNA differentially expressed between the two groups ERCC1 positive / negative used for patients hierarchical clustering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d817e17f708fbba3777e72a3b7db8d3
https://doi.org/10.1158/1078-0432.22442306.v1
https://doi.org/10.1158/1078-0432.22442306.v1
Autor:
Luc Friboulet, Christophe Massard, Ken A. Olaussen, Yohann Loriot, Rastislav Bahleda, Antoine Hollebecque, Francesco Facchinetti
Phase I trials of selective FGFR inhibitors encompassing a dose-escalation phase and lacking a precise histologic/molecular selection (with the exception of Debio 1347)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278f26aa805d305c5621561b88ab88d9
https://doi.org/10.1158/1078-0432.22477271.v1
https://doi.org/10.1158/1078-0432.22477271.v1
Data from Molecular Characteristics of ERCC1-Negative versus ERCC1-Positive Tumors in Resected NSCLC
Autor:
Jean-Charles Soria, Fabrice André, Fabienne Dufour, Johanna Hasmats, Ludovic Lacroix, Philippe Girard, Pierre Validire, Benjamin Besse, Bastien Job, Vladimir Lazar, Nicolas Dorvault, Aïcha Goubar, Julien Adam, Stephan Vagner, Ken André Olaussen, Frédéric Commo, Daniel Barrios-Gonzales, Luc Friboulet
Purpose: Excision repair cross-complementation group 1 (ERCC1) is a protein involved in repair of DNA platinum adducts and stalled DNA replication forks. We and others have previously shown the influence of ERCC1 expression upon survival rates and be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200a3a66bcaaa0c46e55c241e42f6c42
https://doi.org/10.1158/1078-0432.c.6519074
https://doi.org/10.1158/1078-0432.c.6519074