Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ken A. Frankel"'
Autor:
Enrico Gratton, Stephanie J. Mihalik, Michael J. Bennett, Meghan Hauser, Aris Polyzos, Kelly S. Trego, Ken A. Frankel, Do Yup Lee, Ke Xu, Rupsa Datta, Cynthia T. McMurray, Jerry Vockley, Amy Holt, Helen Budworth, Pike Goldschmidt
Publikováno v:
Cell metabolism, vol 29, iss 6
The basis for region-specific neuronal toxicity in Huntington disease is unknown. Here, we show that region-specific neuronal vulnerability is a substrate-driven response in astrocytes. Glucose is low in HdhQ(150/150) animals, and astrocytes in each
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feccc747428cb8d2850116a7f9ae7972
https://escholarship.org/uc/item/7ff3q6v0
https://escholarship.org/uc/item/7ff3q6v0
Autor:
Steven D. Chang, Ken A. Frankel, Richard Levy, Mary L. Marcellus, Deborah L. Shuster, Michael P. Marks, Gary K. Steinberg
Publikováno v:
Neurologia medico-chirurgica. 38:200-207
Radiosurgery is effective in obliterating small arteriovenous malformations (AVMs), but less successful in thrombosing larger AVMs. This study reviewed patients who underwent surgical resection of their large AVMs following failed radiosurgical oblit
Autor:
Susan L. Bernstein, Ken A. Frankel, Cynthia T. McMurray, Do Yup Lee, Christie A. Canaria, Virginia Platt
Publikováno v:
Methods in Molecular Biology ISBN: 9781627034104
Methods Mol Biol
Methods Mol Biol
Many trinucleotide repeat disorders exhibit region-specific toxicity within tissues, the basis of which cannot be explained by traditional methods. For example, in Huntington's Disease (HD), the toxic disease-causing protein is ubiquitously expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf601ada1f1e6f8ef6c36f02daa40528
https://doi.org/10.1007/978-1-62703-411-1_14
https://doi.org/10.1007/978-1-62703-411-1_14
Publikováno v:
Tsutakawa, Susan E.; Hura, Greg L.; Frankel, Ken A.; Cooper, Priscilla K.; & Tainer, John A.(2006). Structural analysis of flexible proteins in solution by Small Angle X-ray Scattering combined with crystallography. Lawrence Berkeley National Laboratory. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/27r7m28b
In the last few years, SAXS of biological materials has been rapidly evolving and promises to move structural analysis to a new level. Recent innovations in SAXS data analysis allow ab initio shape predictions of proteins in solution. Furthermore, ex
Autor:
Gary K. Steinberg, Steven D. Chang, Mary L. Marcellus, Ken A. Frankel, Richard Levy, Michael P. Marks
Publikováno v:
Journal of neurosurgery. 84(6)
✓ Although radiosurgery is effective in obliterating small arteriovenous malformations (AVMs), it has a lower success rate for thrombosing larger AVMs. The authors surgically resected AVMs from 33 patients ranging in age from 7 to 64 years (mean 30