Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ken Takumi"'
Autor:
Keisuke Mori, Norio Iijima, Shimpei Higo, Satoko Aikawa, Izumi Matsuo, Ken Takumi, Atsuhiro Sakamoto, Hitoshi Ozawa
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87319 (2014)
BACKGROUND: We previously reported that sevoflurane anesthesia reversibly suppresses the expression of the clock gene, Period2 (Per2), in the mouse suprachiasmatic nucleus (SCN). However, the molecular mechanisms underlying this suppression remain un
Externí odkaz:
https://doaj.org/article/f8bc6b3c5ded489abd6f69616f1f01eb
Autor:
Megumi Anzai, Norio Iijima, Shimpei Higo, Ken Takumi, Izumi Matsuo, Keisuke Mori, Yumiko Ohe, Kana Kadota, Toshio Akimoto, Atsuhiro Sakamoto, Hitoshi Ozawa
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59454 (2013)
BACKGROUND: Our previous studies revealed that application of the inhalation anesthetic, sevoflurane, reversibly repressed the expression of Per2 in the mouse suprachiasmatic nucleus (SCN). We aimed to examine whether sevoflurane directly affects the
Externí odkaz:
https://doaj.org/article/0dae67df12b04e898be25fd18a3f48b0
Autor:
Yuji Tomori, Hirotaka Ishii, Shuji Hinuma, Hitoshi Ozawa, Ken Takumi, Shinro Takai, Norio Iijima
Publikováno v:
Acta Histochemica et Cytochemica
Liposomes, artificial phospholipid vesicles, have been developed as a non-viral drug delivery system to allow contained agents to be efficiently delivered to target sites via systemic circulation. Liposomes have been used as a gene transfer tool with
Publikováno v:
Histochemistry and Cell Biology. 148:289-298
We have newly developed a system that allows monitoring of the intensity of fluorescent signals from deep brains of rats transgenically modified to express enhanced green fluorescent protein (eGFP) via an optical fiber. One terminal of the optical fi
Publikováno v:
Acta Histochemica et Cytochemica
The neuropeptide kisspeptin plays an important role in fertility and the onset of puberty, stimulating gonadotropin-releasing hormone (GnRH) neurons to activate the hypothalamic-pituitary-gonadal axis. Several studies have demonstrated a morphologica
Publikováno v:
Neuroscience Letters. 531:40-45
Kisspeptin, a neuropeptide encoded by Kiss1 gene, plays pivotal roles in the regulation of reproductive function. Recently various stressors and stress-induced molecules such as corticotropin-releasing hormone (CRH) and corticosterone have been shown
Publikováno v:
Neuroscience research. 117
Insufficiency of thyroid hormones inhibits gonadotropin release and results in dysregulation of reproductive function, although the precise mechanism of this disrupted gonadotropin secretion remains unclear. Kisspeptin is a neuropeptide that strongly
Publikováno v:
The Journal of Physiological Sciences. 62:453-460
Kisspeptins, encoded by Kiss1 gene, play pivotal roles in the regulation of reproduction. Recently, several studies reported a sex difference in Kiss1 expression in the arcuate nucleus (ARC) during the neonatal period. In this study, we investigated
Autor:
Izumi Matsuo, Shimpei Higo, Shinji Nakagawa, Seiji Nagamoto, Atsuhiro Sakamoto, Ken Takumi, Satoko Aikawa, Norio Iijima, Yasufumi Shigeyoshi, Naoyuki Takashima, Megumi Anzai, Hitoshi Ozawa, Hirotaka Ishii
Publikováno v:
Neuroscience letters. 620
General anesthesia affects the expression of clock genes in various organs. Expression of Per2, a core component of the circadian clock, is markedly and reversibly suppressed by sevoflurane in the suprachiasmatic nucleus (SCN), and is considered to b
Publikováno v:
Journal of Molecular Neuroscience. 43:146-154
To investigate the reported discrepancy regarding the immunohistochemical expression of kisspeptin neurons, we produced a new antibody against synthetic peptide containing the same amino acid residual sequence as rat kisspeptin10. Although the antibo