Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ken, Arae"'
Autor:
Takafumi Numata, Masashi Ikutani, Ken Arae, Tatsukuni Ohno, Koki Okada, Takayuki Yoshimoto, Katsuko Sudo, Hajime Suto, Ko Okumura, Hirohisa Saito, Kazutoshi Harada, Susumu Nakae
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Mast cells (MCs) are tissue-resident cells of hematopoietic origin that play an important role in host’s defense mechanism against nematodes. However, excessive activation of these cells contributes to the development of certain allergic d
Externí odkaz:
https://doaj.org/article/83d53b6c13d247158b51514ad8b543e2
Autor:
Ken Arae, Masashi Ikutani, Kotaro Horiguchi, Sachiko Yamaguchi, Youji Okada, Hiroki Sugiyama, Keisuke Orimo, Hideaki Morita, Hajime Suto, Ko Okumura, Haruhiko Taguchi, Kenji Matsumoto, Hirohisa Saito, Katsuko Sudo, Susumu Nakae
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Exposure to various antigens derived from house dust mites (HDM) is considered to be a risk factor for development of certain allergic diseases such as atopic asthma, atopic dermatitis, rhinitis and conjunctivitis. Chitin is an insoluble pol
Externí odkaz:
https://doaj.org/article/b2ff8b41fa784b708de791905ef9f743
Autor:
Masato Tamari, Keisuke Orimo, Kenichiro Motomura, Ken Arae, Akio Matsuda, Susumu Nakae, Hirohisa Saito, Hideaki Morita, Kenji Matsumoto
Publikováno v:
Allergology International, Vol 67, Iss 3, Pp 380-387 (2018)
Background: Direct contact of food proteins with eczematous lesions is thought to be the main cause of epicutaneous sensitization. To further investigate the development and pathogenesis of food allergy in vivo, a good mouse model of epicutaneous sen
Externí odkaz:
https://doaj.org/article/88653586ed794c05b2229ac8404d4b15
Autor:
Ayako Takamori, Aya Nambu, Keiko Sato, Sachiko Yamaguchi, Kenshiro Matsuda, Takafumi Numata, Takeru Sugawara, Takamichi Yoshizaki, Ken Arae, Hideaki Morita, Kenji Matsumoto, Katsuko Sudo, Ko Okumura, Jiro Kitaura, Hiroshi Matsuda, Susumu Nakae
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract IL-31, which is a member of the IL-6 family of cytokines, is produced mainly by activated CD4+ T cells, in particular activated Th2 cells, suggesting a contribution to development of type-2 immune responses. IL-31 was reported to be increase
Externí odkaz:
https://doaj.org/article/132de0ad94d94b119863cbd4870bdb3d
Autor:
Kyoko Saito, Keisuke Orimo, Terufumi Kubo, Masato Tamari, Ayako Yamada, Kenichiro Motomura, Hiroki Sugiyama, Ryo Matsuoka, Naoko Nagano, Yuka Hayashi, Ken Arae, Mariko Hara, Masashi Ikutani, Tatsuki Fukuie, Katsuko Sudo, Akio Matsuda, Yukihiro Ohya, Shigeharu Fujieda, Hirohisa Saito, Susumu Nakae, Kenji Matsumoto, Cezmi A. Akdis, Hideaki Morita
Publikováno v:
Allergy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df8e1b0ef4f84dd52f22df14c695f7b2
https://doi.org/10.1111/all.15762
https://doi.org/10.1111/all.15762
Publikováno v:
Allergology International, Vol 62, Iss 1, Pp 13-20 (2013)
Interleukin-33 (IL-33), a member of the IL-1 cytokine family, is preferentially and constitutively expressed in epithelial cells, and it is especially localized in the cells' nucleus. The nuclear IL-33 is released by necrotic cells after tissue injur
Externí odkaz:
https://doaj.org/article/0aa57dd82bcc4c83af06c556849e5658
Autor:
Hajime Suto, Hirohisa Saito, Katsuko Sudo, Akira Matsuda, Susumu Nakae, Ken Arae, Hirotoshi Unno, Akio Matsuda, Masashi Ikutani, Ko Okumura, Kenji Matsumoto, Kenichiro Motomura, Masato Tamari, Hideaki Morita, Sumika Toyama
Publikováno v:
Biochemical and Biophysical Research Communications. 533:493-500
Silica crystals (silica), which are a major mineral component of volcanic ash and desert dust, contribute to the pathogenesis of pulmonary disorders such as asthma and fibrosis. Although administration of silica or sand dust to rodents exacerbates de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f35a52fa17644322a2117ceaf407a88
https://doi.org/10.1016/j.bbrc.2020.09.046
https://doi.org/10.1016/j.bbrc.2020.09.046
Autor:
Ryo MATSUOKA, Yuka Hayashi, Naoko Nagano, Hiroki Sugiyama, Ayako Yamada, Keisuke Orimo, Kenichiro Motomura, Masashi Ikutani, Ken Arae, Hirohisa Saito, Susumu Nakae, Kenji Matsumoto, Hideaki Morita
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46240222b62aa27f60f0d6b81da1cc3c
https://doi.org/10.1016/j.jaci.2022.12.311
https://doi.org/10.1016/j.jaci.2022.12.311
Autor:
Hiroki Sugiyama, Ayako Yamada, Masato Tamari, Keisuke Orimo, Kyoko Saito, Ryo Matsuoka, Naoko Nagano, Yuka Hayashi, Kenichiro Motomura, Masashi Ikutani, Ken Arae, Hirohisa Saito, Susumu Nakae, Kenji Matsumoto, Hideaki Morita
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca50c551b1daacd1dc91348bf0791a76
https://doi.org/10.1016/j.jaci.2022.12.009
https://doi.org/10.1016/j.jaci.2022.12.009
ST2 Requires Th2-, but Not Th17-, Type Airway Inflammation in Epicutaneously Antigen-Sensitized Mice
Autor:
Hideaki Morita, Ken Arae, Tatsukuni Ohno, Naoki Kajiwara, Keisuke Oboki, Akio Matsuda, Hajime Suto, Ko Okumura, Katsuko Sudo, Takao Takahashi, Kenji Matsumoto, Susumu Nakae
Publikováno v:
Allergology International, Vol 61, Iss 2, Pp 265-273 (2012)
Background: IL-33 is known to induce Th2-type cytokine production by various types of cells through its receptors, ST2 and IL-1RAcP. Polymorphism in the ST2 and/or IL-33 genes was found in patients with atopic dermatitis and asthma, implying that the
Externí odkaz:
https://doaj.org/article/37e0ba2f7cd843a18b856e0516ea8eb9