Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Kemp H. Kernstine"'
Autor:
Mitchell S. vonItzstein, Rong Lu, Kemp H. Kernstine, Ethan A. Halm, Shidan Wang, Yang Xie, David E. Gerber
Publikováno v:
Cancer Medicine, Vol 9, Iss 12, Pp 4137-4147 (2020)
Abstract Background Clinical outcomes for resected early‐stage non‐small cell lung cancer (NSCLC) are superior at high‐volume facilities, but reasons for these differences remain unclear. Understanding these differences and optimizing outcomes
Externí odkaz:
https://doaj.org/article/8abc7df798244a17abfe80ae09edb529
Lung Cancer: Over the course of the last decade, the treatment of lung cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of
Autor:
Mitchell S von Itzstein, Arjun Gupta, Kemp H Kernstine, Kristin C Mara, Sahil Khanna, David E Gerber
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231258 (2020)
INTRODUCTION:Advances in surgical techniques have improved clinical outcomes and decreased complications. At the same time, heightened attention to care quality has resulted in increased identification of hospital-acquired adverse events. We evaluate
Externí odkaz:
https://doaj.org/article/c6a6065b27b048bead91898bbe2e4b72
Data from Overexpression and Hypomethylation of Flap Endonuclease 1 Gene in Breast and Other Cancers
Autor:
Binghui Shen, Dongxin Lin, Kemp H. Kernstine, Wen Tan, Qin Huang, Dianke Yu, Huifang Dai, Ming Yang, Purnima Singh
Flap endonuclease 1 (FEN1) is a structure-specific nuclease best known for its critical roles in Okazaki fragment maturation, DNA repair, and apoptosis-induced DNA fragmentation. Functional deficiencies in FEN1, in the forms of somatic mutations and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0953f015098a2f46f4a429dbb83bfcea
https://doi.org/10.1158/1541-7786.c.6541473
https://doi.org/10.1158/1541-7786.c.6541473
Autor:
Binghui Shen, Dongxin Lin, Kemp H. Kernstine, Wen Tan, Qin Huang, Dianke Yu, Huifang Dai, Ming Yang, Purnima Singh
Supplementary Tables S1-S3 from Overexpression and Hypomethylation of Flap Endonuclease 1 Gene in Breast and Other Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da89ec73ec0175a35e78ddbd1f99c7d
https://doi.org/10.1158/1541-7786.22516749.v1
https://doi.org/10.1158/1541-7786.22516749.v1
Autor:
James T. Nawalaniec, Matthew Elson, Scott I. Reznik, Michael A. Wait, Matthias Peltz, Michael E. Jessen, Alejandra Madrigales, Jerzy Lysikowski, Kemp H. Kernstine
Publikováno v:
Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. 17:127-135
Objective: Our objective was to evaluate for any changes in quality or cost when robotic lung resection is used with significant trainee participation. Methods: All anatomic lung resections between January 2006 and June 2016 were identified from a pr
Autor:
Kemp H. Kernstine, Ralph J. DeBerardinis, Chyndhri Padmanabhan, Jessica Saltarski, Quyen N. Do, Ivan Pedrosa, Lorraine Pelosof, Chul Ahn, Rachael Skelton, David E. Gerber, Raja Reddy Kallem, Sahba Kasiri, Scott I. Reznik, Yin Xi, Farjana J. Fattah, Rolf A. Brekken, Richard D. Leff, Vaidehi Chembukar, William C. Putnam, James Kim, Robert E. Lenkinski, Brandon Faubert, Qing Yuan, Indhumathy Subramaniyan
Publikováno v:
Clin Cancer Res
Purpose: Itraconazole has been repurposed as an anticancer therapeutic agent for multiple malignancies. In preclinical models, itraconazole has antiangiogenic properties and inhibits Hedgehog pathway activity. We performed a window-of-opportunity tri
Autor:
David E. Gerber, Esra A. Akbay, Farjana J. Fattah, Kathryn H. Dao, Bipasha Mukherjee, Chao Xing, Amyn A. Habib, Boning Gao, Shanrong Zhang, Matthew E. Bender, Kemp H. Kernstine, Cheng Ming Chiang, Ke Gong, John D. Minna, Gao Guo, Michael Peyton, Dawen Zhao, Nishah Panchani, Adwait Amod Sathe, Sandeep Burma
Publikováno v:
Nature Cancer. 1:394-409
EGFR inhibition is an effective treatment in the minority of non-small cell lung cancer (NSCLC) cases harboring EGFR-activating mutations, but not in EGFR wild type (EGFRwt) tumors. Here, we demonstrate that EGFR inhibition triggers an antiviral defe
Autor:
Jose R. Torrealba, Christopher T. Hensley, Kemp H. Kernstine, Craig R. Malloy, Robert E. Lenkinski, Brandon Faubert, Quyen N. Do, Ling Cai, Thomas J. Rogers, Dwight H Oliver, Ralph J. DeBerardinis, Jason W Wachsmann
Publikováno v:
Ann Thorac Surg
Background In non-small cell lung cancer (NSCLC), 18fluoro-2-deoxyglucose–positron emission tomography (FDG-PET) assists in diagnosis, staging, and evaluating treatment response. One variable of FDG-PET, the maximum standard uptake value (SUVm), is
Autor:
Suzanne M. Dellaria, Jonathan Stubblefield, Kemp H. Kernstine, Alycia Wanat-Hawthorne, Isaac P. Lynch
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 33:776-780