Knowledge graphs facilitate prediction of drug response for acute myeloid leukemia

Autor: Qin, Guangrong, Zhang, Yue, Tyner, Jeffrey W., Kemp, Christopher J., Shmulevich, Ilya

Publikováno v: In iScience 20 September 2024 27(9)

Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition.

Autor: Stoll, Anna C.^1,2 (AUTHOR), Kemp, Christopher J.¹ (AUTHOR), Patterson, Joseph R.¹ (AUTHOR), Kubik, Michael¹ (AUTHOR), Kuhn, Nathan¹ (AUTHOR), Benskey, Matthew¹ (AUTHOR), Duffy, Megan F.¹ (AUTHOR), Luk, Kelvin C.³ (AUTHOR), Sortwell, Caryl E.¹ (AUTHOR) caryl.sortwell@gmail.com

Publikováno v: Journal of Neuroinflammation. 4/25/2024, Vol. 21 Issue 1, p1-17. 17p.

A functional module states framework reveals transcriptional states for drug and target prediction

Autor: Qin, Guangrong, Knijnenburg, Theo A., Gibbs, David L., Moser, Russell, Monnat, Raymond J., Jr., Kemp, Christopher J., Shmulevich, Ilya

Publikováno v: In Cell Reports 18 January 2022 38(3)

An expanded universe of cancer targets

Autor: Dancik, Vlado, Gill, Shubhroz, Hua, Bruce, Sharifnia, Tanaz, Viswanathan, Vasanthi, Zou, Yilong, Dela Cruz, Filemon, Kung, Andrew, Stockwell, Brent, Boehm, Jesse, Dempster, Josh, Manguso, Robert, Vazquez, Francisca, Cooper, Lee A.D., Du, Yuhong, Ivanov, Andrey, Lonial, Sagar, Moreno, Carlos S., Niu, Qiankun, Owonikoko, Taofeek, Ramalingam, Suresh, Reyna, Matthew, Zhou, Wei, Grandori, Carla, Shmulevich, Ilya, Swisher, Elizabeth, Cai, Jitong, Chan, Issac S., Dunworth, Matthew, Ge, Yuchen, Georgess, Dan, Grasset, Eloïse M., Henriet, Elodie, Knútsdóttir, Hildur, Lerner, Michael G., Padmanaban, Veena, Perrone, Matthew C., Suhail, Yasir, Tsehay, Yohannes, Warrier, Manisha, Morrow, Quin, Nechiporuk, Tamilla, Long, Nicola, Saultz, Jennifer, Kaempf, Andy, Minnier, Jessica, Tognon, Cristina E., Kurtz, Stephen E., Agarwal, Anupriya, Brown, Jordana, Watanabe-Smith, Kevin, Vu, Tania Q., Jacob, Thomas, Yan, Yunqi, Robinson, Bridget, Lind, Evan F., Kosaka, Yoko, Demir, Emek, Estabrook, Joseph, Grzadkowski, Michael, Nikolova, Olga, Chen, Ken, Deneen, Ben, Liang, Han, Bassik, Michael C., Bhattacharya, Asmita, Brennan, Kevin, Curtis, Christina, Gevaert, Olivier, Ji, Hanlee P., Karlsson, Kasper A.J., Karagyozova, Kremena, Lo, Yuan-Hung, Liu, Katherine, Nakano, Michitaka, Sathe, Anuja, Smith, Amber R., Spees, Kaitlyn, Wong, Wing Hing, Yuki, Kanako, Hangauer, Matt, Kaufman, Dan S., Balmain, Allan, Bollam, Saumya R., Chen, Wei-Ching, Fan, QiWen, Kersten, Kelly, Krummel, Matthew, Li, Yun Rose, Menard, Marie, Nasholm, Nicole, Schmidt, Christin, Serwas, Nina K., Yoda, Hiroyuki, Ashworth, Alan, Bandyopadhyay, Sourav, Bivona, Trevor, Eades, Gabriel, Oberlin, Stefan, Tay, Neil, Wang, Yuhao, Weissman, Jonathan, Hahn, William C., Bader, Joel S., Braun, Theodore P., Califano, Andrea, Clemons, Paul A., Druker, Brian J., Ewald, Andrew J., Fu, Haian, Jagu, Subhashini, Kemp, Christopher J., Kim, William, Kuo, Calvin J., McManus, Michael T., B. Mills, Gordon, Mo, Xiulei, Sahni, Nidhi, Schreiber, Stuart L., Talamas, Jessica A., Tamayo, Pablo, Tyner, Jeffrey W., Wagner, Bridget K., Weiss, William A., Gerhard, Daniela S.

Publikováno v: In Cell 4 March 2021 184(5):1142-1155

Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits

Autor: Gezer, Aysegul O., Kochmanski, Joseph, VanOeveren, Sarah E., Cole-Strauss, Allyson, Kemp, Christopher J., Patterson, Joseph R., Miller, Kathryn M., Kuhn, Nathan C., Herman, Danielle E., McIntire, Alyssa, Lipton, Jack W., Luk, Kelvin C., Fleming, Sheila M., Sortwell, Caryl E., Bernstein, Alison I.

Publikováno v: In Neurobiology of Disease July 2020 141