Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Kemmons A Tubbs"'
Autor:
Eric E Niederkofler, David A Phillips, Bryan Krastins, Vathany Kulasingam, Urban A Kiernan, Kemmons A Tubbs, Scott M Peterman, Amol Prakash, Eleftherios P Diamandis, Mary F Lopez, Dobrin Nedelkov
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81125 (2013)
Insulin-like growth factor 1 (IGF1) is an important biomarker of human growth disorders that is routinely analyzed in clinical laboratories. Mass spectrometry-based workflows offer a viable alternative to standard IGF1 immunoassays, which utilize var
Externí odkaz:
https://doaj.org/article/23c14967bec94eddb24220f0f7f531c7
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 3, Pp 630-639 (2003)
Novel mass spectrometric immunoassays (MSIAs) for the isolation and structural characterization of plasma apolipoprotein A-I (apoA-I), apoA-II, and apoE have been developed. The assays combine selective isolation of apolipoprotein species via affinit
Externí odkaz:
https://doaj.org/article/e1ab40796ebd4c7e8035e1af99888607
Publikováno v:
PROTEOMICS - CLINICAL APPLICATIONS. 2:1019-1024
The urine proteome (urineome) has become an ideal biological fluid for biomarker study and detection due to its rich protein content as well as its ease and abundance in collection. Protein variation in human plasma has been linked to the presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dde012c4bd3275f542d6740add5dc9
https://doi.org/10.1002/prca.200780118
https://doi.org/10.1002/prca.200780118
Publikováno v:
Molecular & Cellular Proteomics. 5:1811-1818
This review outlines the concept of population proteomics and its implication in the discovery and validation of cancer-specific protein modulations. Population proteomics is an applied subdiscipline of proteomics engaging in the investigation of hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f87348f5d05431a8b49e539ad4fc064c
https://doi.org/10.1074/mcp.r600006-mcp200
https://doi.org/10.1074/mcp.r600006-mcp200
Autor:
Allan L. Bieber, Kemmons A. Tubbs, Randall W. Nelson, Eric E. Niederkofler, Urban A. Kiernan, Dobrin Nedelkov
Publikováno v:
Analytical Chemistry. 78:3271-3276
This report addresses the need for additional assays for human resistin (hRES) by developing a rational progression of the mass spectrometric immunoassay to incorporate recombinant proteins. The recombinant-based hRES mass spectrometric immunoassay (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f683a157f9971d511f47f1c69bf3afa0
https://doi.org/10.1021/ac060013g
https://doi.org/10.1021/ac060013g
Autor:
Dobrin Nedelkov, Urban A. Kiernan, Allan L. Bieber, Randall W. Nelson, Eric E. Niederkofler, Kemmons A. Tubbs
Publikováno v:
PROTEOMICS. 5:5002-5007
A high-throughput affinity capture and reduction approach was developed for phenotype and post-translational modification analysis of a complexed globular protein, haptoglobin (Hp), directly from human plasma. Hp was selectively retrieved utilizing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808ea4e5b7800205176070aed8dfb1d0
https://doi.org/10.1002/pmic.200500176
https://doi.org/10.1002/pmic.200500176
Publikováno v:
Proceedings of the National Academy of Sciences. 102:10852-10857
Plasma proteins represent an important part of the human proteome. Although recent proteomics research efforts focus largely on determining the overall number of proteins circulating in plasma, it is equally important to delineate protein variations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c8ec8563a756edf80a0e6820e75a3c
https://doi.org/10.1073/pnas.0500426102
https://doi.org/10.1073/pnas.0500426102
Publikováno v:
Journal of Proteome Research. 3:851-855
Reported in this work are the development of mass spectrometric immunoassay (MSIA) devices and methods for the qualitative analysis of IGF-1 and -2, and the rigorous quantification of IGF-1 from human plasma. A method involving addition of SDS in mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fc34dc7d718ff970eeea22d0dd3d86
https://doi.org/10.1021/pr0499388
https://doi.org/10.1021/pr0499388
Publikováno v:
Molecular & Cellular Proteomics. 3:266-272
An alkaline phosphatase-bioreactive probe, in which the enzyme is covalently bound to the mass spectrometry target, has been developed for studies of phosphoproteins. The bioreactive probe was used in combination with affinity capture and matrix-assi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdbdf399db2531cf9186dba3bde3cab6
https://doi.org/10.1074/mcp.t300008-mcp200
https://doi.org/10.1074/mcp.t300008-mcp200
High-Throughput Comprehensive Analysis of Human Plasma Proteins: A Step toward Population Proteomics
Publikováno v:
Analytical Chemistry. 76:1733-1737
A high-throughput (HT) comprehensive analysis approach was developed for assaying proteins directly from human plasma. Proteins were selectively retrieved, by utilizing antibodies immobilized within affinity pipet tips, and eluted onto enzymatically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e915d04f7928c171630b12b063fcdeec
https://doi.org/10.1021/ac035105+
https://doi.org/10.1021/ac035105+