Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kemal Ugur Tufekci"'
Autor:
Deniz Ceylan, Bilge Karacicek, Kemal Ugur Tufekci, Izel Cemre Aksahin, Sevin Hun Senol, Sermin Genc
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundMood disorders are common disabling psychiatric disorders caused by both genetic and environmental factors. Mitochondrial DNA (mtDNA) modifications and epigenetics are promising areas of research in depression since mitochondrial dysfunctio
Externí odkaz:
https://doaj.org/article/843ab8a5d51d4acfa150269feea25d4d
Autor:
Kemal Ugur Tufekci, Jens Allmer, Kürşat Bora Çarman, Erhan Bayram, Yasemin Topçu, Semra Hız, Şermin Genç, Uluç Yiş
Publikováno v:
Neurological Sciences and Neurophysiology, Vol 38, Iss 3, Pp 166-172 (2021)
Background: Subacute sclerosing panencephalitis (SSPE) is a chronic, progressive disease caused by a persistent infection of the measles virus. Despite extensive efforts, the exact neurodegeneration mechanism in SSPE remains unknown. MicroRNAs (miRNA
Externí odkaz:
https://doaj.org/article/891baafafa2b4e7991bbc907ee4119b3
Autor:
Bora Tastan, Burak I. Arioz, Kemal Ugur Tufekci, Emre Tarakcioglu, Ceren Perihan Gonul, Kursad Genc, Sermin Genc
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
NLRP3 inflammasome activation contributes to several pathogenic conditions, including lipopolysaccharide (LPS)-induced sickness behavior characterized by reduced mobility and depressive behaviors. Dimethyl fumarate (DMF) is an immunomodulatory and an
Externí odkaz:
https://doaj.org/article/b60a1794759e426ca70953d604e6e91d
Autor:
Melis Olcum, Kemal Ugur Tufekci, Devrim Yagmur Durur, Bora Tastan, Irem Nur Gokbayrak, Kursad Genc, Sermin Genc
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 745 (2021)
Ethyl pyruvate is a molecule with anti-inflammatory and pro-metabolic effects. Ethyl pyruvate has been shown to ameliorate the clinical and pathological findings of neurodegenerative diseases such as Alzheimer’s and Parkinson’s Diseases in rodent
Externí odkaz:
https://doaj.org/article/5d1033071eca4fea9df271ade90b7895
Autor:
Burak I. Arioz, Bora Tastan, Emre Tarakcioglu, Kemal Ugur Tufekci, Melis Olcum, Nevin Ersoy, Alper Bagriyanik, Kursad Genc, Sermin Genc
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Inflammation is a crucial component of various stress-induced responses that contributes to the pathogenesis of major depressive disorder (MDD). Depressive-like behavior (DLB) is characterized by decreased mobility and depressive behavior that occurs
Externí odkaz:
https://doaj.org/article/24e7f872c8254d2b95f741e379e21522
Autor:
Kemal Ugur Tufekci, Ufuk Vurgun, Onur Yigitaslan, Pembe Keskinoglu, Erdem Yaka, Kursad Kutluk, Sermin Genc
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), which is TNF receptor superfamily member, contributes to several diseases pathogenesis. The aim of this research was to investigate the relevance of serum TRAIL protein levels and
Externí odkaz:
https://doaj.org/article/878fd79b38664159a7890476d028e35d
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Sulforaphane (SFN) is a natural product with cytoprotective, anti-inflammatory, and antioxidant effects. In this study, we evaluated the mechanisms of its effects on lipopolysaccharide (LPS)-induced cell death, inflammation, oxidative stress, and pol
Externí odkaz:
https://doaj.org/article/b017b92d653b47d983bbbb44564e1cd6
Publikováno v:
Parkinson's Disease, Vol 2011 (2011)
Mitochondrial dysfunction is a prominent feature of various neurodegenerative diseases as strict regulation of integrated mitochondrial functions is essential for neuronal signaling, plasticity, and transmitter release. Many lines of evidence suggest
Externí odkaz:
https://doaj.org/article/c6cc516e34374aacb9a9429d875f3753
Publikováno v:
Parkinson's Disease, Vol 2011 (2011)
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra. Although the exact cause of the dopaminergic neurodegeneration remains elusive, recent postmor
Externí odkaz:
https://doaj.org/article/db155454d1354b98b592dcd27dd3abd3
Publikováno v:
Autoimmune Diseases, Vol 2011 (2011)
MicroRNAs (miRNAs) have recently emerged as a new class of modulators of gene expression. miRNAs control protein synthesis by targeting mRNAs for translational repression or degradation at the posttranscriptional level. These noncoding RNAs are endog
Externí odkaz:
https://doaj.org/article/b6313f81841443889276f9540a612aac