Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kemal İnecik"'
Autor:
Jacob D. Muscato, Heidi G. Morris, Aaron Mychack, Mithila Rajagopal, Vadim Baidin, Anthony R. Hesser, Wonsik Lee, Kemal İnecik, Laura J. Wilson, Christina M. Kraml, Timothy C. Meredith, Suzanne Walker
Publikováno v:
Journal of the American Chemical Society. 144:3696-3705
Synthetic lethality occurs when inactivation of two genes is lethal but inactivation of either single gene is not. This phenomenon provides an opportunity for efficient compound discovery. Using differential growth screens, one can identify biologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb3bd5b7cccbd32bb847fcd9af6beff
https://doi.org/10.1021/jacs.1c12697
https://doi.org/10.1021/jacs.1c12697
Autor:
Elisabetta Cacace, Vladislav Kim, Michael Knopp, Manuela Tietgen, Amber Brauer-Nikonow, Kemal Inecik, André Mateus, Alessio Milanese, Marita Torrissen Mårli, Karin Mitosch, Joel Selkrig, Ana Rita Brochado, Oscar P. Kuipers, Morten Kjos, Georg Zeller, Mikhail M. Savitski, Stephan Göttig, Wolfgang Huber, Athanasios Typas
Drug combinations present a powerful strategy to tackle antimicrobial resistance, but have not been systematically tested in many bacterial species. Here, we used an automated high-throughput setup to profile ∼ 8000 combinations between 65 antibact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69940cd54719419b5b92db68ebc2407d
https://doi.org/10.1101/2022.12.23.521747
https://doi.org/10.1101/2022.12.23.521747
Single-cell multimodal profiling provides a high-resolution view of cellular information. Recently, multimodal profiling approaches have been coupled with CRISPR technologies to perform pooled screens of single or combinatorial perturbations. This op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::649b7b133d1409495073ccb7a6689ef4
https://doi.org/10.1101/2022.07.08.499049
https://doi.org/10.1101/2022.07.08.499049