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Akademický článek

Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation

Autor: Ying Wu, Yu-Mei Chang, Gerry Polton, Anneliese J. Stell, Balazs Szladovits, Michael Macfarlane, Laureen M. Peters, Simon L. Priestnall, Nicholas J. Bacon, Kelvin Kow, Sarah Stewart, Eshita Sharma, Michelle R. Goulart, John Gribben, Dong Xia, Oliver A. Garden

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs. Two DLBCL subtypes based on cell of origin are generally recognized, germinal center B (GCB)-like and activated B cell (A

Externí odkaz: https://doaj.org/article/19bfc687a13446c29920cc42a3f1668d

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Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation

Autor: Oliver A. Garden, Michelle R. Goulart, Ying Wu, Yu-Mei Chang, Sarah Stewart, John G. Gribben, Laureen M. Peters, Anneliese Stell, Kelvin Kow, Nicholas J. Bacon, Dong Xia, Gerry Polton, Balazs Szladovits, Simon L. Priestnall, Michael Macfarlane, Eshita Sharma

Publikováno v: Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d867f8a3472fa5383ba460ff24ad3153
https://doi.org/10.3389/fonc.2020.00307

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Plasma ammonia concentration after L-asparaginase therapy in 27 dogs with high-grade lymphoma or leukemia

Autor: Kelvin Kow, Christine E. Fahey, Amandine Lejeune, Rowan J. Milner, Kimberly A. Wirth, Abbie L. Speas, Sarah E. Lyles

Publikováno v: Journal of Veterinary Emergency and Critical Care. 28:130-139

Objectives To establish the occurrence of increased plasma ammonia concentration after L-asparaginase (L-asp) administration in dogs with high-grade lymphoma or leukemia; to identify risk factors for the development of hyperammonemia after L-asp admi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b418dbb2583becbbac0e0b3b09e3aaa2
https://doi.org/10.1111/vec.12695

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Clinical Response and Adverse Event Profile of Bleomycin Chemotherapy for Canine Multicentric Lymphoma

Autor: Carlos H. de Mello Souza, Ashley A. Smith, Rowan J. Milner, Kelvin Kow, Amandine Lejeune

Publikováno v: Journal of the American Animal Hospital Association. 53:128-134

Although canine multicentric lymphoma is initially responsive to multidrug chemotherapy, resistance and relapse create a need for novel chemotherapeutics. Bleomycin is an antitumor antibiotic with a minimal adverse event profile; though commonly used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c11dc9439d668e90033df0dd45890e
https://doi.org/10.5326/jaaha-ms-6598

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Retrospective Evaluation of Whole Body Computed Tomography for Tumor Staging in Dogs with Primary Appendicular Osteosarcoma

Autor: Jessica L. Talbott, Sarah E. Boston, Kelvin Kow, Jorge A. Hernandez, Amandine Lejeune, Carlos H. de Mello Souza, Rowan J. Milner, Nicholas J. Bacon

Publikováno v: Veterinary Surgery. 46:75-80

Objective To evaluate whole body computed tomography (CT) for staging canine appendicular osteosarcoma. Study Design Retrospective case series. Animals Client-owned dogs diagnosed with appendicular osteosarcoma (n=39). Methods Medical records for cli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7545fbf69d2a3fc5a72356cb343323a6
https://doi.org/10.1111/vsu.12579

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ASSOCIATION BETWEEN COMPUTED TOMOGRAPHIC CHARACTERISTICS AND FRACTURES FOLLOWING STEREOTACTIC RADIOSURGERY IN DOGS WITH APPENDICULAR OSTEOSARCOMA

Autor: Francis J. Bova, Kimberly A. Wirth, Atchar Sudhyadhom, Daniel J VanderHart, Rowan J. Milner, Kelvin Kow, James P. Farese, Qi An, Lyndsay Kubicek, Myron Chang, Nicholas J. Bacon

Publikováno v: Veterinary Radiology & Ultrasound. 57:321-330

The objective of this observational, descriptive, retrospective study was to report CT characteristics associated with fractures following stereotactic radiosurgery in canine patients with appendicular osteosarcoma. Medical records (1999 and 2012) of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c0f32067ca8c3ad69b0c60399ef548c
https://doi.org/10.1111/vru.12351

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OUTCOMES AND PROGNOSTIC FACTORS ASSOCIATED WITH CANINE SINONASAL TUMORS TREATED WITH CURATIVE INTENT CONE-BASED STEREOTACTIC RADIOSURGERY (1999-2013)

Autor: Rowan J. Milner, James P. Farese, Leslie E. Fox, Kristen Cooke, Nicholas J. Bacon, Kelvin Kow, Qi An, Myron Chang, Lyndsay Kubicek, David M. Lurie

Publikováno v: Veterinary Radiology & Ultrasound. 57:331-340

Stereotactic radiosurgery (SRS) is a relatively new therapeutic option in veterinary oncology. The role of this modality has not been extensively evaluated for the use in canine nasal tumors. The objective of this retrospective, observational study w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2806ce3d8c36eb09207a26a01d5c793
https://doi.org/10.1111/vru.12349

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In vitroeffects ofYunnan Baiyaoon canine hemangiosarcoma cell lines

Autor: Rowan J. Milner, Kimberly A. Wirth, Kelvin Kow, Nicholas J. Bacon, Marc E. Salute

Publikováno v: Veterinary and Comparative Oncology. 14:281-294

Yunnan Baiyao is a Chinese herbal medicine that has been utilized for its anti-inflammatory, haemostatic, wound healing and pain relieving properties in people. It has been utilized in the veterinary profession to control bleeding in dogs with hemang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ed25456707edfc85f43722eb9f1342
https://doi.org/10.1111/vco.12100

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