Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kelvin K, Hui"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Excitatory-inhibitory (E-I) imbalance has been shown to contribute to the pathogenesis of a wide range of neurodevelopmental disorders including autism spectrum disorders, epilepsy, and schizophrenia. GABA neurotransmission, the principal inhibitory
Externí odkaz:
https://doaj.org/article/8905461c1ed14815b16635a00f95b989
Autor:
Ryo Endo, Yi-Kai Chen, John Burke, Noriko Takashima, Nayan Suryawanshi, Kelvin K. Hui, Tatsuhiko Miyazaki, Motomasa Tanaka
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Ribosome-associated quality control (RQC) pathway is responsible for degradation of nascent polypeptides in aberrantly stalled ribosomes, and its defects may lead to neurological diseases. However, the underlying molecular mechanism of how RQC dysfun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be1954ec8e269f06c57358517f1447c7
https://doi.org/10.1073/pnas.2211522120
https://doi.org/10.1073/pnas.2211522120
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 680 (2019)
De novo protein synthesis by the ribosome and its multitude of co-factors must occur in a tightly regulated manner to ensure that the correct proteins are produced accurately at the right time and, in some cases, also in the proper location. With nov
Externí odkaz:
https://doaj.org/article/882fb54101384f228998c3af82e2c627
Autor:
Kelvin K, Hui, Maya, Latif, Chesa Dojo, Soeandy, Shudi, Huang, Christopher E, Rodgers, Andrew J, Elia, Jeffrey T, Henderson
Publikováno v:
Experimental Neurology. 351:114010
Cisplatin is a member of a widely utilized class of chemotherapeutic agent that initiates DNA damage response, cell cycle arrest, and p53-dependent apoptotic cell death in concert with DNA‑platinum adduct formation. While normal programmed cell dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545f435b0bf15f62714ca0cb6d2d7569
https://doi.org/10.1016/j.expneurol.2022.114010
https://doi.org/10.1016/j.expneurol.2022.114010
Autor:
Kelvin K, Hui, Noriko, Takashima, Akiko, Watanabe, Thomas E, Chater, Hiroshi, Matsukawa, Yoko, Nekooki-Machida, Per, Nilsson, Ryo, Endo, Yukiko, Goda, Takaomi C, Saido, Takeo, Yoshikawa, Motomasa, Tanaka
Publikováno v:
Science Advances
Autophagy regulates social behaviors by affecting the ability of brain cells to receive inhibitory signaling.
Dysfunctional mTOR signaling is associated with the pathogenesis of neurodevelopmental and neuropsychiatric disorders. However, it is u
Dysfunctional mTOR signaling is associated with the pathogenesis of neurodevelopmental and neuropsychiatric disorders. However, it is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6a0b538f2b0b27a163929f1e31d486a
https://pubmed.ncbi.nlm.nih.gov/30989111
https://pubmed.ncbi.nlm.nih.gov/30989111
CDKL5 regulates p62-mediated selective autophagy and confers protection against neurotropic viruses.
Autor:
Thinwa JW; Department of Internal Medicine.; Department of Microbiology., Zou Z; Department of Internal Medicine., Parks E; Department of Cell Biology, and., Sebti S; Department of Internal Medicine., Hui K; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan., Wei Y; Cancer Research Institute, Guangzhou Medical University, Guangzhou, China., Goodarzi M; Department of Immunology, and., Singh V; Department of Immunology, and., Urquhart G; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Jewell JL; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Pfeiffer JK; Department of Microbiology., Levine B; Department of Internal Medicine.; Department of Microbiology.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Reese TA; Department of Microbiology.; Department of Immunology, and., Shiloh MU; Department of Internal Medicine.; Department of Microbiology.
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2024 Jan 02; Vol. 134 (1). Date of Electronic Publication: 2024 Jan 02.
Autor:
Hui K; Laboratory for Protein Conformation Diseases, RIKEN Center for Brain Science, Japan., Katayama Y; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Japan., Nakayama KI; Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Japan., Nomura J; Laboratory for Mental Biology, RIKEN Center for Brain Science, Japan. Electronic address: jun.nomura@riken.jp., Sakurai T; Medical Innovation Center Kyoto University Graduate School of Medicine, Japan. Electronic address: sakurai@tk.med.kyoto-u.ac.jp.
Publikováno v:
Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2020 Mar; Vol. 110, pp. 77-91. Date of Electronic Publication: 2018 Nov 22.
Autor:
Jacobs B; Social Health Protection Programme, Deutsche Gesellschaft für Internationale Zusammenarbeit (GiZ), c/o NIPH, No.2, Street 289, Khan Toul Kork, P.O. Box 1238, Phnom Penh, Cambodia. bart.jacobs@giz.de.; Social Health Protection Network P4H, Phnom Penh, Cambodia. bart.jacobs@giz.de., Hui K; Social Health Protection Programme, Deutsche Gesellschaft für Internationale Zusammenarbeit (GiZ), c/o NIPH, No.2, Street 289, Khan Toul Kork, P.O. Box 1238, Phnom Penh, Cambodia., Lo V; Department of Planning and Health Information, Ministry of Health, Phnom Penh, Cambodia., Thiede M; Scenarium Group GmbH, Berlin, Germany., Appelt B; Social Health Protection Programme, Deutsche Gesellschaft für Internationale Zusammenarbeit (GiZ), c/o NIPH, No.2, Street 289, Khan Toul Kork, P.O. Box 1238, Phnom Penh, Cambodia., Flessa S; Department of General Business Administration and Health Care Management, University of Greifswald, Greifswald, Germany.
Publikováno v:
Health economics review [Health Econ Rev] 2019 Oct 30; Vol. 9 (1), pp. 29. Date of Electronic Publication: 2019 Oct 30.
Autor:
Nilsson P; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako, Saitama, Japan; Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden. Electronic address: per-nilsson@brain.riken.jp., Sekiguchi M; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako, Saitama, Japan., Akagi T; Support Unit for Animal Resources Development, RIKEN Brain Science Institute, Wako, Saitama, Japan., Izumi S; Department of Cell Biology, Unit of Basic Medical Sciences, Nagasaki University, Nagasaki, Japan., Komori T; Department of Cell Biology, Unit of Basic Medical Sciences, Nagasaki University, Nagasaki, Japan., Hui K; Laboratory for Protein Conformation Diseases, RIKEN Brain Science Institute, Wako, Saitama, Japan., Sörgjerd K; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako, Saitama, Japan., Tanaka M; Laboratory for Protein Conformation Diseases, RIKEN Brain Science Institute, Wako, Saitama, Japan., Saito T; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako, Saitama, Japan., Iwata N; Department of Biotechnology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan., Saido TC; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako, Saitama, Japan.
Publikováno v:
The American journal of pathology [Am J Pathol] 2015 Feb; Vol. 185 (2), pp. 305-13. Date of Electronic Publication: 2014 Nov 26.
Autor:
Nilsson P; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. Electronic address: per-nilsson@brain.riken.jp., Loganathan K, Sekiguchi M, Matsuba Y, Hui K, Tsubuki S, Tanaka M, Iwata N, Saito T, Saido TC
Publikováno v:
Cell reports [Cell Rep] 2013 Oct 17; Vol. 5 (1), pp. 61-9. Date of Electronic Publication: 2013 Oct 03.