Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kelvin G. K. Goh"'
Autor:
Nguyen Thi Khanh Nhu, M. Arifur Rahman, Kelvin G. K. Goh, Seung Jae Kim, Minh-Duy Phan, Kate M. Peters, Laura Alvarez-Fraga, Steven J. Hancock, Chitra Ravi, Timothy J. Kidd, Matthew J. Sullivan, Katharine M. Irvine, Scott A. Beatson, Matthew J. Sweet, Adam D. Irwin, Jana Vukovic, Glen C. Ulett, Sumaira Z. Hasnain, Mark A. Schembri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Bacteria adapt to selective pressure in their immediate environment in multiple ways. One mechanism involves the acquisition of independent mutations that disable or modify a key pathway, providing a signature of adaptation via convergent ev
Externí odkaz:
https://doaj.org/article/0c835c379e9d49008c3aba49b38fd4c2
Autor:
Matthew J. Sullivan, Darren Prince, Kelvin G. K. Goh, Lahiru Katupitiya, Dean Gosling, Michael R. Crowley, David K. Crossman, Glen C. Ulett
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Streptococcus agalactiae, also known as Group B Streptococcus (GBS) is a frequent cause of infections, including bacteraemia and other acute diseases in adults and immunocompromised individuals. We developed a novel system to study GBS withi
Externí odkaz:
https://doaj.org/article/ba104a9df20644099df98bfad98b3b28
Autor:
Brian R. Varghese, Kelvin G. K. Goh, Devika Desai, Dhruba Acharya, Collin Chee, Matthew J. Sullivan, Glen C. Ulett
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Streptococcus agalactiae, also known as group B Streptococcus, is an important human and animal pathogen. Zinc (Zn) is an essential trace element for normal bacterial physiology but intoxicates bacteria at high concentrations. Molecular systems for Z
Externí odkaz:
https://doaj.org/article/7317dbff37894546a38d7dc6c4ae4c47
Autor:
Matthew J. Sullivan, Kelvin G. K. Goh, Ruby Thapa, Debasish Chattopadhyay, Deepak S. Ipe, Benjamin L. Duell, Lahiru Katupitiya, Dean Gosling, Dhruba Acharya, Glen C. Ulett
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 3015-3027 (2021)
Streptococcus agalactiae glyceraldehyde 3-phosphate dehydrogenase (GAPDH), encoded by gapC, is a glycolytic enzyme that is associated with virulence and immune-mediated protection. However, the role of GAPDH in cellular cytokine responses to S. agala
Externí odkaz:
https://doaj.org/article/75affdcbde0645aa8fa80d903f557a0a
Autor:
Laura Alvarez-Fraga, Minh-Duy Phan, Kelvin G. K. Goh, Nguyen Thi Khanh Nhu, Steven J. Hancock, Luke P. Allsopp, Kate M. Peters, Brian M. Forde, Leah W. Roberts, Matthew J. Sullivan, Makrina Totsika, Scott A. Beatson, Glen C. Ulett, Mark A. Schembri
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Many antibiotic resistant uropathogenic Escherichia coli (UPEC) strains belong to clones defined by their multilocus sequence type (ST), with ST131 being the most dominant. Although we have a good understanding of resistance development to f
Externí odkaz:
https://doaj.org/article/604971ebb7e74b8980f09a7b03594636
Autor:
Frank Stadler, Talia Arjona, Glenn Beaumont, Charlotte Bradley, Alyssa Budd, Pedro Busana, Mathew Clatworthy, Jodie Fitz-Gibbon, Kelvin G. K. Goh, Matt Hayes, Kylie Heather, Aisha Lawton, Mike McAuley, Sarah Onoprienko, Aliana Rogers, Tiana Schimpf, Matthew J. Sullivan, Glen C. Ulett, Jessica Warren, Bridget Woodman, Zac Zerafa
Publikováno v:
Citizen Science: Theory and Practice, Vol 6, Iss 1 (2021)
This case study describes how high school students can participate in research, development, and testing of real-life solutions for society’s most intractable problems. In modern warfare, civilians make up most of the casualties, and conflict-affec
Externí odkaz:
https://doaj.org/article/c04101a0ea8b4c8392e5954f7a4b64fd
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Streptococcus agalactiaestreptococcus
Externí odkaz:
https://doaj.org/article/9bd1a11a484748df851d7a2e73df2362
Autor:
Dhruba Acharya, Matthew J. Sullivan, Benjamin L. Duell, Kelvin G. K. Goh, Lahiru Katupitiya, Dean Gosling, Michelle N. Chamoun, Asha Kakkanat, Debasish Chattopadhyay, Michael Crowley, David K. Crossman, Mark A. Schembri, Glen C. Ulett
Publikováno v:
mSphere, Vol 4, Iss 6 (2019)
ABSTRACT Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) engages interleukin-10 (IL-10) as an early innate immune response to regulate inflammation and promote the control of bladder infection. However, the mechanism of
Externí odkaz:
https://doaj.org/article/930a17e042a7487b9dc2d1c81b69a481
Publikováno v:
mSphere, Vol 4, Iss 4 (2019)
ABSTRACT Proteins secreted by the type V secretion system possess multiple functions, including the capacity to mediate adhesion, aggregation, and biolfilm formation. The type V secretion system can be divided into five subclasses, one of which is th
Externí odkaz:
https://doaj.org/article/5a2bce43cc6740758735a697a788792f
Autor:
Carrie F. Coggon, Andrew Jiang, Kelvin G. K. Goh, Ian R. Henderson, Mark A. Schembri, Timothy J. Wells
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Uropathogenic Escherichia coli (UPEC) is the most common cause of urinary tract infection, which in some patients can develop into life-threatening urosepsis. Serum resistance is a key virulence trait of strains that cause urosepsis. Recentl
Externí odkaz:
https://doaj.org/article/ccf7eefeb9d04f8d85e7d69f24c6a4cb