Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Keltouma DRIOUCH"'
Autor:
Rania El-Botty, Ludivine Morriset, Elodie Montaudon, Zakia Tariq, Anne Schnitzler, Marina Bacci, Nicla Lorito, Laura Sourd, Léa Huguet, Ahmed Dahmani, Pierre Painsec, Heloise Derrien, Sophie Vacher, Julien Masliah-Planchon, Virginie Raynal, Sylvain Baulande, Thibaut Larcher, Anne Vincent-Salomon, Guillaume Dutertre, Paul Cottu, Géraldine Gentric, Fatima Mechta-Grigoriou, Scott Hutton, Keltouma Driouch, Ivan Bièche, Andrea Morandi, Elisabetta Marangoni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability in most patients with estrogen receptor positive breast cancers (ER + BC). By genomic and metabolomics analyses of patients’ tumours, metastasis-de
Externí odkaz:
https://doaj.org/article/b26393ab46f442b18957dda9286c9e24
Autor:
Florian Bonin, Aurélie Chiche, Zakia Tariq, Paula Azorin, Sébastien Nola, Rosette Lidereau, Keltouma Driouch
Publikováno v:
Cancer Communications, Vol 42, Iss 10, Pp 1036-1040 (2022)
Externí odkaz:
https://doaj.org/article/a057b868a2e84a0c83132b2bc0c86f96
Autor:
Elizabeth Santana dos Santos, Amanda B. Spurdle, Dirce M. Carraro, Adrien Briaux, Melissa Southey, Giovana Torrezan, Ambre Petitalot, Raphael Leman, Philippe Lafitte, kConFab Investigators, Didier Meseure, Keltouma Driouch, Lucy Side, Carole Brewer, Sarah Beck, Athalie Melville, Alison Callaway, Françoise Revillion, Maria A. A. Koike Folgueira, Michael T. Parsons, Heather Thorne, Anne Vincent-Salomon, Dominique Stoppa-Lyonnet, Ivan Bieche, Sandrine M. Caputo, Etienne Rouleau
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract At least 10% of the BRCA1/2 tests identify variants of uncertain significance (VUS) while the distinction between pathogenic variants (PV) and benign variants (BV) remains particularly challenging. As a typical tumor suppressor gene, the ina
Externí odkaz:
https://doaj.org/article/11725e206c6145aaaf00ff5e47624a06
Autor:
Céline Callens, Keltouma Driouch, Anaïs Boulai, Zakia Tariq, Aurélie Comte, Frédérique Berger, Lisa Belin, Ivan Bièche, Vincent Servois, Patricia Legoix, Virginie Bernard, Sylvain Baulande, Walid Chemlali, François-Clément Bidard, Virginie Fourchotte, Anne Vincent- Salomon, Etienne Brain, Rosette Lidereau, Thomas Bachelot, Mahasti Saghatchian, Mario Campone, Sylvie Giacchetti, Brigitte Sigal Zafrani, Paul Cottu
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-15 (2021)
Abstract Background Prognosis evaluation of advanced breast cancer and therapeutic strategy are mostly based on clinical features of advanced disease and molecular profiling of the primary tumor. Very few studies have evaluated the impact of metastat
Externí odkaz:
https://doaj.org/article/ad1f3e2cf70f4b9695dd17547b4a898c
Kindlin‐1 modulates the EGFR pathway and predicts sensitivity to EGFR inhibitors across cancer types
Autor:
Paula Azorin, Florian Bonin, Zakia Tariq, Ambre Petitalot, Florence Coussy, Elisabetta Marangoni, Veronique Becette, Yves Denoux, Anne Vincent‐Salomon, Christophe Le Tourneau, Linda Larbi Cherif, Jerzy Klijanienko, Maud Kamal, Ivan Bièche, Rosette Lidereau, Keltouma Driouch
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 4, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/c28e054e76624d3fa1b78ff2cc145137
Autor:
Elodie Montaudon, Joanna Nikitorowicz-Buniak, Laura Sourd, Ludivine Morisset, Rania El Botty, Léa Huguet, Ahmed Dahmani, Pierre Painsec, Fariba Nemati, Sophie Vacher, Walid Chemlali, Julien Masliah-Planchon, Sophie Château-Joubert, Camilla Rega, Mariana Ferreira Leal, Nikiana Simigdala, Sunil Pancholi, Ricardo Ribas, André Nicolas, Didier Meseure, Anne Vincent-Salomon, Cécile Reyes, Audrey Rapinat, David Gentien, Thibaut Larcher, Mylène Bohec, Sylvain Baulande, Virginie Bernard, Didier Decaudin, Florence Coussy, Muriel Le Romancer, Guillaume Dutertre, Zakia Tariq, Paul Cottu, Keltouma Driouch, Ivan Bièche, Lesley-Ann Martin, Elisabetta Marangoni
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Identifying novel therapies for the treatment of CDK4/6 inhibitor-resistant patients is of great importance. Here, the authors demonstrate that PLK1 inhibition is a potential therapeutic target in CCND1-driven and in RB-positive Palbociclib-resistant
Externí odkaz:
https://doaj.org/article/cbbadef41cb14a1b91639138a1f60fcb
Autor:
Paula Azorin, Florian Bonin, Ahmad Moukachar, Aurélie Ponceau, Sophie Vacher, Ivan Bièche, Elisabetta Marangoni, Laetitia Fuhrmann, Anne Vincent-Salomon, Rosette Lidereau, Keltouma Driouch
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-15 (2018)
Abstract Background Kindlin-1, − 2, and − 3 are the three members of the Kindlin family. They are best known as regulators of integrin functions, contributing to fundamental biological processes such as cell survival, adhesion and migration. Thei
Externí odkaz:
https://doaj.org/article/d6601500e7e14b119d4343b4d2a0ea87
Autor:
Florian Bonin, Karim Taouis, Paula Azorin, Ambre Petitalot, Zakia Tariq, Sebastien Nola, Nadège Bouteille, Sandrine Tury, Sophie Vacher, Ivan Bièche, Khadija Ait Rais, Gaelle Pierron, Laetitia Fuhrmann, Anne Vincent-Salomon, Etienne Formstecher, Jacques Camonis, Rosette Lidereau, François Lallemand, Keltouma Driouch
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background The WW domain-containing oxidoreductase (WWOX) gene, frequently altered in breast cancer, encodes a tumor suppressor whose function is mediated through its interactions with cancer-related proteins, such as the pro-apoptotic prote
Externí odkaz:
https://doaj.org/article/3bfce873c073485588450a3f1f67b33f
Publikováno v:
Cells, Vol 10, Iss 5, p 1051 (2021)
The WW domain-containing oxidoreductase gene (WWOX) was cloned 21 years ago as a putative tumor suppressor gene mapping to chromosomal fragile site FRA16D. The localization of WWOX in a chromosomal region frequently altered in human cancers has initi
Externí odkaz:
https://doaj.org/article/e570052e2bfb47e1b8f04ee931ea0126
Autor:
Thibault Passeri, Tom Gutman, Abderaouf Hamza, Homa Adle-Biassette, Elodie Girard, Romane Beaurepere, Zakia Tariq, Odette Mariani, Ahmed Dahmani, Christine Bourneix, Rosaria Abbritti, Keltouma Driouch, Mylène Bohec, Nicolas Servant, Sylvain Baulande, Didier Decaudin, Jean-Pierre Guichard, Valentin Calugaru, Loïc Feuvret, Jean-Marc Guinebretière, Laurence Champion, Ivan Bièche, Sébastien Froelich, Hamid Mammar, Julien Masliah-Planchon
Publikováno v:
Journal of Neurosurgery. :1-11
OBJECTIVE Chordomas are rare bone neoplasms characterized by a high recurrence rate and no benefit from any approved medical treatment to date. However, the investigation of molecular alterations in chordomas could be essential to prognosticate, guid