Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kelsie Eichel"'
Autor:
Samantha I. Liang, Bettina van Lengerich, Kelsie Eichel, Minkwon Cha, David M. Patterson, Tae-Young Yoon, Mark von Zastrow, Natalia Jura, Zev J. Gartner
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2593-2600 (2018)
Summary: Growth factor binding to EGFR drives conformational changes that promote homodimerization and transphosphorylation, followed by adaptor recruitment, oligomerization, and signaling through Ras. Whether specific receptor conformations and olig
Externí odkaz:
https://doaj.org/article/280c94300e0942188e4040eef907c2e2
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22677 (2011)
Transcriptional control of gene regulation is an intricate process that requires precise orchestration of a number of molecular components. Studying its evolution can serve as a useful model for understanding how complex molecular machines evolve. On
Externí odkaz:
https://doaj.org/article/2d378b57c2b2491c86cfc87bb27bc0ff
Autor:
Nobuko Suzuki, Yan Zou, HaoSheng Sun, Kelsie Eichel, Meiyu Shao, Mushaine Shih, Kang Shen, Chieh Chang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(45)
Choreographic dendritic arborization takes place within a defined time frame, but the timing mechanism is currently not known. Here, we report that the precisely timed lin-4-lin-14 regulatory circuit triggers an initial dendritic growth activity, whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb4f53dfe1791a3955e7cac762fe566
https://pubmed.ncbi.nlm.nih.gov/36322763
https://pubmed.ncbi.nlm.nih.gov/36322763
Autor:
Kelsie Eichel, Kang Shen
Publikováno v:
Developmental biology. 489
Neurons are highly polarized cells with extensive axonal and dendritic projections that send and receive signals over long distances. Neuronal polarity requires sorting and maintaining a unique set of proteins to the neuron's distinct axonal and soma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9584652557aea15dcac1bdc647332ef4
https://pubmed.ncbi.nlm.nih.gov/35640681
https://pubmed.ncbi.nlm.nih.gov/35640681
Autor:
Kelsie Eichel, Takeshi Uenaka, Vivek Belapurkar, Rui Lu, Shouqiang Cheng, Joseph S. Pak, Caitlin A. Taylor, Thomas C. Südhof, Robert Malenka, Marius Wernig, Engin Özkan, David Perrais, Kang Shen
Publikováno v:
Nature. 609(7925)
Neurons are highly polarized cells that face the fundamental challenge of compartmentalizing a vast and diverse repertoire of proteins in order to function properly1. The axon initial segment (AIS) is a specialized domain that separates a neuron’s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64aa2c822017b762b5240c0cd53d1370
https://pubmed.ncbi.nlm.nih.gov/35978188
https://pubmed.ncbi.nlm.nih.gov/35978188
Autor:
Matthieu Masureel, Jean-Baptiste Sibarita, Damien Jullié, Ron O. Dror, Naomi R. Latorraca, Mark von Zastrow, Benjamin Barsi-Rhyne, Kelsie Eichel
Publikováno v:
Nature
β-arrestins are critical regulator and transducer proteins for G-protein-coupled receptors (GPCRs). β-arrestin is widely believed to be activated by forming a stable and stoichiometric GPCR-β-arrestin scaffold complex, which requires and is driven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2994063a32f220faa6c514d3fb7623aa
http://europepmc.org/articles/PMC6058965
http://europepmc.org/articles/PMC6058965
Autor:
Mark von Zastrow, Kelsie Eichel
Publikováno v:
Trends in pharmacological sciences, vol 39, iss 2
G protein-coupled receptors (GPCRs) comprise a large and diverse class of signal-transducing receptors that undergo dynamic and isoform-specific membrane trafficking. GPCRs thus have an inherent potential to initiate or regulate signaling reactions f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be4de9971eb8ba29d0bb8405773edb8
https://escholarship.org/uc/item/0f48v0nn
https://escholarship.org/uc/item/0f48v0nn
Autor:
Bettina van Lengerich, Mark von Zastrow, David M. Patterson, Minkwon Cha, Natalia Jura, Tae-Young Yoon, Kelsie Eichel, Zev J. Gartner, Samantha I. Liang
Publikováno v:
Cell reports
Cell Reports, Vol 22, Iss 10, Pp 2593-2600 (2018)
Cell reports, vol 22, iss 10
Cell Reports, Vol 22, Iss 10, Pp 2593-2600 (2018)
Cell reports, vol 22, iss 10
Summary Growth factor binding to EGFR drives conformational changes that promote homodimerization and transphosphorylation, followed by adaptor recruitment, oligomerization, and signaling through Ras. Whether specific receptor conformations and oligo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6c418dc894ba0f38c7542e55eb05e9
https://pubmed.ncbi.nlm.nih.gov/29514089
https://pubmed.ncbi.nlm.nih.gov/29514089
Autor:
Morgan, O'Hayre, Kelsie, Eichel, Silvia, Avino, Xuefeng, Zhao, Dana J, Steffen, Xiaodong, Feng, Kouki, Kawakami, Junken, Aoki, Karen, Messer, Roger, Sunahara, Asuka, Inoue, Mark, von Zastrow, J Silvio, Gutkind
Publikováno v:
Science signaling. 10(484)
The β2 adrenergic receptor (β2AR) has provided a paradigm to elucidate how G protein-coupled receptors (GPCRs) control intracellular signaling, including the discovery that β-arrestins, which bind to ligand-activated GPCRs, are central for GPCR fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66adcb7588ead04346a867a229144f3a
https://pubmed.ncbi.nlm.nih.gov/28634209
https://pubmed.ncbi.nlm.nih.gov/28634209
Publikováno v:
Nature cell biology
β-Arrestins critically regulate G-protein-coupled receptor (GPCR) signalling, not only 'arresting' the G protein signal but also modulating endocytosis and initiating a discrete G-protein-independent signal through MAP kinase. Despite enormous recen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5835c2a5a74e24f3df45e2d336f3436f
https://pubmed.ncbi.nlm.nih.gov/27046816
https://pubmed.ncbi.nlm.nih.gov/27046816