Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kelsi, Swope"'
Autor:
Kelsi Swope, Josh Morton, Gregory P. Pogue, Leigh Burden, Nicholas Partain, Steve Hume, John Shepherd, Carrie A. Simpson, Miles B. Brennan, Thomas C. Furman, Sheila Kingrey-Gebe, Theresa Martinez, Jim McDonough, Michael H. Pauly, Kevin J. Whaley, Larry Zeitlin, Barry Bratcher, Hugh Haydon
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
The ongoing SARS-CoV-2 coronavirus pandemic of 2020–2021 underscores the need for manufacturing platforms that can rapidly produce monoclonal antibody (mAb) therapies. As reported here, a platform based on Nicotiana benthamiana produced mAb therape
Externí odkaz:
https://doaj.org/article/0444f122130744d095e196c092b78bd8
Autor:
Jennifer K. DeMarco, Joshua M. Royal, William E. Severson, Jon D. Gabbard, Steve Hume, Josh Morton, Kelsi Swope, Carrie A. Simpson, John W. Shepherd, Barry Bratcher, Kenneth E. Palmer, Gregory P. Pogue
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1346 (2021)
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits
Externí odkaz:
https://doaj.org/article/d948abd924354895b2c5b1c46d082bd9
Autor:
Joshua M. Royal, Carrie A. Simpson, Alison A. McCormick, Amanda Phillips, Steve Hume, Josh Morton, John Shepherd, Youngjun Oh, Kelsi Swope, Jennifer L. DeBeauchamp, Richard J. Webby, Robert W. Cross, Viktoriya Borisevich, Thomas W. Geisbert, Jennifer K. Demarco, Barry Bratcher, Hugh Haydon, Gregory P. Pogue
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1347 (2021)
Stable, effective, easy-to-manufacture vaccines are critical to stopping the COVID-19 pandemic resulting from the coronavirus SARS-CoV-2. We constructed a vaccine candidate CoV-RBD121-NP, which is comprised of the SARS-CoV-2 receptor-binding domain (
Externí odkaz:
https://doaj.org/article/43b61c27594a4cee8b9a7611a625c5e8
Autor:
Andrea R. Thurman, Thomas R. Moench, Marshall Hoke, Joseph A. Politch, Howard Cabral, Emilie Mausser, Ellena Nador, Josh Morton, Krystal Hamorsky, Kelsi Swope, Barry Bratcher, Deborah J. Anderson, Kevin J. Whaley
Publikováno v:
American Journal of Obstetrics and Gynecology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a90972b82b758e750b545bf6beec626
https://doi.org/10.1016/j.ajog.2023.02.024
https://doi.org/10.1016/j.ajog.2023.02.024
Autor:
Kelsi, Swope, Josh, Morton, Gregory P, Pogue, Steve, Hume, Michael H, Pauly, John, Shepherd, Carrie A, Simpson, Barry, Bratcher, Kevin J, Whaley, Larry, Zeitlin, Keith R, Davis, Hugh, Haydon
Publikováno v:
Methods in enzymology. 660
Monoclonal antibodies (mAbs) hold great promise for treating diseases ranging from cancer to infectious disease. Manufacture of mAbs is challenging, expensive, and time-consuming using mammalian systems. We describe detailed methods used by Kentucky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2dd51b13b1765289cec7315a4129cef7
https://pubmed.ncbi.nlm.nih.gov/34742392
https://pubmed.ncbi.nlm.nih.gov/34742392
Autor:
Samuel K. Lai, Bhawana Shrestha, Thomas R. Moench, Massoud Motamedi, Henry Pham, Michael H. Pauly, Josh Morton, Gracie Vargas, Kevin J. Whaley, Larry Zeitlin, Carrie A. Simpson, Alison Schaefer, Kelsi Swope, Kathleen L. Vincent, Yong Zhu, Miles B. Brennan, Barry Bratcher
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Nearly half of all pregnancies in the United States are unintended due to millions of women avoiding available hormonal contraceptive methods as a result of real and/or perceived side effects associated with the use of exogenous hormones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e68710949be7983f8592853a85da6d
http://europepmc.org/articles/PMC8640842
http://europepmc.org/articles/PMC8640842
Autor:
Gregory P. Pogue, Steve Hume, Jennifer K. DeMarco, Josh Morton, John W. Shepherd, Jon D. Gabbard, Joshua M. Royal, Kelsi Swope, Barry Bratcher, Kenneth E. Palmer, William Severson, Carrie A. Simpson
Publikováno v:
Vaccines
Vaccines, Vol 9, Iss 1346, p 1346 (2021)
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1346, p 1346 (2021)
Volume 9
Issue 11
We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b329a7578b16d5aa6c0a5474182ec467
https://pubmed.ncbi.nlm.nih.gov/34835277
https://pubmed.ncbi.nlm.nih.gov/34835277
Autor:
Kevin J. Whaley, Barry Bratcher, Hugh Haydon, Carrie A. Simpson, Josh Morton, Keith R. Davis, Gregory P. Pogue, Michael H. Pauly, Steve Hume, Kelsi Swope, Larry Zeitlin, John W. Shepherd
Publikováno v:
Methods in Enzymology ISBN: 9780323907378
Monoclonal antibodies (mAbs) hold great promise for treating diseases ranging from cancer to infectious disease. Manufacture of mAbs is challenging, expensive, and time-consuming using mammalian systems. We describe detailed methods used by Kentucky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aecff14492cc9515dbb7d65a83a54b4
https://doi.org/10.1016/bs.mie.2021.05.011
https://doi.org/10.1016/bs.mie.2021.05.011
Autor:
Hugh Haydon, Amanda Phillips, Gregory P. Pogue, Robert W. Cross, Steve Hume, Joshua M. Royal, Jennifer DeBeauchamp, Thomas W. Geisbert, Josh Morton, Alison A. McCormick, John W. Shepherd, Carrie A. Simpson, Viktoriya Borisevich, Barry Bratcher, Jennifer K. DeMarco, Richard J. Webby, Kelsi Swope, Young Jun Oh
Publikováno v:
Vaccines, Vol 9, Iss 1347, p 1347 (2021)
Vaccines
Volume 9
Issue 11
Vaccines
Volume 9
Issue 11
Stable, effective, easy-to-manufacture vaccines are critical to stopping the COVID-19 pandemic resulting from the coronavirus SARS-CoV-2. We constructed a vaccine candidate CoV-RBD121-NP, which is comprised of the SARS-CoV-2 receptor-binding domain (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6906ad3b34797bf0600d09a380a93f8
https://doi.org/10.3390/vaccines9111347
https://doi.org/10.3390/vaccines9111347
Autor:
Lisa Fernando, James Pettitt, Judie B. Alimonti, Ernie Hiatt, Jonathan Audet, Alexander Bello, Ognian Bohorov, Josh Morton, Jenna Aviles, Kelsi Swope, Larry Zeitlin, Ashley K. Johnson, Kevin J. Whaley, Haiyan Wei, Hugues Fausther-Bovendo, Charles Goodman, Gary Wong, Gene G. Olinger, Natasha Bohorova, Jesus Velasco, Xiangguo Qiu, Michael H. Pauly, James E. Strong, Do Jin Kim, Bianli Xu, Gary P. Kobinger
Publikováno v:
Nature
Without an approved vaccine or treatments, Ebola outbreak management has been limited to palliative care and barrier methods to prevent transmission. These approaches, however, have yet to end the 2014 outbreak of Ebola after its prolonged presence i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afee8793645a36e7799f2ba0f9a57fd8
https://doi.org/10.1038/nature13777
https://doi.org/10.1038/nature13777