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Autor:
Mark E. Lustberg, Kelsey Van Deusen, Suresh de Silva, Li Wu, Jessica M. Mates, Robert A. Baiocchi, Jesse J. Kwiek
Publikováno v:
Retrovirology : research and treatment
Human immunodeficiency virus type 1 (HIV-1) latency is a major barrier to a cure of AIDS. Latently infected cells harbor an integrated HIV-1 genome but are not actively producing HIV-1. Histone deacetylase (HDAC) inhibitors, such as vorinostat (SAHA)