Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kelsey Rosbach"'
Autor:
Rebecca Richards-Kortum, Ann M. Gillenwater, Nitin Nitin, Michelle D. Williams, Kelsey Rosbach, Adel K. El-Naggar
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 6, Pp 542-551 (2009)
Background: The development of noninvasive molecular imaging approaches has the potential to improve management of cancer. Methods: In this study, we demonstrate the potential of noninvasive topical delivery of an epidermal growth factor-Alexa 647 (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcaabcf079c28df4a226dfca373daf2c
https://doi.org/10.1593/neo.09188
https://doi.org/10.1593/neo.09188
Autor:
Jessica Wu, Jennifer T. Nguyen, Rebecca Richards-Kortum, Kelsey Rosbach, Anne Hellebust, Ann M. Gillenwater, Nadarajah Vigneswaran
Publikováno v:
Journal of biomedical optics. 18(12)
In this longitudinal study, a mouse model of 4-nitroquinoline 1-oxide chemically induced tongue carcinogenesis was used to assess the ability of optical imaging with exogenous and endogenous contrast to detect neoplastic lesions in a heterogeneous mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da8247b1d452d055ae7523eded978df
https://pubmed.ncbi.nlm.nih.gov/24362926
https://pubmed.ncbi.nlm.nih.gov/24362926
Autor:
Wei Yang, Rebecca Richards-Kortum, Timothy J. Muldoon, Kelly K. Hunt, Lavinia P. Middleton, Kelsey Rosbach, Mohammad Quraishi, Dongsuk Shin, Tse Kuan Yu, Funda Meric-Bernstam
Publikováno v:
Biomedical Optics Express
This prospective pilot study evaluates the potential of high-resolution fiber optic microscopy (HRFM) to identify lymph node metastases in breast cancer patients. 43 lymph nodes were collected from 14 consenting breast cancer patients. Proflavine dye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a3f946b9f6bc78edb37f8f98785b7a
https://pubmed.ncbi.nlm.nih.gov/21258518
https://pubmed.ncbi.nlm.nih.gov/21258518
Autor:
Sharmila Anandasabapathy, Mark C. Pierce, Peter K Thompson, Kelsey Rosbach, Rebecca Richards-Kortum, Nadhi Thekkek, Ann M. Gillenwater, Raymond Kaufman
Publikováno v:
Biomedical Optics and 3-D Imaging.
We have developed a high-resolution fluorescence microendoscope capable of imaging sub-cellular morphology in vivo, in real-time. We report our latest results in clinical studies for early cancer detection in the cervix, oral cavity, and esophagus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a2f699832511724f9634286a4102d50
https://doi.org/10.1364/biomed.2010.btud93
https://doi.org/10.1364/biomed.2010.btud93
Publikováno v:
Biomedical Optics and 3-D Imaging.
Three probes targeting molecular or morphologic characteristics of cancer were topically applied to freshly resected oral tissue. Optical contrast was used to predict the region of neoplasia; predicted regions agree well with histopathology maps.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca655012e1ccd6d3d2f190d1b0642a79
https://doi.org/10.1364/biomed.2010.bwd2
https://doi.org/10.1364/biomed.2010.bwd2
Publikováno v:
Cancer Research. 75:1303-1303
Cytotoxicity assays play a central role in studying the function of immune effector cells such as cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Traditionally, cytotoxicity assays have been performed using 51Chromium (51Cr) and Calcein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::472b20b1c7a828a0dc865aafaa5e65d5
https://doi.org/10.1158/1538-7445.am2015-1303
https://doi.org/10.1158/1538-7445.am2015-1303
Publikováno v:
The Journal of Immunology. 194:69.24-69.24
Cytotoxicity assays play a central role in studying the function of immune effector cells such as cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Traditionally, cytotoxicity assays have been performed using 51Chromium (51Cr) and Calcein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61402cdcc69ac75828cba5852b27ec64
https://doi.org/10.4049/jimmunol.194.supp.69.24
https://doi.org/10.4049/jimmunol.194.supp.69.24
Autor:
Kelsey Rosbach, Jessica Wu, Nadarajah Vigneswaran, Richard A. Schwarz, Anne Hellebust, Ann M. Gillenwater, Rebecca Richards-Kortum, Jennifer T. Nguyen
Publikováno v:
Cancer Research. 71:3265-3265
The purpose of this study was to evaluate multispectral imaging of autofluorescence and targeted fluorescent contrast agents for non-invasive diagnosis of epithelial dysplasia and cancer using a mouse model of oral tongue carcinogenesis. In humans, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebb2901676dc7f499678dd3b1cb04ec9
https://doi.org/10.1158/1538-7445.am2011-3265
https://doi.org/10.1158/1538-7445.am2011-3265
Autor:
Kelsey Rosbach, Timothy J. Muldoon, Rebecca Richards-Kortum, Michelle A. Williams, Ann M. Gillenwater
Publikováno v:
Molecular Cancer Therapeutics. 8:A223-A223
Background: Early detection of dysplasia and cancer in the oral cavity dramatically improves patient survival, however, early stage disease can be difficult to identify with a conventional oral examination. Non-invasive, molecular-specific optical im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d413b859b4d4103f713daa1451149b04
https://doi.org/10.1158/1535-7163.targ-09-a223
https://doi.org/10.1158/1535-7163.targ-09-a223
Publikováno v:
Translational Oncology. (3):160-171
Biomarkers of cancer can indicate the presence of disease and serve as therapeutic targets. Our goal is to develop an optical imaging approach using molecularly targeted contrast agents to assess several centimeters of mucosal surface for mapping exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f527c467b67d403dedcd59d86e123f9b