Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kelsey R. Bounds"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 11 (2017)
BackgroundCardiac fibrosis occurs because of disruption of the extracellular matrix network leading to myocardial dysfunction. Angiotensin II has been implicated in the development of cardiac fibrosis. Recently, microRNAs have been identified as an a
Externí odkaz:
https://doaj.org/article/c2422c1f198f46a4847b96cfdaad9236
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
Our understanding of how microRNAs (miRNAs) regulate gene networks and affect different molecular pathways leading to various human pathologies has significantly improved over the years. In contrary, the role of miRNAs in pregnancy-related hypertensi
Externí odkaz:
https://doaj.org/article/8506d1a6c3a346ecadd5bdefc2b7a2d2
Autor:
Kempapura Murthy, Sarah Spencer, Holly C Groom, Sara S Kim, Laura J. Edwards, Zuha Jeddy, Lauren Beacham, F. Liaini Gross, Fatimah S. Dawood, Edward A. Belongia, Shivaprakash Gangappa, Allison L. Naleway, Meredith G Wesley, Min Z. Levine, Sarah Ball, Margarita Mishina, Mark G. Thompson, Suryaprakash Sambhara, Danielle R. Hunt, Weiping Cao, Alicia M. Fry, Manjusha Gaglani, Brendan Flannery, Kelsey R. Bounds
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background RIV4 and cell-culture based inactivated influenza vaccine (ccIIV4) have not been compared to egg-based IIV4 in healthcare personnel, a population with frequent influenza vaccination that may blunt vaccine immune responses over time. We con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be34605dd41fc9ec923c0c5cba7e0938
https://doi.org/10.1093/cid/ciab566
https://doi.org/10.1093/cid/ciab566
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 2 (2015)
The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE). We propose 4 pathways that involve excessive innate immunity that lead to most forms of PE.
Externí odkaz:
https://doaj.org/article/87b13e02a78d4023b66da1ff14365a59
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Inflammation mediated by both innate and adaptive immune cells is necessary for several important processes during pregnancy. Pro-inflammatory immune cell activation plays a critical role in embryo implantation, placentation, and parturition; however
Externí odkaz:
https://doaj.org/article/6a9da486584a4ca9a9c4654fe3dbf21d
Autor:
Brett M. Mitchell, Shelley Kopriva, Kelsey R. Bounds, M. Karen Newell-Rogers, Piyali Chatterjee, Valorie L. Chiasson
Publikováno v:
Pregnancy Hypertension. 13:154-160
Objective Innate immune system activation and excessive inflammation contributes to hypertension during pregnancy (HTN-preg). Activation of Toll-like receptors (TLRs), the primary innate immune system sensor, is evident in women with HTN-preg and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27ac9ad12782e646699d40ed8c94efb
https://doi.org/10.1016/j.preghy.2018.06.011
https://doi.org/10.1016/j.preghy.2018.06.011
Autor:
Lochana Manandhar, Bilal Aziz, Brett M. Mitchell, Marcos Hernandez, Piyali Chatterjee, Valorie L. Chiasson, Kelsey R. Bounds, Abhinandan R. Pakanati
Publikováno v:
Hypertension. 71:199-207
The calcineurin inhibitor cyclosporine A suppresses the immune system but promotes hypertension, vascular dysfunction, and renal damage. Cyclosporine A decreases regulatory T cells and this contributes to the development of hypertension. However, cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c124ad7623ea841f6c83111a12818859
https://doi.org/10.1161/hypertensionaha.117.10306
https://doi.org/10.1161/hypertensionaha.117.10306
Autor:
Abhinandan R. Pakanati, Kelsey R. Bounds, Marcos Hernandez, Valorie L. Chiasson, Kristina J. Young, Brett M. Mitchell
Publikováno v:
Hypertension. 70:183-191
The immunosuppressive calcineurin inhibitors cyclosporine A and tacrolimus alter T-cell subsets and can cause hypertension, vascular dysfunction, and renal toxicity. We and others have reported that cyclosporine A and tacrolimus decrease anti-inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5603b857d5166653c87e00e23b94a7
https://doi.org/10.1161/hypertensionaha.117.09374
https://doi.org/10.1161/hypertensionaha.117.09374
Autor:
Brett M. Mitchell, Valorie L. Chiasson, Piyali Chatterjee, Ayelet Chajut, Lena Pinzur, Liat Flaishon, Racheli Ofir, Eytan Abraham, Kathleen A. Jones, Shani Raveh, Kelsey R. Bounds
Publikováno v:
Clinical Science. 130:513-523
Pre-eclampsia, the development of hypertension and proteinuria or end-organ damage during pregnancy, is a leading cause of both maternal and fetal morbidity and mortality, and there are no effective clinical treatments for pre-eclampsia aside from de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3186ef12ff5a765b5f4ad2102e6ef56
https://doi.org/10.1042/cs20150555
https://doi.org/10.1042/cs20150555
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cardiac fibrosis occurs because of disruption of the extracellular matrix network leading to myocardial dysfunction. Angiotensin II has been implicated in the development of cardiac fibrosis. Recently, micro RNA s have been identified as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d463786cd100a56d953f548c9bce148
https://doi.org/10.1161/jaha.117.006763
https://doi.org/10.1161/jaha.117.006763