Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kelsey R, Beavers"'
Autor:
Tianwei Shen, Jeremy W. Mares, Kasey C. Vickers, Sharon M. Weiss, Taylor E. Kavanaugh, Thomas A. Werfel, Kameron V. Kilchrist, Carrie B. Wiese, Craig L. Duvall, Joshua S. Fain, Kelsey R. Beavers
Publikováno v:
Advanced Materials. 28:7984-7992
Self-assembled polymer/porous silicon nanocomposites overcome intracellular and systemic barriers for in vivo application of peptide nucleic acid (PNA) anti-microRNA therapeutics. Porous silicon (PSi) is leveraged as a biodegradable scaffold with hig
Publikováno v:
Advanced Drug Delivery Reviews. 88:123-137
MicroRNA (miRNA) are noncoding RNA that provide an endogenous negative feedback mechanism for translation of messenger RNA (mRNA) into protein. Single miRNAs can regulate hundreds of mRNAs, enabling miRNAs to orchestrate robust biological responses b
Publikováno v:
ACS Applied Materials & Interfaces. 6:13510-13519
This work examines the influence of charge density and surface passivation on the DNA-induced corrosion of porous silicon (PSi) waveguides in order to improve PSi biosensor sensitivity, reliability, and reproducibility when exposed to negatively char
Autor:
Samantha M. Sarett, Craig L. Duvall, Kelsey R. Beavers, Christopher E. Nelson, Martina Miteva
Publikováno v:
Nanomedicine. 8:329-332
Publikováno v:
Analytical Chemistry. 85:1440-1446
This article presents a critical evaluation of silver nanorod arrays as substrates for assaying nucleic acid hybridization by surface enhanced Raman scattering (SERS). SERS spectra acquired on complementary oligos, alone or in combination, contain th
Publikováno v:
Chemistry of Materials. 22:2184-2189
Silver nanorod arrays fabricated by glancing angle deposition have found application as substrates for surface enhanced Raman scattering. A critical issue in the continued development of these substrates is their stability over time. The thermal stab
Publikováno v:
Nanotechnology. 26(27)
A versatile and scalable method for fabricating shape-engineered nano- and micrometer scale particles from mesoporous silicon (PSi) thin films is presented. This approach, based on the direct imprinting of porous substrates (DIPS) technique, facilita
Autor:
Jeremy W. Mares, Craig L. Duvall, Yiliang Zhao, Kelsey R. Beavers, Caleb M. Swartz, Sharon M. Weiss
Publikováno v:
Bioconjugate Chemistry
Peptide nucleic acids (PNA) are a unique class of synthetic molecules that have a peptide backbone and can hybridize with nucleic acids. Here, a versatile method has been developed for the automated, in situ synthesis of PNA from a porous silicon (PS
Autor:
Kelsey R. Beavers, Amy T. Shah, Craig L. Duvall, Wesley W. Sit, Melissa C. Skala, Jason M. Tucker-Schwartz
Publikováno v:
Biomedical optics express. 5(6)
Current imaging techniques capable of tracking nanoparticles in vivo supply either a large field of view or cellular resolution, but not both. Here, we demonstrate a multimodality imaging platform of optical coherence tomography (OCT) techniques for
Autor:
Brian C, Evans, Christopher E, Nelson, Shann S, Yu, Kelsey R, Beavers, Arnold J, Kim, Hongmei, Li, Heather M, Nelson, Todd D, Giorgio, Craig L, Duvall
Publikováno v:
Journal of visualized experiments : JoVE. (73)
Phospholipid bilayers that constitute endo-lysosomal vesicles can pose a barrier to delivery of biologic drugs to intracellular targets. To overcome this barrier, a number of synthetic drug carriers have been engineered to actively disrupt the endoso