Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kelsey N. Boschert"'
Autor:
Andrew D. Huber, Jennifer J. Wolf, Dandan Liu, Anna T. Gres, Jing Tang, Kelsey N. Boschert, Maritza N. Puray-Chavez, Dallas L. Pineda, Thomas G. Laughlin, Emily M. Coonrod, Qiongying Yang, Juan Ji, Karen A. Kirby, Zhengqiang Wang, Stefan G. Sarafianos
Publikováno v:
mSphere, Vol 3, Iss 2 (2018)
ABSTRACT Heteroaryldihydropyrimidines (HAPs) are compounds that inhibit hepatitis B virus (HBV) replication by modulating viral capsid assembly. While their biophysical effects on capsid assembly in vitro have been previously studied, the effect of H
Externí odkaz:
https://doaj.org/article/d21fb67e4b2b429c9a5549748928bef6
Autor:
Jayakanth Kankanala, Jennifer J. Wolf, Zhengqiang Wang, Andrew D. Huber, Stefan G. Sarafianos, Jing Tang, Jiashu Xie, Kelsey N. Boschert, Dallas L. Pineda
Publikováno v:
European journal of medicinal chemistry. 164
Chronic hepatitis B virus (HBV) infection represents a major health threat. Current FDA-approved drugs do not cure HBV. Targeting HBV core protein (Cp) provides an attractive approach toward HBV inhibition and possibly infection cure. We have previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba43d923885c71c91f2e32bf47d1c338
https://pubmed.ncbi.nlm.nih.gov/30594676
https://pubmed.ncbi.nlm.nih.gov/30594676
Autor:
Maxwell D. Leslie, Michael A. Parniak, Kelsey N. Boschert, Maritza Puray-Chavez, Karen A. Kirby, Zhengqiang Wang, Andrew D. Huber, Jing Tang, Kamalendra Singh, Hiroaki Mitsuya, Maria Boftsi, Megan A. Sheridan, Stefan G. Sarafianos, Eleftherios Michailidis, Jennifer J. Wolf
Publikováno v:
Antimicrobial Agents and Chemotherapy. 61
Hepatitis B virus (HBV) RNase H (RNH) is an appealing therapeutic target due to its essential role in viral replication. RNH inhibitors (RNHIs) could help to more effectively control HBV infections. Here, we report 3-hydroxypyrimidine-2,4-diones as n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4107b0ed22f3add7ca93a638eedafd3
https://doi.org/10.1128/aac.00245-17
https://doi.org/10.1128/aac.00245-17