Výsledky vyhledávání - "Kelsey M Vollmer"

Akademický článek

An opioid-gated thalamoaccumbal circuit for the suppression of reward seeking in mice

Autor: Kelsey M. Vollmer, Lisa M. Green, Roger I. Grant, Kion T. Winston, Elizabeth M. Doncheck, Christopher W. Bowen, Jacqueline E. Paniccia, Rachel E. Clarke, Annika Tiller, Preston N. Siegler, Bogdan Bordieanu, Benjamin M. Siemsen, Adam R. Denton, Annaka M. Westphal, Thomas C. Jhou, Jennifer A. Rinker, Jacqueline F. McGinty, Michael D. Scofield, James M. Otis

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

Abstract Suppression of dangerous or inappropriate reward-motivated behaviors is critical for survival, whereas therapeutic or recreational opioid use can unleash detrimental behavioral actions and addiction. Nevertheless, the neuronal systems that s

Externí odkaz: https://doaj.org/article/f0bc29247a204771859cdb2512d2b3cb

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Akademický článek

A Subset of Nucleus Accumbens Neurons Receiving Dense and Functional Prelimbic Cortical Input Are Required for Cocaine Seeking

Autor: Benjamin M. Siemsen, Sarah M. Barry, Kelsey M. Vollmer, Lisa M. Green, Ashley G. Brock, Annaka M. Westphal, Raven A. King, Derek M. DeVries, James M. Otis, Christopher W. Cowan, Michael D. Scofield

Publikováno v: Frontiers in Cellular Neuroscience, Vol 16 (2022)

BackgroundPrelimbic cortical projections to the nucleus accumbens core are critical for cue-induced cocaine seeking, but the identity of the accumbens neuron(s) targeted by this projection, and the transient neuroadaptations contributing to relapse w

Externí odkaz: https://doaj.org/article/b5fc6239108848da9c09372d755b51fc

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Akademický článek

A Novel Assay Allowing Drug Self-Administration, Extinction, and Reinstatement Testing in Head-Restrained Mice

Autor: Kelsey M. Vollmer, Elizabeth M. Doncheck, Roger I. Grant, Kion T. Winston, Elizaveta V. Romanova, Christopher W. Bowen, Preston N. Siegler, Lisa M. Green, Ana-Clara Bobadilla, Ivan Trujillo-Pisanty, Peter W. Kalivas, James M. Otis

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 15 (2021)

Multiphoton microscopy is one of several new technologies providing unprecedented insight into the activity dynamics and function of neural circuits. Unfortunately, some of these technologies require experimentation in head-restrained animals, limiti

Externí odkaz: https://doaj.org/article/e849e26865d34ed0bb63394d673d8812

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Akademický článek

Specialized coding patterns among dorsomedial prefrontal neuronal ensembles predict conditioned reward seeking

Autor: Roger I Grant, Elizabeth M Doncheck, Kelsey M Vollmer, Kion T Winston, Elizaveta V Romanova, Preston N Siegler, Heather Holman, Christopher W Bowen, James M Otis

Publikováno v: eLife, Vol 10 (2021)

Non-overlapping cell populations within dorsomedial prefrontal cortex (dmPFC), defined by gene expression or projection target, control dissociable aspects of reward seeking through unique activity patterns. However, even within these defined cell po

Externí odkaz: https://doaj.org/article/ccc94d2bcad448289269753f9ea3d1a1

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