Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kelsey L. Tinkum"'
Autor:
Najla Kfoury, Tao Sun, Kwanha Yu, Nathan Rockwell, Kelsey L. Tinkum, Zongtai Qi, Nicole M. Warrington, Peter McDonald, Anuradha Roy, Scott J. Weir, Carrie A. Mohila, Benjamin Deneen, Joshua B. Rubin
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract Mechanisms underlying sex differences in cancer incidence are not defined but likely involve dimorphism (s) in tumor suppressor function at the cellular and organismal levels. As an example, sexual dimorphism in retinoblastoma protein (Rb) a
Externí odkaz:
https://doaj.org/article/be8f708cece04a41bfd595a9a82149a8
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment
Autor:
Jasmin Sponagel, Jill K. Jones, Cheryl Frankfater, Shanshan Zhang, Olivia Tung, Kevin Cho, Kelsey L. Tinkum, Hannah Gass, Elena Nunez, Douglas R. Spitz, Prakash Chinnaiyan, Jacob Schaefer, Gary J. Patti, Maya S. Graham, Audrey Mauguen, Milan Grkovski, Mark P. Dunphy, Simone Krebs, Jingqin Luo, Joshua B. Rubin, Joseph E. Ippolito
Publikováno v:
Med (New York, N.Y.). 3(11)
Brain cancer incidence and mortality rates are greater in males. Understanding the molecular mechanisms that underlie those sex differences could improve treatment strategies. Although sex differences in normal metabolism are well described, it is cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b5091f1bfa6befd26701c9c0f99f69
https://pubmed.ncbi.nlm.nih.gov/36108629
https://pubmed.ncbi.nlm.nih.gov/36108629
Autor:
Benjamin Deneen, Kelsey L. Tinkum, Joshua B. Rubin, Kwanha Yu, Peter R. McDonald, Anuradha Roy, Tao Sun, Zongtai Qi, Scott Weir, Nicole M. Warrington, Najla Kfoury, Carrie A. Mohila, Nathan Rockwell
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-13 (2018)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Mechanisms underlying sex differences in cancer incidence are not defined but likely involve dimorphism (s) in tumor suppressor function at the cellular and organismal levels. As an example, sexual dimorphism in retinoblastoma protein (Rb) activity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf618e92a31a4539114128c08077f14
http://link.springer.com/article/10.1186/s40478-018-0513-5
http://link.springer.com/article/10.1186/s40478-018-0513-5
Autor:
Scott Weir, Carrie A. Mohila, Kelsey L. Tinkum, Kwanha Yu, Benjamin Deneen, Peter R. McDonald, Anu Roy, Tao Sun, Nathan Rockwell, Najla Kfoury, Joshua B. Rubin
Publikováno v:
Neuro-Oncology. 19:vi38-vi38
Sex differences in cancer incidence are pervasive regardless of age or race. However, the molecular mechanisms underlying these differences remain undefined. Previously, we showed that sex differences in the regulation of retinoblastoma protein (Rb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f62bb843358e4b8881067a0816d07a4
https://doi.org/10.1093/neuonc/nox168.149
https://doi.org/10.1093/neuonc/nox168.149
Autor:
Helen Piwnica-Worms, David Piwnica-Worms, Erik D. Herzog, Lynn S. White, Luciano Marpegan, Kelsey L. Tinkum
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Reporter mice that enable the activity of the endogenous p21 promoter to be dynamically monitored in real time in vivo and under a variety of experimental conditions revealed ubiquitous p21 expression in mouse organs including the brain. Low light bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eebee5b959e04a832e0b101006cacf0
https://pubmed.ncbi.nlm.nih.gov/23918930
https://pubmed.ncbi.nlm.nih.gov/23918930
Autor:
Lynn S. White, Kelsey L. Tinkum, Helen Piwnica-Worms, Luciano Marpegan, Jinwu Sun, David Piwnica-Worms, Erik D. Herzog
Publikováno v:
Molecular and cellular biology. 31(18)
To interrogate endogenous p21(WAF1/CIP1) (p21) promoter activity under basal conditions and in response to various forms of stress, knock-in imaging reporter mice in which expression of firefly luciferase (FLuc) was placed under the control of the en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc51630f4acc1bfded320d085bcba25f
https://pubmed.ncbi.nlm.nih.gov/21791610
https://pubmed.ncbi.nlm.nih.gov/21791610
Autor:
Yunyuan V. Wang, Jian-Hua Mao, Helen Piwnica-Worms, Mathias Leblanc, Kurt A. Krummel, Allan Balmain, Kelsey L. Tinkum, Norma E. Fox, Geoffrey M. Wahl, David Piwnica-Worms, Dannielle D. Engle, Kenneth Kaushansky
Publikováno v:
Genesdevelopment. 25(13)
Cell cycle regulation in hematopoietic stem cells (HSCs) is tightly controlled during homeostasis and in response to extrinsic stress. p53, a well-known tumor suppressor and transducer of diverse stress signals, has been implicated in maintaining HSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadc246c6129dfed902cdc1722a107f9
https://pubmed.ncbi.nlm.nih.gov/21724834
https://pubmed.ncbi.nlm.nih.gov/21724834
Autor:
Thaddeus S. Stappenbeck, Catherine Kuzmicki, Kristina Marie Stemler, Andrew J. Loza, Helen Piwnica-Worms, Sabrina Jeter-Jones, Kelsey L. Tinkum, David Piwnica-Worms, Lynn S. White, Basia M. Michalski, Robert Pless
Publikováno v:
Cancer Research. 75:2316-2316
Short-term fasting in mice has been shown to increase survival from lethal doses of chemotherapy; however, the route of protection in these animals is unknown. In this study we demonstrate that fasting prior to chemotherapy protects small intestinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cee4e8af6f00e04591db49c11d2801a
https://doi.org/10.1158/1538-7445.am2015-2316
https://doi.org/10.1158/1538-7445.am2015-2316
Publikováno v:
The American journal of pathology. 169(4)
Exposure to ultraviolet (UV) irradiation is the major cause of nonmelanoma skin cancer, the most common form of cancer in the United States. UV irradiation has a variety of effects on the skin associated with carcinogenesis, including DNA damage and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122618b88ed05eb6fc905e066713e8ac
https://pubmed.ncbi.nlm.nih.gov/17003495
https://pubmed.ncbi.nlm.nih.gov/17003495