Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kelsey L. Lynch"'
Autor:
Elizabeth X. Kwan, Gina M. Alvino, Kelsey L. Lynch, Paula F. Levan, Haley M. Amemiya, Xiaobin S. Wang, Sarah A. Johnson, Joseph C. Sanchez, Madison A. Miller, Mackenzie Croy, Seung-been Lee, Maria Naushab, Antonio Bedalov, Josh T. Cuperus, Bonita J. Brewer, Christine Queitsch, M.K. Raghuraman
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112161- (2023)
Summary: Timely completion of genome replication is a prerequisite for mitosis, genome integrity, and cell survival. A challenge to this timely completion comes from the need to replicate the hundreds of untranscribed copies of rDNA that organisms ma
Externí odkaz:
https://doaj.org/article/52aee668d64145149ab27041aab50554
Publikováno v:
PLoS Genetics, Vol 15, Iss 10, p e1008430 (2019)
Chromosome replication in Saccharomyces cerevisiae is initiated from ~300 origins that are regulated by DNA sequence and by the limited abundance of six trans-acting initiation proteins (Sld2, Sld3, Dpb11, Dbf4, Sld7 and Cdc45). We set out to determi
Externí odkaz:
https://doaj.org/article/15671315f5cb4c279832ff5d239e0ecb
Autor:
Maria Naushab, M. K. Raghuraman, Madison Miller, Seung-been Lee, Kelsey L. Lynch, Josh T. Cuperus, Xiaobin S. Wang, Joseph C. Sanchez, Bonita J. Brewer, Haley M. Amemiya, Paula F. Levan, Christine Queitsch, Mackenzie Croy, Elizabeth X. Kwan, Gina M. Alvino, Sarah A. Johnson
Eukaryotes maintain hundreds of copies of ribosomal DNA (rDNA), many more than required for ribosome biogenesis, suggesting a yet undefined role for large rDNA arrays outside of ribosomal RNA synthesis. We demonstrate that reducing the Saccharomyces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fd1fbef8a791125112761bb2c68fd00
https://doi.org/10.1101/2021.02.25.432950
https://doi.org/10.1101/2021.02.25.432950
Autor:
Mongoljin Bat-Erdene, Melanie R. Dillon, Kelsey L. Lynch, Hannah C. Lewis, Daphne C. Avgousti
Virus infection necessarily requires redirecting cellular resources towards viral progeny production. Adenovirus encodes the histone-like protein VII that causes catastrophic global reorganization of host chromatin to promote virus infection. Protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::390ed1200c1b5160bb8f01d740e9a5a5
https://doi.org/10.1101/2020.12.11.418129
https://doi.org/10.1101/2020.12.11.418129
Autor:
Mongoljin Bat-Erdene, Kelsey L. Lynch, Daphne C. Avgousti, Robin J. Kaai, Hannah C. Lewis, Melanie R. Dillon, Edward A. Arnold
Publikováno v:
Curr Biol
Virus infection necessarily requires redirecting cellular resources toward viral progeny production. Adenovirus encodes the histone-like protein VII, which causes catastrophic global reorganization of host chromatin to promote virus infection. Protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d90f292a3c2d067c7d6bc8a02d9722
https://doi.org/10.1016/j.cub.2021.09.050
https://doi.org/10.1016/j.cub.2021.09.050
Autor:
David A. Ornelles, Kelsey L. Lynch, Daphne C. Avgousti, Linda R. Gooding, Charlie Garnett-Benson
Publikováno v:
FEBS letters. 593(24)
The DNA genome of eukaryotic cells is compacted by histone proteins within the nucleus to form chromatin. Nuclear-replicating viruses such as adenovirus have evolved mechanisms of chromatin manipulation to promote infection and subvert host defenses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91125b90c8323ee49451739a9792a47
https://pubmed.ncbi.nlm.nih.gov/31769503
https://pubmed.ncbi.nlm.nih.gov/31769503
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 15, Iss 10, p e1008430 (2019)
PLoS Genetics, Vol 15, Iss 10, p e1008430 (2019)
Chromosome replication in Saccharomyces cerevisiae is initiated from ~300 origins that are regulated by DNA sequence and by the limited abundance of six trans-acting initiation proteins (Sld2, Sld3, Dpb11, Dbf4, Sld7 and Cdc45). We set out to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cb3903efa6fc4e359b932be0542a3b
http://europepmc.org/articles/PMC6795477
http://europepmc.org/articles/PMC6795477
Chromosome replication inSaccharomyces cerevisiaeis initiated from roughly 300 origins that are regulated both by DNA sequence and by the limited abundance of fourtrans-actinginitiation proteins (Sld2, Sld3, Dpb11 and Dbf4, collectively called “SSD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbcb0efe8ee3b9b5d556c0b7f2dd6687
Autor:
Kelsey L. Lynch, Michael Freitag, Caitlin V. Mueller, Steven Friedman, Takahiko Sasaki, Zachary A. Lewis
Publikováno v:
Eukaryotic Cell. 13:990-1000
In response to genotoxic stress, ATR and ATM kinases phosphorylate H2A in fungi and H2AX in animals on a C-terminal serine. The resulting modified histone, called γH2A, recruits chromatin-binding proteins that stabilize stalled replication forks or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311de316d93bd42c54058143ebcd363c
https://doi.org/10.1128/ec.00117-14
https://doi.org/10.1128/ec.00117-14