Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kelsey Breslin"'
Autor:
Andres Tapia del Fierro, Bianca den Hamer, Natalia Benetti, Natasha Jansz, Kelan Chen, Tamara Beck, Hannah Vanyai, Alexandra D. Gurzau, Lucia Daxinger, Shifeng Xue, Thanh Thao Nguyen Ly, Iromi Wanigasuriya, Megan Iminitoff, Kelsey Breslin, Harald Oey, Yvonne D. Krom, Dinja van der Hoorn, Linde F. Bouwman, Timothy M. Johanson, Matthew E. Ritchie, Quentin A. Gouil, Bruno Reversade, Fabrice Prin, Timothy Mohun, Silvère M. van der Maarel, Edwina McGlinn, James M. Murphy, Andrew Keniry, Jessica C. de Greef, Marnie E. Blewitt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract The interplay between 3D chromatin architecture and gene silencing is incompletely understood. Here, we report a novel point mutation in the non-canonical SMC protein SMCHD1 that enhances its silencing capacity at endogenous developmental ta
Externí odkaz:
https://doaj.org/article/4b268abe87144921872eecf80d018c13
Autor:
Iromi Wanigasuriya, Sarah A. Kinkel, Tamara Beck, Ellise A. Roper, Kelsey Breslin, Heather J. Lee, Andrew Keniry, Matthew E. Ritchie, Marnie E. Blewitt, Quentin Gouil
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-11 (2022)
Abstract Embryonic development is dependent on the maternal supply of proteins through the oocyte, including factors setting up the adequate epigenetic patterning of the zygotic genome. We previously reported that one such factor is the epigenetic re
Externí odkaz:
https://doaj.org/article/e4430fcb138444b3b279b1aab8b8b2b5
Autor:
Natalia Benetti, Quentin Gouil, Andres Tapia del Fierro, Tamara Beck, Kelsey Breslin, Andrew Keniry, Edwina McGlinn, Marnie E. Blewitt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Parents transmit both genetic and epigenetic information to their offspring, with maternal effect genes being critical regulators of the offspring epigenome. Here they show that maternally deposited SMCHD1 has long-lasting effects on Hox gene express
Externí odkaz:
https://doaj.org/article/f3dd1a6eccaf4f698759ff576571bf98
Autor:
Iromi Wanigasuriya, Quentin Gouil, Sarah A Kinkel, Andrés Tapia del Fierro, Tamara Beck, Ellise A Roper, Kelsey Breslin, Jessica Stringer, Karla Hutt, Heather J Lee, Andrew Keniry, Matthew E Ritchie, Marnie E Blewitt
Publikováno v:
eLife, Vol 9 (2020)
Genomic imprinting establishes parental allele-biased expression of a suite of mammalian genes based on parent-of-origin specific epigenetic marks. These marks are under the control of maternal effect proteins supplied in the oocyte. Here we report e
Externí odkaz:
https://doaj.org/article/e994c277b0c146169eb4f3f1fb17b649
Autor:
Bhupinder Pal, Toula Bouras, Wei Shi, François Vaillant, Julie M. Sheridan, Naiyang Fu, Kelsey Breslin, Kun Jiang, Matthew E. Ritchie, Matthew Young, Geoffrey J. Lindeman, Gordon K. Smyth, Jane E. Visvader
Publikováno v:
Cell Reports, Vol 3, Iss 2, Pp 411-426 (2013)
The mammary epithelium is a dynamic, highly hormone-responsive tissue. To explore chromatin modifications underlying its lineage specification and hormone responsiveness, we determined genome-wide histone methylation profiles of mammary epithelial su
Externí odkaz:
https://doaj.org/article/a9d58ea584384454b49ee4fbf86fdd9a
Autor:
Quentin Gouil, Marnie E. Blewitt, Heather J. Lee, Sarah Kinkel, Andrew Keniry, Kelsey Breslin, Iromi Wanigasuriya, Matthew E. Ritchie, Ellise A Roper, Tamara Beck
Embryonic development is dependent on the maternal supply of proteins through the oocyte, including factors setting up the adequate epigenetic patterning of the zygotic genome. We previously reported that one such factor is the epigenetic repressor S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b430800fa047ffc8dfaf382cafba37d6
https://doi.org/10.1101/2021.10.21.465360
https://doi.org/10.1101/2021.10.21.465360
Autor:
Natalia Benetti, Quentin Gouil, Andres Tapia del Fierro, Tamara Beck, Kelsey Breslin, Andrew Keniry, Edwina McGlinn, Marnie E. Blewitt
Publikováno v:
Nature communications. 13(1)
Parents transmit genetic and epigenetic information to their offspring. Maternal effect genes regulate the offspring epigenome to ensure normal development. Here we report that the epigenetic regulator SMCHD1 has a maternal effect on Hox gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8be248cddc8d50b191983e54471ad2
https://pubmed.ncbi.nlm.nih.gov/35879318
https://pubmed.ncbi.nlm.nih.gov/35879318
Autor:
Kelsey Breslin, Natalia Benetti, Quentin Gouil, Marnie E. Blewitt, Edwina McGlinn, Tamara Beck, Andrew Keniry, Andrés Tapia del Fierro
Parents transmit genetic and epigenetic information to their offspring. Maternal effect genes regulate the offspring epigenome to ensure normal development. Here we report that the epigenetic regulator SMCHD1 has a maternal effect on Hox gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfa924a4059fdbdc979cd7f2af94265d
https://doi.org/10.1101/2021.09.08.459528
https://doi.org/10.1101/2021.09.08.459528
Autor:
Fabrice Prin, Shifeng Xue, Yvonne D. Krom, Benetti N, Matthew E. Ritchie, Andrew Keniry, Natasha Jansz, de Greef Jc, Bouwman Lf, Tamara Beck, den Hamer B, Hannah Vanyai, Kelan Chen, Timothy J. Mohun, Edwina McGlinn, Tapia del Fierro A, James M. Murphy, Kelsey Breslin, van der Hoorn D, Harald Oey, Marnie E. Blewitt, Alexandra D. Gurzau, Lucia Daxinger, van der Maarel Sm, Wanigasuriya I, Bruno Reversade, Nguyen Ly Tt
The interplay between 3D chromatin architecture and gene silencing is incompletely understood. Here, we report a novel point mutation in the non-canonical SMC protein SMCHD1 that enhances its silencing capacity at endogenous developmental targets and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122339533082382fd1db20eccc936dfd
https://doi.org/10.1101/2021.05.12.443934
https://doi.org/10.1101/2021.05.12.443934
Autor:
Kelsey Breslin, Michael B. Clark, Marnie E. Blewitt, Shian Su, Ricardo De Paoli-Iseppi, Yair David Joseph Prawer, Xueyi Dong, Matthew E. Ritchie, Hasaru Kariyawasam, Luyi Tian, Megan Iminitoff, Quentin Gouil, Charity W. Law
Publikováno v:
NAR Genomics and Bioinformatics
Application of Oxford Nanopore Technologies’ long-read sequencing platform to transcriptomic analysis is increasing in popularity. However, such analysis can be challenging due to the high sequence error and small library sizes, which decreases qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe69aa1bd5008f7dde5b19bcb9c73110
https://doi.org/10.1093/nargab/lqab028
https://doi.org/10.1093/nargab/lqab028