Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kelsey A. Pilewski"'
Autor:
Kentaro Tohma, Michael Landivar, Lauren A. Ford-Siltz, Kelsey A. Pilewski, Joseph A. Kendra, Sandra Niendorf, Gabriel I. Parra
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 5, Pp 1026-1029 (2024)
Norovirus is a major cause of acute gastroenteritis; GII.4 is the predominant strain in humans. Recently, 2 new GII.4 variants, Hong Kong 2019 and San Francisco 2017, were reported. Characterization using GII.4 monoclonal antibodies and serum demonst
Externí odkaz:
https://doaj.org/article/d8de163ef1e64170bf73b0c56eb0b61f
Autor:
Kelsey A. Pilewski, Steven Wall, Simone I. Richardson, Nelia P. Manamela, Kaitlyn Clark, Tandile Hermanus, Elad Binshtein, Rohit Venkat, Giuseppe A. Sautto, Kevin J. Kramer, Andrea R. Shiakolas, Ian Setliff, Jordan Salas, Rutendo E. Mapengo, Naveen Suryadevara, John R. Brannon, Connor J. Beebout, Rob Parks, Nagarajan Raju, Nicole Frumento, Lauren M. Walker, Emilee Friedman Fechter, Juliana S. Qin, Amyn A. Murji, Katarzyna Janowska, Bhishem Thakur, Jared Lindenberger, Aaron J. May, Xiao Huang, Salam Sammour, Priyamvada Acharya, Robert H. Carnahan, Ted M. Ross, Barton F. Haynes, Maria Hadjifrangiskou, James E. Crowe, Jr., Justin R. Bailey, Spyros Kalams, Lynn Morris, Ivelin S. Georgiev
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112044- (2023)
Summary: Despite prolific efforts to characterize the antibody response to human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) mono-infections, the response to chronic co-infection with these two ever-evolving viruses is poorly un
Externí odkaz:
https://doaj.org/article/1510f5933b314ee292c1c7de93695a93
Autor:
Lauren A. Ford-Siltz, Kentaro Tohma, Gabriela S. Alvarado, Joseph A. Kendra, Kelsey A. Pilewski, James E. Crowe, Gabriel I. Parra
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Human noroviruses are the major viral cause of acute gastroenteritis around the world. Although norovirus symptoms are in most cases mild and self-limited, severe and prolonged symptoms can occur in the elderly and in immunocompromised individuals. T
Externí odkaz:
https://doaj.org/article/4a75487ab0e4486284fccc0de72053b2
Autor:
Lauren M. Walker, Andrea R. Shiakolas, Rohit Venkat, Zhaojing Ariel Liu, Steven Wall, Nagarajan Raju, Kelsey A. Pilewski, Ian Setliff, Amyn A. Murji, Rebecca Gillespie, Nigel A. Makoah, Masaru Kanekiyo, Mark Connors, Lynn Morris, Ivelin S. Georgiev
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Development of novel technologies for the discovery of human monoclonal antibodies has proven invaluable in the fight against infectious diseases. Among the diverse antibody repertoires elicited by infection or vaccination, often only rare antibodies
Externí odkaz:
https://doaj.org/article/b4cc54924c22433d9477b4b78981ae3b
Autor:
Andrea R. Shiakolas, Kevin J. Kramer, Daniel Wrapp, Simone I. Richardson, Alexandra Schäfer, Steven Wall, Nianshuang Wang, Katarzyna Janowska, Kelsey A. Pilewski, Rohit Venkat, Robert Parks, Nelia P. Manamela, Nagarajan Raju, Emilee Friedman Fechter, Clinton M. Holt, Naveenchandra Suryadevara, Rita E. Chen, David R. Martinez, Rachel S. Nargi, Rachel E. Sutton, Julie E. Ledgerwood, Barney S. Graham, Michael S. Diamond, Barton F. Haynes, Priyamvada Acharya, Robert H. Carnahan, James E. Crowe, Jr., Ralph S. Baric, Lynn Morris, Jason S. McLellan, Ivelin S. Georgiev
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 6, Pp 100313- (2021)
Summary: The continual emergence of novel coronaviruses (CoV), such as severe acute respiratory syndrome-(SARS)-CoV-2, highlights the critical need for broadly reactive therapeutics and vaccines against this family of viruses. From a recovered SARS-C
Externí odkaz:
https://doaj.org/article/855d316603ff4ff6bce75cfb57c2d1a1
Publikováno v:
Vaccines, Vol 9, Iss 9, p 964 (2021)
Vaccination remains one of the most successful medical interventions in history, significantly decreasing morbidity and mortality associated with, or even eradicating, numerous infectious diseases. Although traditional immunization strategies have re
Externí odkaz:
https://doaj.org/article/b07b6ace652f43ba910b07117de7a427
Autor:
Gabriel I. Parra, Kentaro Tohma, Lauren A. Ford-Siltz, Patricia Eguino, Joseph A. Kendra, Kelsey A. Pilewski, Yamei Gao
Publikováno v:
J Virol
Norovirus is a major human pathogen that can cause severe gastroenteritis in vulnerable populations. The extensive viral diversity presented by human noroviruses constitutes a major roadblock for the development of effective vaccines. In addition to
Autor:
Andrea R. Shiakolas, Kevin J. Kramer, Nicole V. Johnson, Steven C. Wall, Naveenchandra Suryadevara, Daniel Wrapp, Sivakumar Periasamy, Kelsey A. Pilewski, Nagarajan Raju, Rachel Nargi, Rachel E. Sutton, Lauren M. Walker, Ian Setliff, James E. Crowe, Alexander Bukreyev, Robert H. Carnahan, Jason S. McLellan, Ivelin S. Georgiev
Publikováno v:
Nature Biotechnology. 40:1270-1275
Autor:
Rachel E. Sutton, Alexander Bukreyev, James E. Crowe, Robert H. Carnahan, Nagarajan Raju, Jason S. McLellan, Kevin J Kramer, Rachel S. Nargi, Lauren M. Walker, Sivakumar Periasamy, Naveenchandra Suryadevara, Ivelin S. Georgiev, Ian Setliff, Andrea R. Shiakolas, Daniel Wrapp, Kelsey A. Pilewski, Nicole V. Johnson
Publikováno v:
bioRxiv : the preprint server for biology.
SARS-CoV-2 therapeutic antibody discovery efforts have met with notable success but have been associated with a generally inefficient process, requiring the production and characterization of exceptionally large numbers of candidates for the identifi
Autor:
Andrea R, Shiakolas, Kevin J, Kramer, Nicole V, Johnson, Steven C, Wall, Naveenchandra, Suryadevara, Daniel, Wrapp, Sivakumar, Periasamy, Kelsey A, Pilewski, Nagarajan, Raju, Rachel, Nargi, Rachel E, Sutton, Lauren M, Walker, Ian, Setliff, James E, Crowe, Alexander, Bukreyev, Robert H, Carnahan, Jason S, McLellan, Ivelin S, Georgiev
Publikováno v:
bioRxiv
Although several monoclonal antibodies (mAbs) targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been approved for coronavirus disease 2019 (COVID-19) therapy, development was generally inefficient, with lead generation often