Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kelsey A Herrmann"'
Autor:
Kelsey A Herrmann, Yizhou Liu, Arnau Llobet-Rosell, Colleen N McLaughlin, Lukas J Neukomm, Jaeda C Coutinho-Budd, Heather T Broihier
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010257 (2022)
Elucidating signal transduction mechanisms of innate immune pathways is essential to defining how they elicit distinct cellular responses. Toll-like receptors (TLR) signal through their cytoplasmic TIR domains which bind other TIR domain-containing a
Externí odkaz:
https://doaj.org/article/6f3f608def3c433c8f3eea08c64995cb
Autor:
Kendall M. Hoover, Scott J. Gratz, Nova Qi, Kelsey A. Herrmann, Yizhou Liu, Jahci J. Perry-Richardson, Pamela J. Vanderzalm, Kate M. O’Connor-Giles, Heather T. Broihier
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Activity-dependent pathways are important for synapse function but the molecular links to synapse function are not clear. The authors show that the Ca2 + channel subunit α2δ-3 provides an extracellular scaffold for autocrine BMP signalling at the D
Externí odkaz:
https://doaj.org/article/a1043f4b84eb401ca0ba1c3cdf432be5
Publikováno v:
Current Opinion in Neurobiology. 51:70-79
Although retrograde neurotrophin signaling has provided an immensely influential paradigm for understanding growth factor signaling in the nervous system, recent studies indicate that growth factors also signal via cell-autonomous, or autocrine, mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4ffa5a81b4208c6967dfe1a5d62610
https://doi.org/10.1016/j.conb.2018.03.002
https://doi.org/10.1016/j.conb.2018.03.002
Autor:
Michael E. Barish, Siranush Argalian Herculian, Lucy Ghoda, Marianne Z. Metz, Leanne Goldstein, Christine E. Brown, Jennifer Gutierrez, Russell Rockne, Kelsey A. Herrmann, Alexander J. Annala, Karen S. Aboody, Margarita Gutova, Rex Moats, Revathiswari Tirughana, Soraya Aramburo, Yang Tang
Publikováno v:
Stem Cells Translational Medicine
Engineered neural stem cells (NSCs) intrinsically migrating to brain tumors offer a promising mechanism for local therapeutic delivery. However, difficulties in quantitative assessments of NSC migration and in estimates of tumor coverage by diffusibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3dd973e85818adcccb12d0adc7f3c1
https://doi.org/10.1002/sctm.16-0397
https://doi.org/10.1002/sctm.16-0397
Autor:
Kate O’Connor-Giles, Kelsey A. Herrmann, Scott J Gratz, Pamela J. Vanderzalm, Jahci J. Perry-Richardson, Kendall M. Hoover, Heather T. Broihier, Yizhou Liu, Nova Qi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Synapses are highly specialized for neurotransmitter signaling, yet activity-dependent growth factor release also plays critical roles at synapses. While efficient neurotransmitter signaling relies on precise apposition of release sites and neurotran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a74a8472cf68d9032298e3963182f4e
https://doi.org/10.1038/s41467-019-13165-7
https://doi.org/10.1038/s41467-019-13165-7
Autor:
Mette L. Johansen, Bernadette O. Erokwu, James P. Basilion, Susann M Brady-Kalnay, Mark A. Griswold, Christopher A Flask, Kelsey A. Herrmann, Vikas Gulani
Publikováno v:
Translational Oncology, Vol 9, Iss 2, Pp 147-154 (2016)
Human brain tumors such as glioblastomas are typically detected using conventional, nonquantitative magnetic resonance imaging (MRI) techniques, such as T2-weighted and contrast enhanced T1-weighted MRI. In this manuscript, we tested whether dynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cda207176bfe963aeefb9fbb823b4d
Molecular Imaging of Tumors Using a Quantitative T1 Mapping Technique via Magnetic Resonance Imaging
Autor:
Vikas Gulani, Zheng-Rong Lu, Richard S. Agnes, Christopher A Flask, Susann M. Brady-Kalnay, Sonya E.L. Craig, Ying Gao, Kelsey A. Herrmann, Mette L. Johansen, Michael Howell, Bernadette O. Erokwu, James P. Basilion, Jonathan K. Pokorski, Jason Vincent, Lan Lu, Mark A. Griswold
Publikováno v:
Diagnostics
Volume 5
Issue 3
Pages 318-332
Diagnostics, Vol 5, Iss 3, Pp 318-332 (2015)
Volume 5
Issue 3
Pages 318-332
Diagnostics, Vol 5, Iss 3, Pp 318-332 (2015)
Magnetic resonance imaging (MRI) of glioblastoma multiforme (GBM) with molecular imaging agents would allow for the specific localization of brain tumors. Prior studies using T 1-weighted MR imaging demonstrated that the SBK2-Tris-(Gd-DOTA)3 molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b253154198156788a7d54b7657e67132
http://europepmc.org/articles/PMC4589153
http://europepmc.org/articles/PMC4589153
Preclinical MR fingerprinting (MRF) at 7 T: effective quantitative imaging for rodent disease models
Autor:
Yun Jiang, Mitchell L. Drumm, Yong Chen, Jason Vincent, Katherine MacRae Dell, Ying Gao, Dan Ma, Christopher A Flask, Lan Lu, Mark A. Griswold, Susann M. Brady-Kalnay, Kelsey A. Herrmann
Publikováno v:
NMR in Biomedicine. 28:384-394
High field, preclinical magnetic resonance imaging (MRI) scanners are now commonly used to quantitatively assess disease status and efficacy of novel therapies in a wide variety of rodent models. Unfortunately, conventional MRI methods are highly sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35ff00b6971a0db836792b71c7abbf54
https://doi.org/10.1002/nbm.3262
https://doi.org/10.1002/nbm.3262
Autor:
K Mittelholtz, Alexander J. Annala, Rex Moats, Joseph Najbauer, Yelena Abramyants, Seung U. Kim, Kelsey A. Herrmann, Karen S. Aboody, X-H Shi, Michael E. Barish, Melvin Blanchard, Timothy W. Synold, Vazgen Khankaldyyan, Margarita Gutova, Massimo D'Apuzzo, Gregory M. Shackleford
Publikováno v:
Gene therapy
Medulloblastoma is a heterogeneous diffuse neoplasm that can be highly disseminated, and is the most common malignant childhood brain tumor. Although multimodal treatments have improved survival rates for patients with medulloblastoma, these tumors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee14e5a0e4d459facb16b797628a7d4
http://europepmc.org/articles/PMC4149468
http://europepmc.org/articles/PMC4149468
Autor:
Christine E. Brown, Joseph Najbauer, Seung U. Kim, Alexander J. Annala, Yelena Abramyants, Maciej S. Lesniak, Massimo D'Apuzzo, Lucy Ghoda, Megan Gilchrist, Karen S. Aboody, Kelsey A. Herrmann, Marianne Z. Metz, Vazgen Khankaldyyan, Joseph A. Frank, Michael E. Barish, M. Suzette Blanchard, Margarita Gutova, Rex Moats
Publikováno v:
Stem cells translational medicine. 2(10)
Numerous stem cell-based therapies are currently under clinical investigation, including the use of neural stem cells (NSCs) as delivery vehicles to target therapeutic agents to invasive brain tumors. The ability to monitor the time course, migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df81a2e9bb62fc92f0b8988893f732f
https://pubmed.ncbi.nlm.nih.gov/24014682
https://pubmed.ncbi.nlm.nih.gov/24014682