NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease

Autor: Schwerd, T, Bryant, R V, Pandey, S, Capitani, M, Meran, L, Cazier, J-B, Jung, J, Mondal, K, Parkes, M, Mathew, C G, Fiedler, K, McCarthy, D J, WGS500 Consortium, Oxford IBD cohort study investigators, COLORS in IBD group investigators, UK IBD Genetics Consortium, Sullivan, P B, Rodrigues, A, Travis, S P L, Moore, C, Sambrook, J, Ouwehand, W H, Roberts, D J, Danesh, J, INTERVAL Study, Russell, R K, Wilson, D C, Kelsen, J R, Cornall, R, Denson, L A, Braegger, C, et al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______885::77cc4a2b5b4e558264729705f2b9d0ed
https://www.zora.uzh.ch/id/eprint/167357/

NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease.

Autor: Schwerd T; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Dr von Hauner Children's Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany., Bryant RV; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; University of Adelaide, Adelaide, South Australia, Australia., Pandey S; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Capitani M; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Meran L; The Francis Crick Institute, London, UK., Cazier JB; The Wellcome Trust Centre for Human Genetics, Oxford, UK., Jung J; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Mondal K; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Parkes M; Inflammatory Bowel Disease Research Group, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK., Mathew CG; Department of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital London, London, UK., Fiedler K; SickKids Inflammatory Bowel Disease Center and Cell Biology Program, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., McCarthy DJ; The Wellcome Trust Centre for Human Genetics, Oxford, UK., Sullivan PB; Department of Paediatrics, University of Oxford, Oxford, UK., Rodrigues A; Department of Paediatrics, University of Oxford, Oxford, UK., Travis SPL; Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Moore C; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Sambrook J; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Ouwehand WH; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, Cambridge, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Roberts DJ; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant-Oxford Centre, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK., Danesh J; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Russell RK; Department of Paediatric Gastroenterology, The Royal Hospital for Children, Glasgow, UK., Wilson DC; Royal Hospital for Sick Children, Edinburgh, UK.; Child Life and Health, University of Edinburgh, Edinburgh, UK., Kelsen JR; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Cornall R; Centre for Cellular and Molecular Physiology, University of Oxford, Oxford, UK., Denson LA; Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Kugathasan S; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Knaus UG; Conway Institute, School of Medicine, University College Dublin, Dublin, Ireland.; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland., Serra EG; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Anderson CA; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Duerr RH; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA., McGovern DP; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Cho J; Icahn School of Medicine, Mount Sinai Hospital, New York, New York, USA., Powrie F; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Li VS; The Francis Crick Institute, London, UK., Muise AM; SickKids Inflammatory Bowel Disease Center and Cell Biology Program, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Uhlig HH; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; Department of Paediatrics, University of Oxford, Oxford, UK.

Publikováno v: Mucosal immunology [Mucosal Immunol] 2018 Mar; Vol. 11 (2), pp. 562-574. Date of Electronic Publication: 2017 Nov 01.