Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Kelong, Fan"'
Autor:
Shaobin He, Long Ma, Qionghua Zheng, Zhuoran Wang, Wei Chen, Zihang Yu, Xiyun Yan, Kelong Fan
Publikováno v:
Bioactive Materials, Vol 42, Iss , Pp 284-298 (2024)
The abundance of molecules on early Earth likely enabled a wide range of prebiotic chemistry, with peptides playing a key role in the development of early life forms and the evolution of metabolic pathways. Among peptides, those with enzyme-like acti
Externí odkaz:
https://doaj.org/article/7c01e0b75dc1414aa3ad3239bb37a04c
Publikováno v:
Nano Biomedicine and Engineering, Vol 16, Iss 1, Pp 28-47 (2024)
In the past decade, nanozymes - a unique class of nanomaterials with inherent enzyme-mimetic properties - have fascinated researchers, revealing unexpected enzyme-like activity of nanomaterials previously considered biologically inert. In particular,
Externí odkaz:
https://doaj.org/article/b3b3ae505fff4404969a1fda85ba31a3
Ultrasmall metal alloy nanozymes mimicking neutrophil enzymatic cascades for tumor catalytic therapy
Autor:
Xiangqin Meng, Huizhen Fan, Lei Chen, Jiuyang He, Chaoyi Hong, Jiaying Xie, Yinyin Hou, Kaidi Wang, Xingfa Gao, Lizeng Gao, Xiyun Yan, Kelong Fan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Developing strategies that emulate the killing mechanism of neutrophils, which involves the enzymatic cascade of superoxide dismutase (SOD) and myeloperoxidase (MPO), shows potential as a viable approach for cancer therapy. Nonetheless, util
Externí odkaz:
https://doaj.org/article/e860d3f1339e4d29aca1f365038bcb98
Autor:
Long Ma, Jia-Jia Zheng, Ning Zhou, Ruofei Zhang, Long Fang, Yili Yang, Xingfa Gao, Chunying Chen, Xiyun Yan, Kelong Fan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Biominerals, the inorganic minerals of organisms, are known mainly for their physical property-related functions in modern living organisms. Our recent discovery of the enzyme-like activities of nanomaterials, coined as nanozyme, inspires th
Externí odkaz:
https://doaj.org/article/26622678a297478c81c52aca6480faef
Autor:
Wei Jiang, Xinyue Hou, Yuanbo Qi, Zhigang Wang, Ying Liu, Xuejiao J. Gao, Tingting Wu, Jiancheng Guo, Kelong Fan, Wenjun Shang
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Oxidative stress induced by excess reactive oxygen species (ROS) is a primary pathogenic cause of acute kidney injury (AKI). Development of an effective antioxidation system to mitigate oxidative stress for alleviating AKI remains to be inve
Externí odkaz:
https://doaj.org/article/32e596ce3ff4473f880457bb8c97a845
Autor:
Wei Jiang, Qing Li, Ruofei Zhang, Jianru Li, Qianyu Lin, Jingyun Li, Xinyao Zhou, Xiyun Yan, Kelong Fan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Nanomedicine-based anti-neuroinflammation strategy has become a promising dawn of Parkinson’s disease (PD) treatment. However, there are significant gaps in our understanding of the therapeutic mechanisms of antioxidant nanomedicines conce
Externí odkaz:
https://doaj.org/article/10b847de1b3f427a802f494890fcba43
Autor:
Yongjuan Li, Xinran Zhu, Ya Dong, Yang Yang, Danyang Shen, Zhenzhen Li, Rui Li, Xiaowei Dang, Zhihai Qin, Kelong Fan
Publikováno v:
Advanced NanoBiomed Research, Vol 4, Iss 3, Pp n/a-n/a (2024)
Photothermal therapy (PTT) has emerged as a promising approach for tumor ablation utilizing hyperthermia offers several advantages, including non‐invasiveness, spatiotemporal controllability, and notable therapeutic efficacy. However, the clinical
Externí odkaz:
https://doaj.org/article/5ff37eb41a324aceab06742d774258f1
Autor:
Xiaonan Wang, Ting Liu, Mengxia Chen, Qian Liang, Jing Jiang, Lei Chen, Kelong Fan, Jinhua Zhang, Lizeng Gao
Publikováno v:
Advanced Science, Vol 11, Iss 6, Pp n/a-n/a (2024)
Abstract Iron single‐atom nanozymes represent a promising artificial enzyme with superior activity owing to uniform active sites that can precisely mimic active center of nature enzymes. However, current synthetic strategies are hard to guarantee e
Externí odkaz:
https://doaj.org/article/fc0ca010edd14b6f83d4e2c79e121c61
Publikováno v:
Advanced Science, Vol 11, Iss 3, Pp n/a-n/a (2024)
Abstract Hydrogels are prevailing drug delivery depots to improve antitumor efficacy and reduce systemic toxicity. However, the application of conventional free drug‐loaded hydrogel is hindered by poor drug penetration in solid tumors. Here, an inj
Externí odkaz:
https://doaj.org/article/2935d7ae3b3f4a0cb7821a635f043d67
Autor:
Jia Wang, Qingpeng Xie, Haoyue Song, Xiaohang Chen, Xiaoxuan Zhang, Xiangyu Zhao, Yujia Hao, Yuan Zhang, Huifei Li, Na Li, Kelong Fan, Xing Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract The emergence of human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses significant challenges to global public health. Despite the extensive efforts of researchers worldwide, there remains considerable opportunities for im
Externí odkaz:
https://doaj.org/article/c410a0028f0046188e0102b10575d811