Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Kelly Z Young"'
Autor:
Soo Jung Lee, Akhil Kondepudi, Kelly Z Young, Xiaojie Zhang, Naw May Pearl Cartee, Jijun Chen, Krystal Yujin Jang, Gang Xu, Jimo Borjigin, Michael M Wang
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281094 (2023)
The most common inherited cause of vascular dementia and stroke, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), is caused by mutations in NOTCH3. Post-translationally altered NOTCH3 accumulates i
Externí odkaz:
https://doaj.org/article/a7b0fc3052af4bf6ba28219087b29fed
Autor:
Kelly Z. Young, Carolina Rojas Ramírez, Simon G. Keep, John R. Gatti, Soo Jung Lee, Xiaojie Zhang, Magdalena I. Ivanova, Brandon T. Ruotolo, Michael M. Wang
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Specific cysteine residue alterations and quaternary structures are induced by CADASIL mutations in NOTCH3, which are found to induce oligomeric states, altered disulphide bonding, increased free thiols and reduced protein stability.
Externí odkaz:
https://doaj.org/article/60e1780b1a8f414998df307a93fc4f7e
Autor:
Kelly Z. Young, BA, Sara L. Fossum, MD, PhD, Lori Lowe, MD, Tobias Else, MD, Leslie A. Fecher, MD, Hakan Demirci, MD, Kelly B. Cha, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 6, Iss 6, Pp 563-566 (2020)
Externí odkaz:
https://doaj.org/article/a995474b3ca64ffe8e3d7ab477e635fa
Publikováno v:
JAAD Case Reports. 31:49-52
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3671 (2022)
Cysteine oxidation states of extracellular proteins participate in functional regulation and in disease pathophysiology. In the most common inherited dementia, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
Externí odkaz:
https://doaj.org/article/285299e2db0544cdb6ad5ce06037cc75
Publikováno v:
Skin Appendage Disorders. 9:30-33
Introduction: Dermatologic and systemic conditions affecting nails are common, but nail pathology education in medical school curricula is limited. We created and evaluated the efficacy of a case-based module on nail pathologies in a medical student
Publikováno v:
Frontiers in Immunology. 14
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that can manifest with abscesses, sinus tracts, and scarring in the intertriginous areas of the body. HS is characterized by immune dysregulation, featuring elevated levels of mye
Publikováno v:
Journal of Clinical Investigation. 133
Publikováno v:
Experimental Dermatology.
Publikováno v:
The American Journal of Pathology. 191:1871-1887