Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kelly T. Huynh"'
Autor:
Kelly T. Huynh, Selena Y. Lin, Shu-Ching Chang, Sharon K. Huang, Diego M. Marzese, Richard B. Lanman, Matthew P. Salomon, Dave S.B. Hoon, AmirAli Talasaz
Publikováno v:
JCO Precis Oncol
Purpose Hotspot blood cell-free DNA (cfDNA) biomarker assays have limited utility in profiling tumor heterogeneity and burden and in capturing regional metastasis with low disease burden in patients with melanoma. We investigated the utility of a sen
Autor:
Annabelle Teng, Sarah Vitug, Stacey L. Stern, Mark B. Faries, Jihey Lee, Leland J. Foshag, Briana J. Lau, Kelly T. Huynh, David Y. Lee
Publikováno v:
Annals of Surgical Oncology. 23:1012-1018
The status of the sentinel lymph node in melanoma is an important prognostic factor. The clinical predictors and implications of false-negative (FN) biopsy remain debatable. We compared patients with positive sentinel lymph node biopsy (SNB) [true po
Autor:
Daniel D. Kirchoff, Kelly T. Huynh, Devin C. Flaherty, Mark B. Faries, Leland J. Foshag, David Y. Lee, Anton J. Bilchik, Jihey Lee, Gary B. Deutsch
Publikováno v:
The American Surgeon. 81:1005-1009
Surgical resection of metastases to the adrenal gland can improve overall survival of patients with stage IV melanoma, but its relative value with respect to current nonsurgical therapies is unknown. We hypothesized that surgery remains an optimal fi
Autor:
Anton J. Bilchik, Kelly T. Huynh
Publikováno v:
The Cancer Journal. 21:11-16
The tumor status of the regional lymph nodes is the most important prognostic indicator in colorectal cancer (CRC), as it is in other solid tumors. Sentinel lymph node biopsy (SLNB), which has profoundly impacted the treatment of melanoma and breast
Publikováno v:
Cancer Letters. 342:170-177
Epigenetic aberrations have been associated with cutaneous melanoma tumorigenesis and progression including dysregulated DNA gene promoter region methylation, histone modification, and microRNA. Several of these major epigenetic aberrations have been
Publikováno v:
Journal of the American College of Surgeons. 223(3)
Appropriate use of laparoscopic adrenalectomy (LA) for adrenocortical carcinoma (ACC) remains controversial because complete resection with negative margins is the best chance for potential cure. This study compared the oncologic outcomes and overall
Autor:
Kelly T. Huynh, Dave S.B. Hoon
The field of genomic biomarkers in melanoma has evolved dramatically in the past few decades. Whereas much of the prior focus has been on molecular assessment of tumor tissue, circulating tumor cells (CTCs) and cell-free circulating tumor DNA (ctDNA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d25f12b6cb7f22cdc096da9f41b5dd1
https://europepmc.org/articles/PMC5326707/
https://europepmc.org/articles/PMC5326707/
Autor:
Parisa Mirzadehgan, Myung-Shin Sim, Travis Kidner, Alice P. Chung, Armando E. Giuliano, Kelly T. Huynh
Publikováno v:
Journal of the American College of Surgeons. 215:137-146
There is controversy about whether breast conserving therapy (BCT) should be contraindicated in multifocal (MF) breast cancer. Few studies have reported on the oncologic safety of BCT in MF breast cancer.We reviewed a prospective database of 1,169 wo
Autor:
Armando E. Giuliano, Hideyuki Okano, Naofumi Kagara, Dave S.B. Hoon, Kelly Chong, Myung-Shin Sim, Christine Kuo, Kelly T. Huynh, David Elashoff
Publikováno v:
The American Journal of Pathology. 181:257-267
Expression of specific breast cancer stem cells (BCSCs) is seen in aggressive tumors, but their regulation is unclear. Epigenetic changes influence gene expression and are implicated in breast cancer progression. We hypothesized that promoter methyla
Publikováno v:
Expert Review of Molecular Diagnostics. 12:371-382
Increasingly, breast cancer is being recognized as a heterogeneous disease comprised of molecularly and phenotypically distinct intrinsic tumor subtypes with different clinical outcomes. This biological heterogeneity has significant implications, par