Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Kelly T. Hughes"'
FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria
Autor:
Manuel Halte, Ekaterina P. Andrianova, Christian Goosmann, Fabienne F. V. Chevance, Kelly T. Hughes, Igor B. Zhulin, Marc Erhardt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The bacterial flagellum, which facilitates motility, is composed of ~20 structural proteins organized into a long extracellular filament connected to a cytoplasmic rotor-stator complex via a periplasmic rod. Flagellum assembly is regulated b
Externí odkaz:
https://doaj.org/article/1fae30fb18c340a380f649d28be01a86
Autor:
Julia A. Horstmann, Michele Lunelli, Hélène Cazzola, Johannes Heidemann, Caroline Kühne, Pascal Steffen, Sandra Szefs, Claire Rossi, Ravi K. Lokareddy, Chu Wang, Laurine Lemaire, Kelly T. Hughes, Charlotte Uetrecht, Hartmut Schlüter, Guntram A. Grassl, Theresia E. B. Stradal, Yannick Rossez, Michael Kolbe, Marc Erhardt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Flagellin proteins of Salmonella flagella are methylated. Here, the authors show that flagellin methylation facilitates adhesion of Salmonella to hydrophobic host-cell surfaces, and contributes to efficient gut colonization and host infection.
Externí odkaz:
https://doaj.org/article/a2e29bfad3e243b1b5b15ef5ca3af75a
Genetic Analysis of the Salmonella FliE Protein That Forms the Base of the Flagellar Axial Structure
Autor:
Jordan J. Hendriksen, Hee Jung Lee, Alexander J. Bradshaw, Keiichi Namba, Fabienne F. V. Chevance, Tohru Minamino, Kelly T. Hughes
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
The FliE component of the bacterial flagellum is the first protein secreted through the flagellar type III secretion system (fT3SS) that is capable of self-assembly into the growing bacterial organelle. The FliE protein plays dual roles in the assemb
Externí odkaz:
https://doaj.org/article/e9b78c88bae549c6a5e16117a5de1539
Autor:
Guillaume Paradis, Fabienne F. V. Chevance, Willisa Liou, Thibaud T. Renault, Kelly T. Hughes, Simon Rainville, Marc Erhardt
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Many bacteria swim through liquids or crawl on surfaces by rotating long appendages called flagella. Flagellar filaments are assembled from thousands of subunits that are exported through a narrow secretion channel and polymerize beneath a c
Externí odkaz:
https://doaj.org/article/9d48816ce76f42f4a0ce35b547ad1dd8
Autor:
Takashi Fujii, Takayuki Kato, Koichi D. Hiraoka, Tomoko Miyata, Tohru Minamino, Fabienne F. V. Chevance, Kelly T. Hughes, Keiichi Namba
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
The bacterial flagellum is a motile organelle that enables bacterial movement. Here the authors explain how the structurally similar flagellum components FlgG and FlgE can give rise to distinct macrostructures—the rod and hook—through subtle diff
Externí odkaz:
https://doaj.org/article/c5b9b41b0a2d454f8275827ce0b51b2c
Autor:
Hanna M. Singer, Marc Erhardt, Andrew M. Steiner, Min-Min Zhang, Doju Yoshikami, Grzegorz Bulaj, Baldomero M. Olivera, Kelly T. Hughes
Publikováno v:
mBio, Vol 3, Iss 3 (2012)
ABSTRACT The structure, assembly, and function of the bacterial flagellum involves about 60 different proteins, many of which are selectively secreted via a specific type III secretion system (T3SS) (J. Frye et al., J. Bacteriol. 188:2233–2243, 200
Externí odkaz:
https://doaj.org/article/832a20cba56b447caad0757b36667181
A unique, rigorous scientific approach to understanding bacterial genetics; inspires readers by providing an opportunity to learn from John Roth's achievements and contributions to bacterial genetics.
Autor:
Bhavana S. Lakshmi, Naeha Subramanian, Ajay Suresh Akhade, Neha Dikshit, Ayub Qadri, Kelly T. Hughes, Shaikh M. Atif
Publikováno v:
Proceedings of the National Academy of Sciences. 117:29811-29822
Inflammasomes have been implicated in the detection and clearance of a variety of bacterial pathogens, but little is known about whether this innate sensing mechanism has any regulatory effect on the expression of stimulatory ligands by the pathogen.
Autor:
Kelly T. Hughes
Publikováno v:
Reference Module in Life Sciences ISBN: 9780128096338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a3637d5999c83bf670622fffe85508f
https://doi.org/10.1016/b978-0-12-822563-9.00082-2
https://doi.org/10.1016/b978-0-12-822563-9.00082-2
Autor:
Kelly T. Hughes
Publikováno v:
Reference Module in Life Sciences ISBN: 9780128096338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a4efe788a0d4be289f67683ec8e415d
https://doi.org/10.1016/b978-0-12-822563-9.00083-4
https://doi.org/10.1016/b978-0-12-822563-9.00083-4