Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kelly T. Carter"'
Autor:
William M. Grady, John M. Inadomi, Yanxin Luo, Andrew M. Kaz, Maria Westerhoff, Polly A. Newcomb, Cornelia M. Ulrich, Christopher I. Li, Paul D. Lampe, Wynn Burke, Kelly T. Carter, Ming Yu, Sean K. Maden, Kit Curtius, William D. Hazelton, Georg E. Luebeck
This file provides a list of drift-related CGI-gene pairs for which methylation is significantly correlated with gene expression (q-value ) in left colon (including rectum) and right colon.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5289f92cf5546594bcfb2716dc9f86
https://doi.org/10.1158/0008-5472.22422023.v1
https://doi.org/10.1158/0008-5472.22422023.v1
Autor:
William M. Grady, John M. Inadomi, Yanxin Luo, Andrew M. Kaz, Maria Westerhoff, Polly A. Newcomb, Cornelia M. Ulrich, Christopher I. Li, Paul D. Lampe, Wynn Burke, Kelly T. Carter, Ming Yu, Sean K. Maden, Kit Curtius, William D. Hazelton, Georg E. Luebeck
This file provides a list of the genomic location, associated genes, proximity to transcription start sites (TSS200 or TSS1500), the number of array probes and number of identified drift probes and the island-level drift rate (regression slopes) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144ae7b2348fbe3169e85789cd879345
https://doi.org/10.1158/0008-5472.22422026.v1
https://doi.org/10.1158/0008-5472.22422026.v1
Autor:
William M. Grady, John M. Inadomi, Yanxin Luo, Andrew M. Kaz, Maria Westerhoff, Polly A. Newcomb, Cornelia M. Ulrich, Christopher I. Li, Paul D. Lampe, Wynn Burke, Kelly T. Carter, Ming Yu, Sean K. Maden, Kit Curtius, William D. Hazelton, Georg E. Luebeck
Many normal tissues undergo age-related drift in DNA methylation, providing a quantitative measure of tissue age. Here, we identify and validate 781 CpG islands (CGI) that undergo significant methylomic drift in 232 normal colorectal tissues and show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfe81d072d3b4d98214b6bb6be3dc85d
https://doi.org/10.1158/0008-5472.c.6511112.v1
https://doi.org/10.1158/0008-5472.c.6511112.v1
Autor:
William M. Grady, Jill S. Barnholtz-Sloan, Yanwen Chen, Nicholas J. Shaheen, Chao-Jen Wong, Maria Westerhoff, Sharmila Anandabapasathy, Dean E. Brenner, Sanford D. Markowitz, Helen R. Moinova, Joseph E. Willis, Apoorva Chandar, Amitabh Chak, Kelly T. Carter, Shelli M. Morris, Andrew M. Kaz, Rachele M. O'Leary, Ming Yu
Supplemental Figure S1: Assessment of precision of pyrosequencing assay for methylated B3GAT2 and ZNF793. Supplemental Figure S2: Correlation of pyrosequencing results with HM450 array beta values.Supplemental Figure S3: Methylation status of B3GAT2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4d95f1274e095f79e0bb852c8f8a50
https://doi.org/10.1158/1055-9965.22437193
https://doi.org/10.1158/1055-9965.22437193
Autor:
William M. Grady, John M. Inadomi, Yanxin Luo, Andrew M. Kaz, Maria Westerhoff, Polly A. Newcomb, Cornelia M. Ulrich, Christopher I. Li, Paul D. Lampe, Wynn Burke, Kelly T. Carter, Ming Yu, Sean K. Maden, Kit Curtius, William D. Hazelton, Georg E. Luebeck
Derivation of adenoma to carcinoma sojourn times, with table S1 showing estimated methylation drift rate parameters and table S2 showing estimated sojourn times for three tissue age models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387086829e2f16edc62f32ab39e210d5
https://doi.org/10.1158/0008-5472.22422017.v1
https://doi.org/10.1158/0008-5472.22422017.v1
Autor:
William M. Grady, Jill S. Barnholtz-Sloan, Yanwen Chen, Nicholas J. Shaheen, Chao-Jen Wong, Maria Westerhoff, Sharmila Anandabapasathy, Dean E. Brenner, Sanford D. Markowitz, Helen R. Moinova, Joseph E. Willis, Apoorva Chandar, Amitabh Chak, Kelly T. Carter, Shelli M. Morris, Andrew M. Kaz, Rachele M. O'Leary, Ming Yu
Supplemental Table S2: Methylation levels for B3GAT2 and ZNF793 from Human Methylation450 arrays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d589175f20dad46f6d562232a6a2c92
https://doi.org/10.1158/1055-9965.22437187
https://doi.org/10.1158/1055-9965.22437187
Autor:
William M. Grady, Jill S. Barnholtz-Sloan, Yanwen Chen, Nicholas J. Shaheen, Chao-Jen Wong, Maria Westerhoff, Sharmila Anandabapasathy, Dean E. Brenner, Sanford D. Markowitz, Helen R. Moinova, Joseph E. Willis, Apoorva Chandar, Amitabh Chak, Kelly T. Carter, Shelli M. Morris, Andrew M. Kaz, Rachele M. O'Leary, Ming Yu
Supplemental Table S1. Clinical Characteristics of Samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5439d76be6b9a1d37b10e74c4cf0cb2
https://doi.org/10.1158/1055-9965.22437190.v1
https://doi.org/10.1158/1055-9965.22437190.v1
Autor:
Huichuan Yu, Xiaolin Wang, Liangliang Bai, Guannan Tang, Kelly T Carter, Ji Cui, Pinzhu Huang, Li Liang, Yanqing Ding, Muyan Cai, Meijin Huang, Huanliang Liu, Guangwen Cao, Steven Gallinger, Rish K Pai, Daniel D Buchanan, Aung Ko Win, Polly A Newcomb, Jianping Wang, William M Grady, Yanxin Luo
Publikováno v:
J Natl Cancer Inst
Background The current risk stratification system defined by clinicopathological features does not identify the risk of recurrence in early-stage (stage I-II) colorectal cancer (CRC) with sufficient accuracy. We aimed to investigate whether DNA methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1efa32e27cf8449e18cc00b974e736d4
https://europepmc.org/articles/PMC10089593/
https://europepmc.org/articles/PMC10089593/
Autor:
Jeanne Fredrickson, Ting Wang, Victor Moreno, Miguel A. Peinado, Julia Matas, Xianyong Gui, Ming Yu, Thierry Soussi, Rosa Ana Risques, Kelly T. Carter, William M. Grady, Brendan F. Kohrn
While somatic mutations in colorectal cancer (CRC) are well characterized, little is known about the accumulation of cancer mutations in the normal colon prior to cancer. Here we have developed and applied an ultra-sensitive, single-molecule mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92b8d74b6777200406fa8a68aed61839
https://doi.org/10.1101/2021.10.11.21264780
https://doi.org/10.1101/2021.10.11.21264780
Autor:
Ming Yu, William M. Grady, Miguel A. Peinado, Kelly T. Carter, Ting Wang, Júlia Matas Gironella, Jeanne Fredickson, Brendan F. Kohrn, Rosa Ana Risques
Publikováno v:
Cancer Research. 81:LB231-LB231
Introduction: While somatic mutations in colorectal cancer (CRC) are well characterized, little is known about the accumulation of cancer-associated mutations in normal colon. This knowledge is crucial to understand the origin and evolution of cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ec7ab3aba51e372eb7ca59ce9918584
https://doi.org/10.1158/1538-7445.am2021-lb231
https://doi.org/10.1158/1538-7445.am2021-lb231
