Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kelly S Hayes"'
Autor:
Neima Briggs, Junfei Wei, Leroy Versteeg, Bin Zhan, Brian Keegan, Ashish Damania, Jeroen Pollet, Kelly S Hayes, Coreen Beaumier, Christopher A Seid, Jamie Leong, Richard K Grencis, Maria Elena Bottazzi, K Jagannadha Sastry, Peter J Hotez
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007273 (2018)
Human whipworm (Trichuris trichiura) infects approximately 1 in 15 people worldwide, representing the leading infectious cause of colitis and subsequent, inflammatory bowel disease (IBD). Current control measures focused on mass deworming have had li
Externí odkaz:
https://doaj.org/article/c52d2e12e4f3409e9ebdb58ff06a1b09
Autor:
Kelly S Hayes, Laura J Cliffe, Alison J Bancroft, Simon P Forman, Seona Thompson, Cath Booth, Richard K Grencis
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005708 (2017)
Incidences of infection-related cancers are on the rise in developing countries where the prevalence of intestinal nematode worm infections are also high. Trichuris muris (T. muris) is a murine gut-dwelling nematode that is the direct model for human
Externí odkaz:
https://doaj.org/article/b35adde79d824acbacb81045f7d66043
Autor:
Ashley Houlden, Kelly S Hayes, Allison J Bancroft, John J Worthington, Ping Wang, Richard K Grencis, Ian S Roberts
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125945 (2015)
Trichuris species are a globally important and prevalent group of intestinal helminth parasites, in which Trichuris muris (mouse whipworm) is an ideal model for this disease. This paper describes the first ever highly controlled and comprehensive inv
Externí odkaz:
https://doaj.org/article/ee7c264ff7fa4073901e02f7a81da854
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Genome-scale metabolic models are widely used to enhance our understanding of metabolic features of organisms, host-pathogen interactions and to identify therapeutics for diseases. Here we present iTMU798, the genome-scale metabolic model of
Externí odkaz:
https://doaj.org/article/cec17c831ff347c7b75d0ae58cfd6235
Autor:
María A. Duque-Correa, David Goulding, Faye H. Rodgers, J. Andrew Gillis, Claire Cormie, Kate A. Rawlinson, Allison J. Bancroft, Hayley M. Bennett, Magda E. Lotkowska, Adam J. Reid, Anneliese O. Speak, Paul Scott, Nicholas Redshaw, Charlotte Tolley, Catherine McCarthy, Cordelia Brandt, Catherine Sharpe, Caroline Ridley, Judit Gali Moya, Claudia M. Carneiro, Tobias Starborg, Kelly S. Hayes, Nancy Holroyd, Mandy Sanders, David J. Thornton, Richard K. Grencis, Matthew Berriman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Whipworms are large parasites causing chronic disease in humans and other mammals. Here, the authors show how larvae create tunnels inside the gut lining and reveal the early host response to infection via Isg15 in mice and murine caecaloids.
Externí odkaz:
https://doaj.org/article/86da51cf01e849638b4d23641665bd5e
Autor:
Evelyn Funjika, Stefano A.P. Colombo, Kelly S. Hayes, Mary J. Tozer, Katrina A. Tyrrell, Shanshan Cai, Aduragbemi A. Faniyi, Rebecca K. Shears, Megan Dooley, Yasmine Alshammari, Wafaa Alhazmi, Mushref Assas, Abdullah Almilaibary, Lucy H. Jackson-Jones, David J. Thornton, John J. Worthington, Richard K. Grencis
Publikováno v:
Mucosal Immunology. 16:27-38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfd41d3f23cb8f46ad534547c98ca0ce
https://doi.org/10.1016/j.mucimm.2023.01.004
https://doi.org/10.1016/j.mucimm.2023.01.004
Autor:
Kelly S. Hayes, Richard K. Grencis
Publikováno v:
Parasitology
Trichuris muris is a mouse intestinal parasitic nematode that inhabits the large intestine of its host and induces a strong immune response. The effects of this strong anti-parasite response can be found locally within the intestinal niche and also s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3130536a7c457ec10bd188c184300f01
https://doi.org/10.1017/s0031182021000883
https://doi.org/10.1017/s0031182021000883
Autor:
Jonathan W. Lo, Joana F. Neves, Dominika Hromadová, Kelly S. Hayes, J-H Schroeder, Birgit Strobl, Richard K. Grencis, Graham M. Lord, Katrin Meissl, Emily Read, Luke B. Roberts, C Moreira Heliodoro, Tomasz Zabinski, Rita Antunes Dos Reis, Jane K. Howard
Innate lymphoid cells (ILC) play a significant role in the intestinal immune response and T-bet+ CD127+ group 1 cells (ILC1) have been linked to the pathogenesis of human inflammatory bowel disease (IBD). However, the functional importance of ILC1 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f571cec89e69e64391b4ce6e896ae2ea
https://doi.org/10.1101/2021.06.05.447200
https://doi.org/10.1101/2021.06.05.447200
Autor:
Ana Villegas-Mendez, Maria Z Krauss, Linda V. Sinclair, Kelly S. Hayes, Matthew R. Hepworth, Kevin N. Couper, Richard K. Grencis
Trichuris trichiura (whipworm) is a gastrointestinal nematode that infects approximately 465 million people worldwide. T. muris is used as a tractable model for the human whipworm. In wild type mice, infection with a high dose of T. muris eggs leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c14b2473f725efafa10914b08e9aa91d
https://doi.org/10.1101/2020.11.30.405316
https://doi.org/10.1101/2020.11.30.405316
Autor:
María A. Duque-Correa, David Goulding, Faye H. Rodgers, Claire Cormie, Kate Rawlinson, J. Andrew Gillis, Allison J. Bancroft, Hayley M. Bennett, Magda Lotkowska, Adam J. Reid, Anneliese Speak, Paul Scott, Nicholas Redshaw, Catherine McCarthy, Cordelia Brandt, Catherine Sharpe, Caroline Ridley, Judit Gali Moya, Claudia M. Carneiro, Tobias Starborg, Kelly S. Hayes, Nancy Holroyd, Mandy Sanders, David J. Thornton, Richard K. Grencis, Matthew Berriman
Hundreds of millions of people are infected with whipworms (Trichuris trichiura), large metazoan parasites that live in the caecum and proximal colon. Whipworms inhabit distinct multi-intracellular epithelial burrows that have been described as syncy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::427c77ddab630cff3da5d564c9b9a15d
https://doi.org/10.1101/2020.08.21.261586
https://doi.org/10.1101/2020.08.21.261586