Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kelly R. Locke"'
Autor:
Peter Fleming, Antiopi Varelias, Siok-Keen Tey, Mariapia A. Degli-Esposti, Kelli P. A. MacDonald, Bruce R. Blazar, Fernando Souza-Fonseca-Guimaraes, Rachel D. Kuns, Mark J. Smyth, Kelly R. Locke, Geoffrey R. Hill, Steven W. Lane, Katie E. Lineburg, Nicholas D. Huntington, Iona S. Schuster, Mark D. Bunting
Publikováno v:
Blood. 129:630-642
Allogeneic bone marrow transplantation (allo-BMT) is a curative therapy for hematological malignancies, but is associated with significant complications, principally graft-versus-host disease (GVHD) and opportunistic infections. Natural killer (NK) c
Autor:
Ping Zhang, Bianca E. Teal, Rachel D. Kuns, Antiopi Varelias, Kelli P. A. MacDonald, Mark D. Bunting, Katie E. Lineburg, Christian R. Engwerda, Shaun R. McColl, Leesa F. Wockner, Kelly R. Locke, Kate A. Markey, Gabrielle T. Belz, Geoffrey R. Hill, Kate H. Gartlan, Motoko Koyama, Slavica Vuckovic, Lucie Leveque-El Mouttie, Melody Cheong, Michele W.L. Teng, Siok-Keen Tey, Mark J. Smyth
Publikováno v:
The Journal of Experimental Medicine
Koyama et al. show that GVHD markedly enhances alloantigen presentation within the mesenteric lymph nodes, mediated by donor CD103+CD11b− DCs that migrate from the colon under the influence of CCR7. This antigen presentation imprints gut-homing int
Autor:
Kate H. Gartlan, Ping Zhang, Nicholas D. Huntington, Marta Chesi, Kate A. Markey, Rachel D. Kuns, Kelly R. Locke, Antiopi Varelias, John J. Miles, Mark J. Smyth, Thomas S. Watkins, Slavica Vuckovic, Simone A. Minnie, Geoffrey R. Hill, David D. Smith, Camille Guillerey
Publikováno v:
Blood. 132:2031-2031
Autologous stem cell transplantation (ASCT) remains an important consolidation treatment for multiple myeloma (MM) patients, even in the era of novel agents. The prolongation of plateau-phase induced by ASCT is generally attributed to intensive cytor
Autor:
Ping, Zhang, Jason S, Lee, Kate H, Gartlan, Iona S, Schuster, Iain, Comerford, Antiopi, Varelias, Md Ashik, Ullah, Slavica, Vuckovic, Motoko, Koyama, Rachel D, Kuns, Kelly R, Locke, Kirrilee J, Beckett, Stuart D, Olver, Luke D, Samson, Marcela, Montes de Oca, Fabian, de Labastida Rivera, Andrew D, Clouston, Gabrielle T, Belz, Bruce R, Blazar, Kelli P, MacDonald, Shaun R, McColl, Ranjeny, Thomas, Christian R, Engwerda, Mariapia A, Degli-Esposti, Axel, Kallies, Siok-Keen, Tey, Geoffrey R, Hill
Publikováno v:
Science immunology. 2(10)
Type-1 regulatory T (TR1) cells are Foxp3-negative IL-10-producing CD4+ T cells with potent immune suppressive properties but their requirements for lineage development have remained elusive. Here we show that TR1 cells constitute the most abundant r
Autor:
Philip Hugenholtz, Kelli P. A. MacDonald, Andrea S. Henden, Kate H. Gartlan, Kelly R. Locke, Bruce R. Blazar, Chun Y. Lim, Ping Zhang, Rachel D. Kuns, Sumaira Z. Hasnain, Nancy Lachner, Antiopi Varelias, Kate L. Ormerod, Geoffrey R. Hill, Mark D. Bunting, Motoko Koyama, Michael A. McGuckin, Andrew D. Clouston
Publikováno v:
Publons
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ResearcherID
Donor T cell-derived IL-17A can mediate late immunopathology in graft-versus-host disease (GVHD), however protective roles remain unclear. Using multiple cytokine and cytokine receptor subunit knockout mice we demonstrate that stem cell transplant (S