Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kelly R. Lindblom"'
Publikováno v:
The EMBO Journal
Caspase‐2 has been shown to initiate apoptotic cell death in response to specific intracellular stressors such as DNA damage. However, the molecular mechanisms immediately upstream of its activation are still poorly understood. We combined a caspas
Autor:
Christopher B. Newgard, Alexander C. Robeson, Olga Ilkayeva, Erika Segear Johnson, Sally Kornbluth, Robert Stevens, Kelly R. Lindblom, Joshua L. Andersen
Publikováno v:
Journal of Biological Chemistry. 288:14463-14475
The accumulation of long-chain fatty acids (LCFAs) in non-adipose tissues results in lipid-induced cytotoxicity (or lipoapoptosis). Lipoapoptosis has been proposed to play an important role in the pathogenesis of several metabolic diseases, including
Autor:
Leandi Krüger, Brittany N. Bohinc, Cynthia D. Guy, Guanhua Xie, Marzena Swiderska-Syn, Erika Segear Johnson, Sally Kornbluth, T. De Almeida Pereira, Mariana Verdelho Machado, Kelly R. Lindblom, Anna Mae Diehl, Gregory A. Michelotti, Jérôme Boursier, Gamze Karaca
Publikováno v:
Gut
Gut, BMJ Publishing Group, 2015, 64 (7), pp.1148-1157. ⟨10.1136/gutjnl-2014-307362⟩
Gut, BMJ Publishing Group, 2015, 64 (7), pp.1148-1157. ⟨10.1136/gutjnl-2014-307362⟩
International audience; OBJECTIVE: Caspase-2 is an initiator caspase involved in multiple apoptotic pathways, particularly in response to specific intracellular stressors (eg, DNA damage, ER stress). We recently reported that caspase-2 was pivotal fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19b8b9e765c8c448b92a2035ffcdc10
https://hal.archives-ouvertes.fr/hal-01392300
https://hal.archives-ouvertes.fr/hal-01392300
Autor:
Sally Kornbluth, Kelly R. Lindblom
Publikováno v:
Cell Death ISBN: 9781461493013
Energy balance is essential for cells to function properly and proliferate. Sufficient nutrient quantities are required for energy and the synthesis of building blocks of cellular structures such as lipid membranes, proteins, and nucleic acids. In co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::109d35211a57e5c9d9e3ffc725a507db
https://doi.org/10.1007/978-1-4614-9302-0_9
https://doi.org/10.1007/978-1-4614-9302-0_9
Autor:
M. Arthur Moseley, Kelly R. Lindblom, Sally Kornbluth, Joshua L. Andersen, Erika Segear Johnson, Christopher D. Freel, Lauren R. Lilley, J. Will Thompson, Chih-Sheng Yang
While lysine acetylation in the nucleus is well characterized, comparatively little is known about its significance in cytoplasmic signaling. Here we show that inhibition of the Sirt1 deacetylase, which is primarily cytoplasmic in cancer cell lines,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f55a03cce9a3a48d2ae1af89b3e838c
https://europepmc.org/articles/PMC3417139/
https://europepmc.org/articles/PMC3417139/