Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression.

Autor: Patrick R Secor, Laura K Jennings, Garth A James, Kelly R Kirker, Elinor Delancey Pulcini, Kate McInnerney, Robin Gerlach, Tom Livinghouse, Jonathan K Hilmer, Brian Bothner, Philip Fleckman, John E Olerud, Philip S Stewart

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e40973 (2012)

Staphylococcus aureus biofilms are associated with chronic skin infections and are orders of magnitude more resistant to antimicrobials and host responses. S. aureus contains conserved nonribosomal peptide synthetases that produce the cyclic dipeptid

Externí odkaz: https://doaj.org/article/e8fec58d4d754c1db632c5dc357ec1ae

Streptococcus mutans and Actinomyces naeslundii Interaction in Dual-Species Biofilm

Autor: Cristiane Yumi Koga-Ito, Fernanda Salloume Sampaio Bonafé, Aline Leite de Farias, Rosa Virginia Dutra de Oliveira, Kelly R. Kirker, Denise Madalena Palomari Spolidorio, Garth A. James, Fernanda Lourenção Brighenti

Publikováno v: Microorganisms
Volume 8
Issue 2
Microorganisms, Vol 8, Iss 2, p 194 (2020)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

The study of bacterial interaction between Streptococcus mutans and Actinomyces naeslundii may disclose important features of biofilm interspecies relationships. The aim of this study was to characterize&mdash
with an emphasis on biofilm formati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42185d9ebb11d47407c1447f8b4d865d

In vitro studies evaluating the effects of biofilms on wound-healing cells: a review

Autor: Garth A. James, Kelly R. Kirker

Publikováno v: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 125(4)

Chronic wounds are characterized as wounds that have failed to proceed through the well-orchestrated healing process and have remained open for months to years. Open wounds are at risk for colonization by opportunistic pathogens. Bacteria that coloni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3056b505589e59d08336c6cad992f49
https://pubmed.ncbi.nlm.nih.gov/28407431

Quantitative NMR Metabolite Profiling of Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Discriminates between Biofilm and Planktonic Phenotypes

Autor: Michael A Gross, Jessica J. Stanisich, Kelly R. Kirker, Valérie Copié, Brian P. Tripet, Ross P. Carlson, Mary Cloud B. Ammons

Publikováno v: Journal of Proteome Research

Wound bioburden in the form of colonizing biofilms is a major contributor to nonhealing wounds. Staphylococcus aureus is a Gram-positive, facultative anaerobe commonly found in chronic wounds; however, much remains unknown about the basic physiology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f425efe3baba97af066b958dfe0cae9
http://europepmc.org/articles/PMC4059261

Differential effects of planktonic and biofilm MRSA on human fibroblasts

Autor: Kelly R. Kirker, Philip Fleckman, Garth A. James, Philip S. Stewart, John E. Olerud

Publikováno v: Wound Repair and Regeneration. 20:253-261

Bacteria colonizing chronic wounds often exist as biofilms, yet their role in chronic wound pathogenesis remains unclear. Staphylococcus aureus biofilms induce apoptosis in dermal keratinocytes, and given that chronic wound biofilms also colonize der

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af24b804d95ab2170faaf0db85771ef4
https://doi.org/10.1111/j.1524-475x.2012.00769.x