Výsledky vyhledávání - "Kelly R, Kenna"

Quantitative lung ultrasound detects dynamic changes in lung recruitment in the preterm lamb

Autor: Arun Sett, Gillian W. C. Foo, Kelly R. Kenna, Rebecca J. Sutton, Elizabeth J. Perkins, Magdy Sourial, Sheryle R. Rogerson, Brett J. Manley, Peter G. Davis, Prue M. Pereira-Fantini, David G. Tingay

Publikováno v: Pediatric Research. 93:1591-1598

Background Lung ultrasound (LUS) may not detect small, dynamic changes in lung volume. Mean greyscale measurement using computer-assisted image analysis (Q-LUSMGV) may improve the precision of these measurements. Methods Preterm lambs (n = 40) underw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cce082f6e8bdc51bcffca5b5ce4f88e7
https://doi.org/10.1038/s41390-022-02316-0

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Divergent effects of initial ventilation with delayed cord clamping on systemic and pulmonary arterial flows in the birth transition of preterm lambs

Autor: Joseph J. Smolich, Kelly R. Kenna

Publikováno v: The Journal of Physiology. 600:3585-3601

A current view that delayed cord clamping (DCC) results in greater haemodynamic stability at birth than immediate cord clamping (ICC) is based on comparison of DCC vs. ICC followed by an asphyxial (∼2 min) cord clamp-to-ventilation (CC-V) interval.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407ead821f4bacf6d292b2abcda70045
https://doi.org/10.1113/jp282934

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Characteristics and physiological basis of falls in ventricular outputs after immediate cord clamping at delivery in preterm fetal lambs

Autor: Michael M. M. Cheung, Gavin W. Lambert, Joseph J. Smolich, Sarah E. Phillips, Kelly R. Kenna, Jonathan P. Mynard

Publikováno v: The Journal of Physiology. 599:3755-3770

Key points Controversy exists about the physiological mechanism(s) underlying decreases in cardiac output after immediate clamping of the umbilical cord at birth. To define these mechanisms, the four major determinants of ventricular output (afterloa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94756477856f749dcf9c9876e30ffc7
https://doi.org/10.1113/jp281693

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Quantitative lung ultrasound detects dynamic changes in lung recruitment in the preterm lamb

Autor: Arun, Sett, Gillian W C, Foo, Kelly R, Kenna, Rebecca J, Sutton, Elizabeth J, Perkins, Magdy, Sourial, Sheryle R, Rogerson, Brett J, Manley, Peter G, Davis, Prue M, Pereira-Fantini, David G, Tingay

Publikováno v: Pediatric research.

Lung ultrasound (LUS) may not detect small, dynamic changes in lung volume. Mean greyscale measurement using computer-assisted image analysis (Q-LUSPreterm lambs (n = 40) underwent LUS of the dependent or non-dependent lung during static pressure-vol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0a49f56272fabda90f6c093f3e5e29e
https://pubmed.ncbi.nlm.nih.gov/36167816

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Aeration strategy at birth does not impact carotid haemodynamics in preterm lambs

Autor: Sophia I, Dahm, Kelly R, Kenna, David, Stewart, Prue M, Pereira-Fantini, Karen E, McCall, Elizabeth J, Perkins, Magdy, Sourial, David G, Tingay

Publikováno v: Pediatric research.

The impact of different respiratory strategies at birth on the preterm lung is well understood; however, concerns have been raised that lung recruitment may impede cerebral haemodynamics. This study aims to examine the effect of three different venti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::943c820f2792639d329148791ffadfda
https://pubmed.ncbi.nlm.nih.gov/35974157

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Brief asphyxial state following immediate cord clamping accelerates onset of left-to-right shunting across the ductus arteriosus after birth in preterm lambs

Autor: Michael Cheung, Joseph J. Smolich, Jonathan P. Mynard, Kelly R. Kenna

Publikováno v: Journal of Applied Physiology. 128:429-439

Reversal of shunting across the ductus arteriosus from right-to-left to left-to-right is a characteristic feature of the birth transition. Given that immediate cord clamping (ICC) followed by an asphyxial cord clamp-to-ventilation (CC-V) interval may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36682818dde5cd69465fdfaa13d319a7
https://doi.org/10.1152/japplphysiol.00559.2019

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Lung ultrasound of the dependent lung detects real-time changes in lung volume in the preterm lamb

Autor: Arun Sett, Kelly R Kenna, Rebecca J Sutton, Elizabeth J Perkins, Magdy Sourial, Jack D Chapman, Susan M Donath, Arun Sasi, Sheryle R Rogerson, Brett J Manley, Peter G Davis, Prue M Pereira-Fantini, David G Tingay

Publikováno v: Archives of disease in childhood. Fetal and neonatal edition. 108(1)

BackgroundEffective lung protective ventilation requires reliable, real-time estimation of lung volume at the bedside. Neonatal clinicians lack a readily available imaging tool for this purpose.ObjectiveTo determine the ability of lung ultrasound (LU

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9cd56a54748b83ed7fb64e6bcfc1d69
https://pubmed.ncbi.nlm.nih.gov/35750468

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S-Nitrosoglutathione Limits Apoptosis and Reduces Pulmonary Vascular Dysfunction After Bypass

Autor: M. Cheung, Freya L. Sheeran, Roberto Chiletti, Julie Angerosa, Martin Bennet, Kelly R. Kenna, Stéphanie Perrier, Diana Zannino, Johann Brink, Joseph J. Smolich, Salvatore Pepe

Publikováno v: The Annals of thoracic surgery. 114(4)

Background During hypoxia or acidosis, S-nitrosoglutathione (GSNO) has been shown to protect the cardiomyocyte from IR injury. In a randomised double blinded control study of a porcine model of paediatric CPB, we aimed to evaluate the effects of two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336caf2eb69ad9c7cfbc3006085e12cf
https://pubmed.ncbi.nlm.nih.gov/34416229

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Greater sympathoadrenal activation with longer preventilation intervals after immediate cord clamping increases hemodynamic lability at birth in preterm lambs

Autor: Gavin W. Lambert, Sarah E. Phillips, Joseph J. Smolich, Kelly R. Kenna, Murray D. Esler

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 312:R903-R911

This study tested the hypothesis that varying degrees of hemodynamic fluctuations seen after birth following immediate cord clamping were related to development of asphyxia with longer cord clamp-to-ventilation intervals, resulting in higher perinata

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc346291dbd63fe9f4254f23e685452
https://doi.org/10.1152/ajpregu.00064.2017

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Antenatal betamethasone augments early rise in pulmonary perfusion at birth in preterm lambs: role of ductal shunting and right ventricular outflow distribution

Autor: Kelly R. Kenna, Joseph J. Smolich, Jonathan P. Mynard

Publikováno v: Am J Physiol Regul Integr Comp Physiol

The glucocorticosteroid betamethasone is routinely administered via maternal intramuscular injection to enhance fetal lung maturation before anticipated preterm birth. Although antenatal betamethasone increases fetal pulmonary arterial (PA) blood flo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14a79ef9eb7df53cb69b37c8a4a55cf
https://europepmc.org/articles/PMC7059881/

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