Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kelly Pu"'
Autor:
Michael W.K. Fong, Kelly Pu, Rakesh Jadav, Tasleema Khan, Lawrence J. Hirsch, Hitten P. Zaveri
Publikováno v:
Clinical Neurophysiology. 150:98-105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef767805fb51abbf76f732d8a12eb370
https://doi.org/10.1016/j.clinph.2023.03.011
https://doi.org/10.1016/j.clinph.2023.03.011
Autor:
Tetsuhiro Harimoto, Jaeseung Hahn, Yu-Yu Chen, Jongwon Im, Joanna Zhang, Nicholas Hou, Fangda Li, Courtney Coker, Kelsey Gray, Nicole Harr, Sreyan Chowdhury, Kelly Pu, Clare Nimura, Nicholas Arpaia, Kam W. Leong, Tal Danino
Publikováno v:
Nature Biotechnology. 40:1259-1269
Living bacteria therapies have been proposed as an alternative approach to treating a broad array of cancers. In this study, we developed a genetically encoded microbial encapsulation system with tunable and dynamic expression of surface capsular pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13efedc2a6b0396db363a90ddc6073c
https://doi.org/10.1038/s41587-022-01244-y
https://doi.org/10.1038/s41587-022-01244-y
Autor:
Thomas M. Savage, Rosa L. Vincent, Sarah S. Rae, Lei Haley Huang, Alexander Ahn, Kelly Pu, Fangda Li, Kenia de los Santos-Alexis, Courtney Coker, Tal Danino, Nicholas Arpaia
Publikováno v:
Science Advances. 9
Tumors use multiple mechanisms to actively exclude immune cells involved in antitumor immunity. Strategies to overcome these exclusion signals remain limited due to an inability to target therapeutics specifically to the tumor. Synthetic biology enab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b08fbeb0493d4ab45bba4825eed5e8f
https://doi.org/10.1126/sciadv.adc9436
https://doi.org/10.1126/sciadv.adc9436
Autor:
Thomas M. Savage, Rosa L. Vincent, Sarah S. Rae, Lei Haley Huang, Alexander Ahn, Kelly Pu, Fangda Li, Courtney Coker, Tal Danino, Nicholas Arpaia
Tumors employ multiple mechanisms to actively exclude or suppress adaptive immune cells involved in anti-tumor immunity. Strategies focused on overcoming these immunosuppressive or exclusion signals – through localized delivery of chemokines that d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de064e15d0e5693cbe95cd7471fda696
https://doi.org/10.1101/2022.06.16.496462
https://doi.org/10.1101/2022.06.16.496462
Autor:
Clare Nimura, Tetsuhiro Harimoto, Jaeseung Hahn, Nicholas Hou, Sreyan Chowdhury, Jongwon Im, Yu-Yu Chen, Kelly Pu, Courtney Coker, Kelsey Gray, Kam W. Leong, Tal Danino, Nicole Harr, Joanna Zhang, Fangda Li, Nicholas Arpaia
Recent advances in therapeutic modulation of human microbiota have driven new efforts to engineer living microbial medicines using synthetic biology. However, a long-standing challenge for live bacterial therapies is balancing the high dose required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77080e88fc039e5522ffe8769895204c
https://doi.org/10.1101/2021.08.03.454638
https://doi.org/10.1101/2021.08.03.454638
Abstract 1074: Programmable bacteria induce durable tumor regression and systemic antitumor immunity
Autor:
Clare Nimura, Tal Danino, Kelly Pu, Taylor E. Hinchliffe, Samuel Castro, Sreyan Chowdhury, Nicholas Arpaia, Courtney Coker
Publikováno v:
Cancer Research. 80:1074-1074
Synthetic biology is driving a new era of medicine through the engineering of living cells. This transformative approach allows for the creation of systems that intelligently sense and respond to diverse environments, adding specificity and efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::014ce98402f0f8b5f9ca3560032c7906
https://doi.org/10.1158/1538-7445.am2020-1074
https://doi.org/10.1158/1538-7445.am2020-1074
Autor:
Kelsey Gray, Nicholas Hou, Courtney Coker, Andoni Nolasco, Tal Danino, Kelly Pu, Tetsuhiro Harimoto, Martina Pavlicova, Benjamin Kepecs, Tamjeed Azad, Tiffany Chien
Publikováno v:
Nat Biomed Eng
Engineered bacteria for therapeutic applications would benefit from control mechanisms that confine the growth of the bacteria within specific tissues or regions in the body. Here we show that the tropism of engineered bacteria can be enhanced by cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d1a6819b700fb39dc9b34bed5d9e1f
https://pubmed.ncbi.nlm.nih.gov/34326488
https://pubmed.ncbi.nlm.nih.gov/34326488
Autor:
Courtney Coker, Kelly Pu, Benjamin Kepecs, Kelsey Gray, Tetsuhiro Harimoto, Tamjeed Azad, Tal Danino, Tiffany Chien
The engineering of microbes spurs biotechnological innovations, but requires control mechanisms to confine growth within defined environments for translation. Here we engineer bacterial growth tropism to sense and grow in response to specified oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa77851a710717ece0ffc1a651a1a163
Autor:
Toit, Gerard du (AUTHOR), Mitscherlich, Alexander (AUTHOR), Ojha, Nikhil (AUTHOR), Pu, Kelly (AUTHOR)
Publikováno v:
Fortune.com. 9/15/2022, pN.PAG-N.PAG. 1p.
Publikováno v:
Immunotherapy Weekly; 3/31/2023, p1815-1815, 1p