Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kelly P. Longo"'
Publikováno v:
Licere, Vol 26, Iss 1 (2023)
O presente estudo tem por objetivo principal identificar através de revisão integrativa de literatura as produções acerca do lazer no contexto educacional, publicados nos periódicos da Revista do Programa de Pós-Graduação Interdisciplinar em
Externí odkaz:
https://doaj.org/article/3f392d4f6ecc41d7aee99459b5265abc
Autor:
Frank E. Ewing, Jon Bordner, Wesley Lebel, Heidi A. Woody, R. Michael Snider, Kelly P. Longo, Jay W. Constantine, John A. Lowe
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:839-842
The synthesis and SAR of a series of 2-aryl-1-azabicyclo[2.2.2]octanes structurally related to the nonpeptide substance P antagonists CP-96,345 and CP-99,994 are described. The novel SAR observed at the 2-position in these derivatives represents a hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9127aa76d8f80b8e1ac787e2a9a59dfa
https://doi.org/10.1016/s0960-894x(01)80859-3
https://doi.org/10.1016/s0960-894x(01)80859-3
Autor:
Stevin H. Zorn, Yoshihito Kanai, R.M. Snider, Osamu Suga, John A. Lowe, Jon Bordner, Susan E. Drozda, Stafford McLean, Jackson Elisa Rose, Megumi Tsuchiya, Atsushi Nagahisa, Jean Morrone, Dianne K. Bryce, Kelly P. Longo
Publikováno v:
Regulatory Peptides. 46:20-23
Studies with CP-96,345, a potent, selective, orally active, nonpeptide NK1 receptor antagonist, have provided considerable insight into SP pharmacology. Rather than being a primary neurotransmitter, SP prolongs the nociception produced by other neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0eb57110f8c619f44617429deb04f6e
https://doi.org/10.1016/0167-0115(93)90006-t
https://doi.org/10.1016/0167-0115(93)90006-t
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:921-924
The synthesis and SAR of a series of 1-azabicyclo[3.2.2] analogues of the nonpeptide substance P antagonist CP-96,345 are described. The results demonstrate the sensitivity of the substance P receptor toward alterations in the nuclear structure of CP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::172fdc669059076c76d4587149c81799
https://doi.org/10.1016/s0960-894x(00)80693-9
https://doi.org/10.1016/s0960-894x(00)80693-9
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcde2ede013efa4e1dbee829fc72bd28
https://doi.org/10.1002/chin.199135169
https://doi.org/10.1002/chin.199135169
Autor:
Frederic J. Vinick, Jacqueline N. Crawley, R. Michael Snider, Kelly P. Longo, Ralph E. Davidson, Ece Genc-Sehitoglu, Kirsti Laitinen, Dennis A. Pereira
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:1535-1540
UK-73,093 was identified in a screening program as a compound able to displace [ 3 H]-neurotensin from its bovine brain receptor. We describe the discovery of this compound, species differences in receptor affinity and its characterization as a funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0724fe455615308a307ed33778f6ffe7
https://doi.org/10.1016/s0960-894x(00)80423-0
https://doi.org/10.1016/s0960-894x(00)80423-0
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 1:129-132
The preparation of CP-96,345, a potent, non-peptide Substance P antagonist, in both enantiomerically pure and radiolabelled forms is described. In addition, the absolute configuration of CP-96,345 was determined to be 2S,3S.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb879fb11775301b7a915dcad416e174
https://doi.org/10.1016/s0960-894x(00)80246-2
https://doi.org/10.1016/s0960-894x(00)80246-2
Autor:
Susan E. Drozda, Megumi Tsuchiya, Kelly P. Longo, Stafford McLean, Rosemary T. Crawford, Atsushi Nagahisa, John A. Lowe, R. M. Snider, Dianne K. Bryce
Publikováno v:
Journal of medicinal chemistry. 37(18)
The synthesis and structure-activity relationships of a series of aza-tricyclic analogs of the quinuclidine substance P (SP) antagonist 1 are described. The SP receptor affinity of these compounds was found to vary according to the size of the new ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e39fd727cbf0fe00a735a6d59c6716
https://pubmed.ncbi.nlm.nih.gov/7520943
https://pubmed.ncbi.nlm.nih.gov/7520943
Autor:
Dianne K. Bryce, Kelly P. Longo, Manoj C. Desai, Stafford McLean, R.M. Snider, Terry J. Rosen, Anne W. Schmidt, James Heym
Publikováno v:
Regulatory peptides. 46(1-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58efa5b150b71214df13a9b82f661678
https://pubmed.ncbi.nlm.nih.gov/8210497
https://pubmed.ncbi.nlm.nih.gov/8210497
Autor:
Yoshihito Kanai, R.M. Snider, Kelly P. Longo, Osamu Suga, Jean Morrone, M. Nakagaki, Stevin H. Zorn, Susan E. Drozda, Jackson Elisa Rose, Atsushi Nagahisa, John A. Lowe
Publikováno v:
Regulatory peptides. 46(1-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732f5264e405e5871121a77eb617ae09
https://pubmed.ncbi.nlm.nih.gov/7692519
https://pubmed.ncbi.nlm.nih.gov/7692519