Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kelly M. Ramsbottom"'
Autor:
Mayura V. Wagle, Stephin J. Vervoort, Madison J. Kelly, Willem Van Der Byl, Timothy J. Peters, Ben P. Martin, Luciano G. Martelotto, Simone Nüssing, Kelly M. Ramsbottom, James R. Torpy, Deborah Knight, Sinead Reading, Kevin Thia, Lisa A. Miosge, Debbie R. Howard, Renee Gloury, Sarah S. Gabriel, Daniel T. Utzschneider, Jane Oliaro, Jonathan D. Powell, Fabio Luciani, Joseph A. Trapani, Ricky W. Johnstone, Axel Kallies, Christopher C. Goodnow, Ian A. Parish
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Exhausted T cells arise when chronic activation triggers functional defects. Here the authors show that chronic antigenic stimulation in both tumour and infection models induces the expression of EGR2, which drives and stabilises exhausted cell epige
Externí odkaz:
https://doaj.org/article/835402bfc1a5448994d0c742c77cfabd
Autor:
Emily J. Lelliott, Kelly M. Ramsbottom, Mark R. Dowling, Carolyn Shembrey, Tahereh Noori, Conor J. Kearney, Jessica Michie, Ian A. Parish, Margaret A. Jordan, Alan G. Baxter, Neil D. Young, Amelia J. Brennan, Jane Oliaro
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cytotoxic lymphocytes are essential for anti-tumor immunity, and for effective responses to cancer immunotherapy. Natural killer cell granule protein 7 (NKG7) is expressed at high levels in cytotoxic lymphocytes infiltrating tumors from patients trea
Externí odkaz:
https://doaj.org/article/c8e517cb608a45a58a1cfaec14b8b317
Autor:
Andrew J. Freeman, Stephin J. Vervoort, Kelly M. Ramsbottom, Madison J. Kelly, Jessica Michie, Lizzy Pijpers, Ricky W. Johnstone, Conor J. Kearney, Jane Oliaro
Publikováno v:
Cell Reports, Vol 28, Iss 11, Pp 2784-2794.e5 (2019)
Summary: Despite the clinical success of cancer immunotherapies, the majority of patients fail to respond or develop resistance through disruption of pathways that promote neo-antigen presentation on MHC I molecules. Here, we conducted a series of un
Externí odkaz:
https://doaj.org/article/099c8c10b0f84d1e805bd39d02fcff16
Autor:
Karen E. Sheppard, Jane Oliaro, Grant A. McArthur, Nicole M. Haynes, Anthony T. Papenfuss, Carleen Cullinane, Alison Slater, Riyaben P. Patel, Claire Martin, Laura Kirby, Luciano G. Martelotto, Amanda J. Oliver, Peter K.H. Lau, Lydia Lim, Magnus Zethoven, Kelly M. Ramsbottom, Stefano Mangiola, Emily J. Lelliott
Supplementary Figures S1-S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132b21ff68e5e88683ac5b96348b807a
https://doi.org/10.1158/2326-6066.22543851.v1
https://doi.org/10.1158/2326-6066.22543851.v1
Supplementary Video Legends and Figures from BET Inhibition Enhances TNF-Mediated Antitumor Immunity
Autor:
Ricky W. Johnstone, Daniel Rohle, Astrid Ruefli-Brasse, Jake Shortt, Jane Oliaro, Joseph A. Trapani, Stephin J. Vervoort, Conor J. Kearney, Leonie A. Cluse, Axel Paehler, Phillip Thienger, Laura Jarassier, Daniel Marbach, Tanja Fauti, Marina Bacac, Kelly M. Ramsbottom, Jessica Michie, Daniela Geiss, Thomas Friess, Dane M. Newman, Simon J. Hogg, Lisa C. Wellinger
Supplementary Video Legends and Supplementary Figures 1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596ffec75f56502f7fc3b097790f0b02
https://doi.org/10.1158/2326-6066.22544825.v1
https://doi.org/10.1158/2326-6066.22544825.v1
Autor:
Karen E. Sheppard, Jane Oliaro, Grant A. McArthur, Nicole M. Haynes, Anthony T. Papenfuss, Carleen Cullinane, Alison Slater, Riyaben P. Patel, Claire Martin, Laura Kirby, Luciano G. Martelotto, Amanda J. Oliver, Peter K.H. Lau, Lydia Lim, Magnus Zethoven, Kelly M. Ramsbottom, Stefano Mangiola, Emily J. Lelliott
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cc462866102b136e414540b347056a
https://doi.org/10.1158/2326-6066.22543848
https://doi.org/10.1158/2326-6066.22543848
Autor:
Ricky W. Johnstone, Daniel Rohle, Astrid Ruefli-Brasse, Jake Shortt, Jane Oliaro, Joseph A. Trapani, Stephin J. Vervoort, Conor J. Kearney, Leonie A. Cluse, Axel Paehler, Phillip Thienger, Laura Jarassier, Daniel Marbach, Tanja Fauti, Marina Bacac, Kelly M. Ramsbottom, Jessica Michie, Daniela Geiss, Thomas Friess, Dane M. Newman, Simon J. Hogg, Lisa C. Wellinger
Supp Video 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c0e02c2126b26631873c3c38e9f971
https://doi.org/10.1158/2326-6066.22544813
https://doi.org/10.1158/2326-6066.22544813
Autor:
Karen E. Sheppard, Jane Oliaro, Grant A. McArthur, Nicole M. Haynes, Anthony T. Papenfuss, Carleen Cullinane, Alison Slater, Riyaben P. Patel, Claire Martin, Laura Kirby, Luciano G. Martelotto, Amanda J. Oliver, Peter K.H. Lau, Lydia Lim, Magnus Zethoven, Kelly M. Ramsbottom, Stefano Mangiola, Emily J. Lelliott
Combined inhibition of BRAF, MEK, and CDK4/6 is currently under evaluation in clinical trials for patients with melanoma harboring a BRAFV600 mutation. While this triple therapy has potent tumor-intrinsic effects, the impact of this combination on an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4345cc594088fa46130e17ff63a50c05
https://doi.org/10.1158/2326-6066.c.6550431.v1
https://doi.org/10.1158/2326-6066.c.6550431.v1
Autor:
Ricky W. Johnstone, Daniel Rohle, Astrid Ruefli-Brasse, Jake Shortt, Jane Oliaro, Joseph A. Trapani, Stephin J. Vervoort, Conor J. Kearney, Leonie A. Cluse, Axel Paehler, Phillip Thienger, Laura Jarassier, Daniel Marbach, Tanja Fauti, Marina Bacac, Kelly M. Ramsbottom, Jessica Michie, Daniela Geiss, Thomas Friess, Dane M. Newman, Simon J. Hogg, Lisa C. Wellinger
Supp Video 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce355851a23ce95f918a2f491248d128
https://doi.org/10.1158/2326-6066.22544807.v1
https://doi.org/10.1158/2326-6066.22544807.v1
Autor:
Ricky W. Johnstone, Daniel Rohle, Astrid Ruefli-Brasse, Jake Shortt, Jane Oliaro, Joseph A. Trapani, Stephin J. Vervoort, Conor J. Kearney, Leonie A. Cluse, Axel Paehler, Phillip Thienger, Laura Jarassier, Daniel Marbach, Tanja Fauti, Marina Bacac, Kelly M. Ramsbottom, Jessica Michie, Daniela Geiss, Thomas Friess, Dane M. Newman, Simon J. Hogg, Lisa C. Wellinger
Cell lines used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5409e92079b8a98efa55398a74dd3414
https://doi.org/10.1158/2326-6066.22544828.v1
https://doi.org/10.1158/2326-6066.22544828.v1