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pro vyhledávání: '"Kelly M. Montgomery"'
Autor:
Kelly M. Montgomery, Emma C. Carroll, Aye C. Thwin, Athena Y. Quddus, Paige Hodges, Daniel R. Southworth, Jason E. Gestwicki
Publikováno v:
Journal of the American Chemical Society. 145:3926-3936
Autor:
Kelly M. Montgomery, Emma C. Carroll, Aye Thwin, Paige Hodges, Daniel R. Southworth, Jason E. Gestwicki
The aggregation of tau into insoluble fibrils is a defining feature of neurodegenerative tauopathies. However, tau has a positive overall charge and is highly soluble; so polyanions, such as heparin, are typically required to promote its aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe02369dce0c90a0da3d57c1643b73bc
https://doi.org/10.1101/2022.07.28.501920
https://doi.org/10.1101/2022.07.28.501920
Publikováno v:
Stroke. 53
Background: University Hospitals Comprehensive Stroke Center (UH CSC) is an academic medical center with a dedicated 19 bed Neuroscience Intensive Care unit (NSU). As the only comprehensive stroke center in a 22 hospital system, the majority of ische
Publikováno v:
Stroke. 53
Introduction: High value care aims to provide the best patient outcomes while avoiding defects and waste. Our previous work determined that 39% of patients transferred for possible thrombectomy based on clinical criteria and CT only did not have a la
Autor:
Ke Xu, Erik D. Roberson, Rui Yan, Shiaoching Gong, Celeste M. Karch, Kelly M. Montgomery, Kenneth S. Kosik, Manni He, Cindy Tzu-Ling Huang, Rebecca Freilich, Carolina M. Camargo, Sue-Ann Mok, Tara E. Tracy, Li Fan, Peter Dongmin Sohn, Justin Baik, Taylor Arhar, Li Gan, Jason E. Gestwicki
Publikováno v:
Neuron, vol 104, iss 3
Dysregulation of neuronal excitability underlies the pathogenesis of tauopathies, including frontotemporal dementia (FTD) with tau inclusions. A majority of FTD-causing tau mutations are located in the microtubule-binding domain, but how these mutati