Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kelly M. Hinkle"'
Autor:
Angela M. Crist, Kelly M. Hinkle, Xue Wang, Christina M. Moloney, Billie J. Matchett, Sydney A. Labuzan, Isabelle Frankenhauser, Nkem O. Azu, Amanda M. Liesinger, Elizabeth R. Lesser, Daniel J. Serie, Zachary S. Quicksall, Tulsi A. Patel, Troy P. Carnwath, Michael DeTure, Xiaojia Tang, Ronald C. Petersen, Ranjan Duara, Neill R. Graff-Radford, Mariet Allen, Minerva M. Carrasquillo, Hu Li, Owen A. Ross, Nilüfer Ertekin-Taner, Dennis W. Dickson, Yan W. Asmann, Rickey E. Carter, Melissa E. Murray
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Alzheimer’s disease (AD) is typically associated with hippocampal and cortical pathology, although hippocampal sparing and limbic predominant forms exist. The authors use transcriptomic analysis and neuropathology to identify genes associated with
Externí odkaz:
https://doaj.org/article/4cd05f374d8e492f8281dd38dc11f183
Autor:
Yari Carlomagno, Dah-eun Chloe Chung, Mei Yue, Aishe Kurti, Nicole M. Avendano, Monica Castanedes-Casey, Kelly M. Hinkle, Karen Jansen-West, Lillian M. Daughrity, Jimei Tong, Virginia Phillips, Rosa Rademakers, Michael DeTure, John D. Fryer, Dennis W. Dickson, Leonard Petrucelli, Casey Cook
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Pathogenic mutations in the tau gene (microtubule associated protein tau, MAPT) are linked to the onset of tauopathy, but the A152T variant is unique in acting as a risk factor for a range of disorders including Alzheimer’s disease (AD), p
Externí odkaz:
https://doaj.org/article/01ef1476c69f420aa2d92a6235cfe2dd
Autor:
Tiffany N. Hicks Sirmans, Naomi Kouri, Nicole Tamvaka, Sydney A Labuzan, Billie J Matchett, Sarah J. Lincoln, Kelly M Hinkle, Christina M. Moloney, Zhongwei Peng, Rickey E Carter, Owen A. Ross, Nilufer Ertekin‐Taner, Ranjan Duara, Neill R. Graff‐Radford, Dennis W. Dickson, Melissa E. Murray
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Rosa Rademakers, Billie J. Matchett, Nilufer Ertekin-Taner, Melissa E. Murray, Neill R. Graff-Radford, Kelly M. Hinkle, Sarah Lincoln, Janisse Cabrera-Rodriguez, Dennis W. Dickson, Sydney A. Labuzan, Nikoleta Tamvaka, Baker Matthew Charles, Owen A. Ross, Ranjan Duara, Jacqueline Helminger
Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is the most common cause of dementia. Our previous studies have shown that increased expression of the SERPINA5 gene is associated with hippocampal vulnerability in AD, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e989e39cfd18aa36352441403ebb385d
https://doi.org/10.21203/rs.3.rs-769744/v1
https://doi.org/10.21203/rs.3.rs-769744/v1
Autor:
Owen A. Ross, Otto Pedraza, Maria T. Greig-Custo, Minerva M. Carrasquillo, Amanda M. Liesinger, Kelly M. Hinkle, Ranjan Duara, Kevin F. Bieniek, Fadi S. Hanna Al-Shaikh, Octavio A. Santos, Julia E. Crook, Melissa E. Murray, Dennis W. Dickson, Neill R. Graff-Radford, Nilufer Ertekin-Taner, John A. Lucas, Elizabeth R. Lesser
Publikováno v:
Alzheimer's & dementia : the journal of the Alzheimer's Association
Introduction Our primary goal was to examine demographic and clinicopathologic differences across an ethnoracially diverse autopsy-confirmed cohort of Alzheimer's disease cases. Methods A retrospective study was conducted in the Florida Autopsied Mul
Autor:
Lillian M. Daughrity, John D. Fryer, Monica Castanedes-Casey, Nicole M. Avendano, Virginia Phillips, Casey Cook, Aishe Kurti, Rosa Rademakers, Leonard Petrucelli, Dah Eun Chloe Chung, Jimei Tong, Karen Jansen-West, Dennis W. Dickson, Michael DeTure, Kelly M. Hinkle, Yari Carlomagno, Mei Yue
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-13 (2019)
Acta Neuropathologica Communications
Acta neuropathologica communications
Acta Neuropathologica Communications
Acta neuropathologica communications
Pathogenic mutations in the tau gene (microtubule associated protein tau, MAPT) are linked to the onset of tauopathy, but the A152T variant is unique in acting as a risk factor for a range of disorders including Alzheimer’s disease (AD), progressiv
Autor:
Nkem O. Azu, Daniel J. Serie, Isabelle Frankenhauser, Minerva M. Carrasquillo, Yan W. Asmann, Neill R. Graff-Radford, Amanda M. Liesinger, Nilufer Ertekin-Taner, Elizabeth R. Lesser, Owen A. Ross, Ranjan Duara, Dennis W. Dickson, Mariet Allen, Billie J. Matchett, Michael DeTure, Kelly M. Hinkle, Melissa E. Murray, Christina M. Moloney, Hu Li, Xiaojia Tang, Troy P. Carnwath, Angela M. Crist, Zachary S. Quicksall, Ronald C. Petersen, Rickey E. Carter, Tulsi A. Patel, Sydney A. Labuzan, Xue Wang
SummarySelective vulnerability is a central concept to the myriad of devastating neurodegenerative disorders. Although hippocampus and cortex are selectively vulnerable in Alzheimer’s disease (AD), the degree of involvement lies along a spectrum th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a52bf8dcba78d663c4dfef48f9198f0
https://doi.org/10.1101/2020.12.18.423469
https://doi.org/10.1101/2020.12.18.423469
Autor:
Sydney A. Labuzan, Amanda M. Liesinger, Owen A. Ross, Christina M. Moloney, Neill R. Graff-Radford, Elizabeth R. Lesser, Xue Wang, Melissa E. Murray, Minerva M. Carrasquillo, Nilufer Ertekin-Taner, Yan W. Asmann, Isabelle Frankenhauser, Nkem O. Azu, Michael DeTure, Leonard Petrucelli, Billie J. Matchett, Mariet Allen, Kelly M. Hinkle, Hu Li, Ronald C. Petersen, Angela M. Crist, Rickey E. Carter, Dennis W. Dickson, Casey Cook, Ranjan Duara, Daniel J. Serie
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Neill R. Graff-Radford, Amanda M. Liesinger, Owen A. Ross, Shunsuke Koga, Fadi S. Hanna Al-Shaikh, Kelly M. Hinkle, Rickey E. Carter, Adel Aziz, Melissa E. Murray, Nilufer Ertekin-Taner, McKenna K.F. Johnson, Sarah K. Dilello, Ranjan Duara, Dennis W. Dickson
Publikováno v:
Acta Neuropathologica
Women reportedly make up two-thirds of Alzheimer’s disease (AD) dementia sufferers. Many estimates regarding AD, however, are based on clinical series lacking autopsy confirmation. The Florida Autopsied Multi-Ethnic (FLAME) cohort was queried for A
Autor:
Ranjan Duara, Elizabeth R. Lesser, Julia E. Crook, Fadi S. Hanna Al-Shaikh, Melissa E. Murray, Owen A. Ross, Nilufer Ertekin-Taner, Dennis W. Dickson, Neill R. Graff-Radford, Kelly M. Hinkle, Otto Pedraza, Jolien Schaeverbeke
Publikováno v:
JAMA neurology. 77(2)
IMPORTANCE: Corticolimbic patterns of neurofibrillary tangle (NFT) accumulation define neuropathologic subtypes of Alzheimer disease (AD), which underlie the clinical heterogeneity observed antemortem. The cholinergic system, which is the target of a