Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kelly M. George"'
Autor:
Shirley Li, Kelly M. George, Shelley K. Gleason, Charles Wartchow, Binh Thanh Vu, Hong Qian, Ann C. Petersen, Qing-Fen Gan, Lin Gao, Gabriel Stephen Deems, Linghao Niu, Nanda Beatini, Johannes C. Hermann, Arjun Narayanan, John Menke, Nathan Robert Scott, Nancy-Ellen Haynes, Yingsi Chen
Publikováno v:
ACS Medicinal Chemistry Letters. 4:197-200
Organic impurities in compound libraries are known to often cause false-positive signals in screening campaigns for new leads, but organic impurities do not fully account for all false-positive results. We discovered inorganic impurities in our scree
Publikováno v:
The Journal of Organic Chemistry. 68:9533-9540
The 13-step synthesis of (+)-isoschizandrin reported herein features a samarium(II) iodide-promoted 8-endo ketyl-olefin coupling to assemble the eight-membered ring present in the target concomitantly with the required functionality and stereochemist
Autor:
Kelly M. George
Publikováno v:
e-EROS Encyclopedia of Reagents for Organic Synthesis
[898-22-6] C12H15N3O6 (MW 297.26) InChI = 1S/C12H15N3O6/c1-4-19-10(16)7-13-8(11(17)20-5-2)15-9(14-7)12(18)21-6-3/h4-6H2,1-3H3 InChIKey = LKNPNZKIOSOWES-UHFFFAOYSA-N (reagent widely used in [4 + 2] cycloadditions with dienophiles and as a building blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f4a83091b9949c914f442164bc436b4
https://doi.org/10.1002/047084289x.rn01134
https://doi.org/10.1002/047084289x.rn01134
Autor:
Kelly M. George, Robert J. Boeckman
Publikováno v:
e-EROS Encyclopedia of Reagents for Organic Synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a777f56dc8f6f486e6368758e63ebb69
https://doi.org/10.1002/047084289x.rt157m.pub2
https://doi.org/10.1002/047084289x.rt157m.pub2
Autor:
Adam Golebiowski, Kumar D. Thakur, Biswanath De, Michael P. Clark, John C. VanRens, Vijay Easwaran, Ed J. Cabrera, Matthew J. Laufersweiler, Jan Richard Davis, Jennifer A. Maier, Mark Sabat, Steven K. Laughlin, Kelly M. George, Jack J. Chen, Roger G. Bookland, Todd A. Brugel, Mark E. Webster, Wenlin Lee, George Zhang
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(5)
A new class of bicyclic pyrrolopyrimidine-based Janus kinase 3 (JAK-3) inhibitors are described. Many of these inhibitors showed low nanomolar activity against JAK-3.
Autor:
Jan Richard Davis, Kumar D. Thakur, Biswanath De, Kelly M. George, Steven K. Laughlin, Vijay Easwaran, Jack J. Chen, Roger G. Bookland, Edward J. Cabrera, Y. George Zhang, Michael P. Clark
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(21)
A new class of pyrimidine-based Janus tyrosine kinase 3 (JAK3) inhibitors are described. Many of these inhibitors showed low nanomolar activity against JAK3.
Autor:
Gary A. Molander, Kelly M. George
Publisher Summary This chapter details the examination process utilized to study the use of samarium (II) iodide in the construction of carbocycles and heterocycles utilizing ketyl-olefin cyclizations. Samarium diiodide is usually featured as a mild,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa888e248a5e1e35d5bd7ee8982322d6
https://doi.org/10.1016/s1874-6004(05)80028-0
https://doi.org/10.1016/s1874-6004(05)80028-0
Publikováno v:
ChemInform. 35
The 13-step synthesis of (+)-isoschizandrin reported herein features a samarium(II) iodide-promoted 8-endo ketyl-olefin coupling to assemble the eight-membered ring present in the target concomitantly with the required functionality and stereochemist