Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kelly M. Cahill"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Recent advances in large-scale gene expression profiling necessitate concurrent development of biostatistical approaches to reveal meaningful biological relationships. Most analyses rely on significance thresholds for identifying differentia
Externí odkaz:
https://doaj.org/article/ea08d28b830a44899508fdecbeb39c8d
Autor:
Rachel Puralewski, Kelly Barko, Ryan W. Logan, William Paden, Micah A. Shelton, George C. Tseng, Marianne L. Seney, Kelly M. Cahill, Zhiguang Huo
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-14 (2020)
Translational Psychiatry
Translational Psychiatry
Women are approximately two times as likely to be diagnosed with major depressive disorder (MDD) compared to men. While sex differences in MDD might be driven by circulating gonadal hormones, we hypothesized that developmental hormone exposure and/or
Autor:
Kyle D. Ketchesin, Wei Zong, Mariah A. Hildebrand, Madeline R. Scott, Marianne L. Seney, Kelly M. Cahill, Vaishnavi G. Shankar, Jill R. Glausier, David A. Lewis, George C. Tseng, Colleen A. McClung
Publikováno v:
Biological psychiatry.
Psychosis is a defining feature of schizophrenia and highly prevalent in bipolar disorder. Notably, individuals with these illnesses also have major disruptions in sleep and circadian rhythms, and disturbances of sleep and circadian rhythms can preci
Autor:
George C. Tseng, Wei Zong, Jill R. Glausier, Vaishnavi G. Shankar, Kelly M. Cahill, Madeline R. Scott, David A. Lewis, Kyle D. Ketchesin, Colleen A. McClung, Marianne L. Seney, Mariah A. Hildebrand
Publikováno v:
Proc Natl Acad Sci U S A
The human striatum can be subdivided into the caudate, putamen, and nucleus accumbens (NAc). Each of these structures have some overlapping and some distinct functions related to motor control, cognitive processing, motivation, and reward. Previously
Autor:
David A. Lewis, Ryan W. Logan, Rachel Puralewski, Zhiguang Huo, George C. Tseng, Joyce Zhang, Etienne Sibille, Leon French, Kelly M. Cahill, Marianne L. Seney
Publikováno v:
Biological Psychiatry. 84:18-27
Background Major depressive disorder (MDD) affects women approximately twice as often as men. Women are three times as likely to have atypical depression, with hypersomnia and weight gain. This suggests that the molecular mechanisms of MDD may differ
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Recent advances in large-scale gene expression profiling necessitate concurrent development of biostatistical approaches to reveal meaningful biological relationships. Most analyses rely on significance thresholds for identifying differentially expre
Autor:
Wei Zhong, Madeline R. Scott, George C. Tseng, Kelly M. Cahill, Kyle D. Ketchesin, Colleen A. McClung, David A. Lewis, Vaish Shankar, Mariah A. Hildebrand, Jill R. Glausier, Marianne L. Seney
Publikováno v:
Biological Psychiatry. 89:S71-S72
Autor:
John F. Enwright, Colleen A. McClung, Marianne L. Seney, Ryan W. Logan, George C. Tseng, Zhiguang Huo, Wei Zong, Kelly M. Cahill
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Schizophrenia is associated with disrupted cognitive control and sleep-wake cycles. Here we identify diurnal rhythms in gene expression in the human dorsolateral prefrontal cortex (dlPFC), in schizophrenia and control subjects. We find significant di
Publikováno v:
Mol Neuropsychiatry
Women are twice as likely as men to be diagnosed with major depressive disorder (MDD). Recent studies report distinct molecular changes in depressed men and women across mesocorticolimbic brain regions. However, it is unclear which sex-related factor
Autor:
Jacqui Rabkin, Eric J. Nestler, Casey K. Lardner, Deena M. Walker, Kelly M. Cahill, Li Shen, Zachary S. Lorsch, Marie A. Doyle, Erin S. Calipari, Immanuel Purushothaman, Philipp Mews, Marianne L. Seney, Yong-Hwee E. Loh, Hannah M. Cates, Aarthi Ramakrishnan, Rosemary C. Bagot, Ryan W. Logan, Jian Feng, Arthur Godino, Benoit Labonté, Ja Wook Koo, Hope Kronman
Publikováno v:
Biological psychiatry. 84(12)
Background Global changes in gene expression underlying circuit and behavioral dysregulation associated with cocaine addiction remain incompletely understood. Here, we show how a history of cocaine self-administration (SA) reprograms transcriptome-wi